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List of works by Xing Chang

A new role for CD28 in the survival of autoreactive T cells in the periphery after chronic exposure to autoantigen

scientific article published on 16 August 2004

B7-CD28 interaction promotes proliferation and survival but suppresses differentiation of CD4-CD8- T cells in the thymus.

scientific article

B7-deficient autoreactive T cells are highly susceptible to suppression by CD4(+)CD25(+) regulatory T cells.

scientific article published in February 2007

Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity

scientific article published on 01 July 2006

Cytokine-induced killer T cells kill immature dendritic cells by TCR-independent and perforin-dependent mechanisms

scientific article published on 22 September 2006

Cytopenia and autoimmune diseases: a vicious cycle fueled by mTOR dysregulation in hematopoietic stem cells.

scientific article published on February 2013

Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells

scientific article published on 13 June 2017

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells

scientific article published on 13 January 2014

FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2.

scientific article

Foxp3 controls autoreactive T cell activation through transcriptional regulation of early growth response genes and E3 ubiquitin ligase genes, independently of thymic selection

scientific journal article

Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase

scientific article published on 04 October 2018

Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells

scientific article

Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production

scientific article published on 26 June 2018

KDM4 Orchestrates Epigenomic Remodeling of Senescent Cells and Potentiates the Senescence-Associated Secretory Phenotype

scientific article published on 13 May 2021

MEKK3 is essential for lymphopenia-induced T cell proliferation and survival.

scientific article

RNA-binding protein hnRNPLL as a critical regulator of lymphocyte homeostasis and differentiation

scientific article

RNA-binding protein hnRNPLL regulates mRNA splicing and stability during B-cell to plasma-cell differentiation

scientific article

Single-cell RNA-Seq analysis identifies a noncoding RNA that post-transcriptionally up-regulates IL-4 production in T helper cells

scientific article published in Journal of Biological Chemistry

Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells

scientific article

Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility

scientific article

The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis

scientific journal article

The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation.

scientific article published on 17 February 2011

Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss.

scientific article published on 26 September 2017

Tumor growth impedes natural-killer-cell maturation in the bone marrow.

scientific article published on 23 March 2006

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