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List of works by Tsuyoshi Uehara

A highly coordinated cell wall degradation machine governs spore morphogenesis in Bacillus subtilis

scientific article

A pathway-directed screen for inhibitors of the bacterial cell elongation machinery

scientific article published on 21 December 2018

A temperature-sensitive replicon enables efficient gene inactivation in Pseudomonas aeruginosa.

scientific article published on 3 November 2017

Acylated-acyl carrier protein stabilizes the Pseudomonas aeruginosa WaaP lipopolysaccharide heptose kinase

scientific article published on 20 September 2018

An ATP-binding cassette transporter-like complex governs cell-wall hydrolysis at the bacterial cytokinetic ring.

scientific article published on 17 October 2011

An anhydro-N-acetylmuramyl-L-alanine amidase with broad specificity tethered to the outer membrane of Escherichia coli

scientific article

Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery

scientific article

Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity.

scientific article published on 11 April 2016

Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation

scientific article published on 4 April 2008

How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan)

scientific article published on June 2008

Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases.

scientific article

LytM-domain factors are required for daughter cell separation and rapid ampicillin-induced lysis in Escherichia coli.

scientific article published on 12 June 2009

Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae

scientific article published on 24 September 2018

Molecular characterization and verification of azido-3,8-dideoxy-d-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide

scientific article published on 9 October 2017

More than just lysins: peptidoglycan hydrolases tailor the cell wall

scientific article

MurQ Etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall

scientific article

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.

scientific article published on 4 January 2018

Peptidoglycan Recycling.

scientific article published on September 2008

Recycling of the anhydro-N-acetylmuramic acid derived from cell wall murein involves a two-step conversion to N-acetylglucosamine-phosphate.

scientific article

SEDS proteins are a widespread family of bacterial cell wall polymerases

scientific article published on 15 August 2016

Structural and Biological Basis of Small Molecule Inhibition of Escherichia coli LpxD Acyltransferase Essential for Lipopolysaccharide Biosynthesis

scientific article published on 22 August 2019

Structure–function analysis of the LytM domain of EnvC, an activator of cell wall remodelling at the Escherichia coli division site

scientific article published on July 23, 2013

Targeted lipopolysaccharide biosynthetic intermediate analysis with normal-phase liquid chromatography mass spectrometry

scientific article published on 08 February 2019

The Legionella pneumophila EnhC Protein Interferes with Immunostimulatory Muramyl Peptide Production to Evade Innate Immunity

scientific article published on August 16, 2012

The N-acetyl-D-glucosamine kinase of Escherichia coli and its role in murein recycling

scientific article

The Next-Generation β-Lactamase Inhibitor Taniborbactam Restores the Morphological Effects of Cefepime in KPC-Producing Escherichia coli

scientific article published in 2021

Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis

scientific article published on 17 February 2020