List of works - Yijun Chen

A bacterial nitric oxide synthase from a Nocardia species

scientific article published on 01 September 1994

Bifunctional Fusion Proteins Derived from Tumstatin and 4-1BBL for Targeted Cancer Therapy

scientific article published on 28 December 2018

Catalytic Effects of Different Heparin Analogs on the Hydrolysis of Auramine O

scientific article published on 01 January 2011

Chemical Protein Synthesis by Solid Phase Ligation of Unprotected Peptide Segments

article by Lynne E. Canne et al published September 1999 in Journal of the American Chemical Society

Chirality plays critical roles in enhancing the aqueous solubility of nocathiacin I by block copolymer micelles.

scientific article published on 29 July 2012

Cloning, expression, and characterization of a novel diketoreductase from Acinetobacter baylyi.

scientific article published in February 2009

Cooperative down-regulation of ribosomal protein L10 and NF-κB signaling pathway is responsible for the anti-proliferative effects by DMAPT in pancreatic cancer cells

scientific article

Core-modified sordaricin derivatives: synthesis and antifungal activity.

scientific article published in December 2002

Correction to "Bifunctional Fusion Proteins Derived from Tumstatin and 4-1BBL for Targeted Cancer Therapy"

scientific article published on 14 November 2019

Determination of enantiomeric excess of ethyl 3,5-dihydroxy-6-benzyloxy hexanoate by chiral reverse phase high performance liquid chromatography.

scientific article published in January 2008

Directly utilizing an endogenous gene to dissect regulatory elements in the biosynthetic gene cluster of nosiheptide.

scientific article published in September 2014

Discovery of a small molecule targeting SET-PP2A interaction to overcome BCR-ABLT315I mutation of chronic myeloid leukemia

scientific article published in May 2015

Discovery of an Orally Selective Inhibitor of Signal Transducer and Activator of Transcription 3 Using Advanced Multiple Ligand Simultaneous Docking

scientific article published on 28 February 2017

Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase

scientific article

Efficient access to the non-reducing end of low molecular weight heparin for fluorescent labeling.

scientific article published on 21 May 2014

Efficient amplification of genes involved in microbial secondary metabolism by an improved genome walking method

scientific article published on 08 April 2010

Engineering of a UDP-Glycosyltransferase for the Efficient Whole-Cell Biosynthesis of Siamenoside I in <i>Escherichia coli</i>

scientific article published in 2022

Enhancement of biocatalytic efficiency by increasing substrate loading: enzymatic preparation of L-homophenylalanine.

scientific article published on 28 July 2013

Expanding the Catalytic Promiscuity of Heparinase III from Pedobacter heparinus

scientific article

Expression and characterization of human group V phospholipase A2

scientific article

Functional roles of Tryptophan residues in diketoreductase from Acinetobacter baylyi

scientific article published on 01 August 2012

Genetic incorporation of D-lysine into diketoreductase in Escherichia coli cells.

scientific article published on 9 May 2012

Glycyrrhetinic Acid Functionalized Graphene Oxide for Mitochondria Targeting and Cancer Treatment In Vivo

scientific article

Group-specific assays that distinguish between the four major types of mammalian phospholipase A2.

scientific article published on May 1999

Highly specific quantification of microRNA by coupling probe-rolling circle amplification and Förster resonance energy transfer

scientific article published on 10 March 2016

Identification of a heparosan heptasaccharide as an effective anti-inflammatory agent by partial desulfation of low molecular weight heparin

scientific article published on 12 September 2019

Identification of important residues in diketoreductase from Acinetobacter baylyi by molecular modeling and site-directed mutagenesis

scientific article published on 30 August 2011

Identification of truncated form of NosP as a transcription factor to regulate the biosynthesis of nosiheptide.

scientific article

Involucratustones A-C: Unprecedented Sesquiterpene Dimers Containing Multiple Contiguous Quaternary Carbons from Stahlianthus involucratus.

scientific article published on 29 July 2015

MD2 Is a Potential Biomarker Associated with Immune Cell Infiltration in Gliomas

scientific article published on 17 March 2022

Microbial generation of nocathiacin acid from nocathiacin I.

