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List of works by David A Six

A pathway-directed positive growth restoration assay to facilitate the discovery of lipid A and fatty acid biosynthesis inhibitors in Acinetobacter baumannii.

scientific article published on 5 March 2018

Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis.

scientific article published on 14 December 2015

Defects in Efflux (oprM), β-Lactamase (ampC), and Lipopolysaccharide Transport (lptE) Genes Mediate Antibiotic Hypersusceptibility of Pseudomonas aeruginosa Strain Z61

scientific article published on 24 June 2019

Deletion of the β-acetoacetyl synthase FabY in Pseudomonas aeruginosa induces hypoacylation of lipopolysaccharide and increases antimicrobial susceptibility

scientific journal article

Density gradient enrichment of Escherichia coli lpxL mutants.

scientific article published on 14 April 2012

Development and Optimization of a Higher-Throughput Bacterial Compound Accumulation Assay

scientific article published on 30 January 2019

Differential inhibition of group IVA and group VIA phospholipases A2 by 2-oxoamides

scientific article published on May 2006

Discovery of new biosynthetic pathways: the lipid A story.

scientific article

Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity

scientific article published on 2 April 2003

In vivo phospholipase activity of the Pseudomonas aeruginosa cytotoxin ExoU and protection of mammalian cells with phospholipase A2 inhibitors

scientific article published on 12 August 2003

Inhibition of group IVA cytosolic phospholipase A2 by novel 2-oxoamides in vitro, in cells, and in vivo

scientific article published on July 2004

Lipidomics reveals a remarkable diversity of lipids in human plasma ⬇️

scientific article

Metabolic phospholipid labeling of intact bacteria enables a fluorescence assay that detects compromised outer membranes

scientific article published on 10 March 2020

Molecular Probes for the Determination of Subcellular Compound Exposure Profiles in Gram-Negative Bacteria

scientific article published on 15 June 2018

Molecular characterization and verification of azido-3,8-dideoxy-d-manno-oct-2-ulosonic acid incorporation into bacterial lipopolysaccharide

scientific article published on 9 October 2017

Novel 2-oxoamide inhibitors of human group IVA phospholipase A(2).

scientific article published in July 2002

Palmitoylation State Impacts Induction of Innate and Acquired Immunity by the Salmonella enterica Serovar Typhimurium msbB Mutant

scientific article published in March 2012

Palmitoylation state impacts induction of innate and acquired immunity by the Salmonella enterica serovar typhimurium msbB mutant

scientific article published on 19 September 2011

Pathogenicity of Yersinia pestis synthesis of 1-dephosphorylated lipid A.

scientific article published on 28 January 2013

Phosphate groups of lipid A are essential for Salmonella enterica serovar Typhimurium virulence and affect innate and adaptive immunity

scientific article

Purification and characterization of the lipid A 1-phosphatase LpxE of Rhizobium leguminosarum.

scientific article published on 4 November 2008

Purification and mutagenesis of LpxL, the lauroyltransferase of Escherichia coli lipid A biosynthesis.

scientific article published on 26 July 2008

Salmonella synthesizing 1-dephosphorylated [corrected] lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity.

scientific article

Structure-activity relationship of 2-oxoamide inhibition of group IVA cytosolic phospholipase A2 and group V secreted phospholipase A2.

scientific article published on 2 August 2007

Subcellular Chemical Imaging of Antibiotics in Single Bacteria Using C60-Secondary Ion Mass Spectrometry

scientific article

Synthesis and activity of 2-oxoamides containing long chain beta-amino acids

scientific article published in July 2005

The Next-Generation β-Lactamase Inhibitor Taniborbactam Restores the Morphological Effects of Cefepime in KPC-Producing Escherichia coli

scientific article published in 2021

The sialic acid transporter NanT is necessary and sufficient for uptake of 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) and its azido analog in Escherichia coli

scientific article published on 30 September 2018

Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC.

scientific article published in April 2009

VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa

scientific article published on 21 February 2020

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