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List of works by Paul Brennan

A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine

scientific article published on January 2014

Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression

scientific article published on July 2004

Blinatumomab induces autologous T-cell killing of chronic lymphocytic leukemia cells ⬇️

scientific article published on June 28, 2013

Characterization of intercellular adhesion molecule-1 regulation by Epstein-Barr virus-encoded latent membrane protein-1 identifies pathways that cooperate with nuclear factor kappa B to activate transcription

scientific article published in January 2001

Defining the prognosis of early stage chronic lymphocytic leukaemia patients

scientific article published on 15 December 2011

Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia

scientific article published on 17 March 2014

Epstein-Barr virus induces a distinct form of DNA-bound STAT1 compared with that found in interferon-stimulated B lymphocytes

scientific article published on July 2007

Epstein-Barr virus regulates STAT1 through latent membrane protein 1.

scientific article

Epstein-Barr virus represses the FoxO1 transcription factor through latent membrane protein 1 and latent membrane protein 2A

scientific article

Genetic modification of primary chronic lymphocytic leukemia cells with a lentivirus expressing CD38.

scientific article

Key Molecular Drivers of Chronic Lymphocytic Leukemia

scientific article published on 10 August 2016

Mimicking the tumour microenvironment: three different co‐culture systems induce a similar phenotype but distinct proliferative signals in primary chronic lymphocytic leukaemia cells ⬇️

scientific article published on June 19, 2012

NF-kappaB as a prognostic marker and therapeutic target in chronic lymphocytic leukemia

scientific article published on September 2009

Phosphatidylinositol 3-kinase is essential for the proliferation of lymphoblastoid cells

scientific article published on February 2002

Proteomic profiling of human respiratory epithelia by iTRAQ reveals biomarkers of exposure and harm by tobacco smoke components

scientific article

Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia

scientific article

STAT1 contributes to the maintenance of the latency III viral programme observed in Epstein-Barr virus-transformed B cells and their recognition by CD8+ T cells

scientific article

Susceptibility of B lymphocytes to adenovirus type 5 infection is dependent upon both coxsackie-adenovirus receptor and alphavbeta5 integrin expression

scientific article

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

scientific article

The novel nuclear factor-kappaB inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine

scientific article

Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2.

scientific article

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