scientific article published on 27 January 2010

Microbial models of soil metabolism: biotransformations of danofloxacin

scientific article published on 01 November 1997

Multiple oxidative routes towards the maturation of nosiheptide.

scientific article published on 12 August 2013

Mutagenesis of NosM Leader Peptide Reveals Important Elements in Nosiheptide Biosynthesis

scientific article published on 2 December 2016

Novel 2-phenyloxypyrimidine derivative induces apoptosis and autophagy via inhibiting PI3K pathway and activating MAPK/ERK signaling in hepatocellular carcinoma cells

scientific article published on 19 July 2018

Oligopeptides as substrates and inhibitors for a new constitutive nitric oxide synthase from rat cerebellum.

scientific article published in July 1996

Olympics may have a negative impact on China's research

scientific article published on 01 August 2008

Optimization of critical medium components for enhancing antibacterial thiopeptide nocathiacin I production with significantly improved quality

scientific article published on 01 April 2017

Oral delivery of exenatide via microspheres prepared by cross-linking of alginate and hyaluronate

scientific article (publication date: 2014)

PhD: routine technical work of sequencing is no substitute.

scientific article published in April 2010

Photoswitchable Heparinase III for Enzymatic Preparation of Low Molecular Weight Heparin

scientific article published on 19 December 2017

Quantitative Assessment of the Absolute Purity of Thiopeptcin Reference Standard by 1H-NMR

scientific article published on 01 January 2018

Recombinant human CD137L for cancer immunotherapy: effects of different fusions and linkers on its activity

scientific article

Riboflavin Is Directly Involved in the N-Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases

scientific article published on 03 April 2020

Ribosomal protein L10 in mitochondria serves as a regulator for ROS level in pancreatic cancer cells

Selection of Reference Genes for Gene Expression Normalization in Peucedanum praeruptorum Dunn under Abiotic Stresses, Hormone Treatments and Different Tissues

scientific article

Separation of structurally similar nocathiacin analogues by reversed phase chromatography

scientific article published on 06 March 2010

Soluble expression of recombinant human CD137 ligand in Escherichia coli by co-expression of chaperones

scientific article published on 15 October 2011

Sordarin oxazepine derivatives as potent antifungal agents.

scientific article published in October 2002

Spirotrichilins A and B: Two Rearranged Spirocyclic Limonoids from Trichilia connaroides.

scientific article published on 7 April 2016

Stereoselective introduction of two chiral centers by a single diketoreductase: an efficient biocatalytic route for the synthesis of statin side chains.

scientific article published on 16 November 2009

The "gate keeper" role of Trp222 determines the enantiopreference of diketoreductase toward 2-chloro-1-phenylethanone

scientific article

The apoptotic effects of toosendanin are partially mediated by activation of deoxycytidine kinase in HL-60 cells

scientific article

The importance of start codon of nosM in nosiheptide production

scientific article published on 01 November 2015

Universal method facilitating the amplification of extremely GC-rich DNA fragments from genomic DNA.

scientific article published in July 2010

List of works by Yijun Chen

A bacterial nitric oxide synthase from a Nocardia species

Bifunctional Fusion Proteins Derived from Tumstatin and 4-1BBL for Targeted Cancer Therapy

Catalytic Effects of Different Heparin Analogs on the Hydrolysis of Auramine O

Chemical Protein Synthesis by Solid Phase Ligation of Unprotected Peptide Segments

Chirality plays critical roles in enhancing the aqueous solubility of nocathiacin I by block copolymer micelles.

Cloning, expression, and characterization of a novel diketoreductase from Acinetobacter baylyi.

Cooperative down-regulation of ribosomal protein L10 and NF-κB signaling pathway is responsible for the anti-proliferative effects by DMAPT in pancreatic cancer cells

Core-modified sordaricin derivatives: synthesis and antifungal activity.

Correction to "Bifunctional Fusion Proteins Derived from Tumstatin and 4-1BBL for Targeted Cancer Therapy"

Determination of enantiomeric excess of ethyl 3,5-dihydroxy-6-benzyloxy hexanoate by chiral reverse phase high performance liquid chromatography.

Directly utilizing an endogenous gene to dissect regulatory elements in the biosynthetic gene cluster of nosiheptide.

Discovery of a small molecule targeting SET-PP2A interaction to overcome BCR-ABLT315I mutation of chronic myeloid leukemia

Discovery of an Orally Selective Inhibitor of Signal Transducer and Activator of Transcription 3 Using Advanced Multiple Ligand Simultaneous Docking

Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase

Efficient access to the non-reducing end of low molecular weight heparin for fluorescent labeling.

Efficient amplification of genes involved in microbial secondary metabolism by an improved genome walking method

Engineering of a UDP-Glycosyltransferase for the Efficient Whole-Cell Biosynthesis of Siamenoside I in <i>Escherichia coli</i>

Enhancement of biocatalytic efficiency by increasing substrate loading: enzymatic preparation of L-homophenylalanine.

Expanding the Catalytic Promiscuity of Heparinase III from Pedobacter heparinus

Expression and characterization of human group V phospholipase A2

Functional roles of Tryptophan residues in diketoreductase from Acinetobacter baylyi

Genetic incorporation of D-lysine into diketoreductase in Escherichia coli cells.

Glycyrrhetinic Acid Functionalized Graphene Oxide for Mitochondria Targeting and Cancer Treatment In Vivo

Group-specific assays that distinguish between the four major types of mammalian phospholipase A2.

Highly specific quantification of microRNA by coupling probe-rolling circle amplification and Förster resonance energy transfer

Identification of a heparosan heptasaccharide as an effective anti-inflammatory agent by partial desulfation of low molecular weight heparin

Identification of important residues in diketoreductase from Acinetobacter baylyi by molecular modeling and site-directed mutagenesis

Identification of truncated form of NosP as a transcription factor to regulate the biosynthesis of nosiheptide.

Involucratustones A-C: Unprecedented Sesquiterpene Dimers Containing Multiple Contiguous Quaternary Carbons from Stahlianthus involucratus.

MD2 Is a Potential Biomarker Associated with Immune Cell Infiltration in Gliomas

Microbial generation of nocathiacin acid from nocathiacin I.

Microbial models of soil metabolism: biotransformations of danofloxacin

Multiple oxidative routes towards the maturation of nosiheptide.

Mutagenesis of NosM Leader Peptide Reveals Important Elements in Nosiheptide Biosynthesis

Novel 2-phenyloxypyrimidine derivative induces apoptosis and autophagy via inhibiting PI3K pathway and activating MAPK/ERK signaling in hepatocellular carcinoma cells

Oligopeptides as substrates and inhibitors for a new constitutive nitric oxide synthase from rat cerebellum.

Olympics may have a negative impact on China's research

Optimization of critical medium components for enhancing antibacterial thiopeptide nocathiacin I production with significantly improved quality

Oral delivery of exenatide via microspheres prepared by cross-linking of alginate and hyaluronate

PhD: routine technical work of sequencing is no substitute.

Photoswitchable Heparinase III for Enzymatic Preparation of Low Molecular Weight Heparin

Quantitative Assessment of the Absolute Purity of Thiopeptcin Reference Standard by 1H-NMR

Recombinant human CD137L for cancer immunotherapy: effects of different fusions and linkers on its activity

Riboflavin Is Directly Involved in the N-Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases

Ribosomal protein L10 in mitochondria serves as a regulator for ROS level in pancreatic cancer cells

Selection of Reference Genes for Gene Expression Normalization in Peucedanum praeruptorum Dunn under Abiotic Stresses, Hormone Treatments and Different Tissues

Separation of structurally similar nocathiacin analogues by reversed phase chromatography

Soluble expression of recombinant human CD137 ligand in Escherichia coli by co-expression of chaperones

Sordarin oxazepine derivatives as potent antifungal agents.

Spirotrichilins A and B: Two Rearranged Spirocyclic Limonoids from Trichilia connaroides.

Stereoselective introduction of two chiral centers by a single diketoreductase: an efficient biocatalytic route for the synthesis of statin side chains.

The "gate keeper" role of Trp222 determines the enantiopreference of diketoreductase toward 2-chloro-1-phenylethanone

The apoptotic effects of toosendanin are partially mediated by activation of deoxycytidine kinase in HL-60 cells

The importance of start codon of nosM in nosiheptide production

Universal method facilitating the amplification of extremely GC-rich DNA fragments from genomic DNA.