List of works - Kenichi Masumura

Acrylamide genotoxicity in young versus adult gpt delta male rats

scientific article published on 25 March 2011

Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages

scientific article

Antigenotoxic effects of p53 on spontaneous and ultraviolet light B--induced deletions in the epidermis of gpt delta transgenic mice.

scientific article

Chemopreventive effects of silymarin against 1,2-dimethylhydrazine plus dextran sodium sulfate-induced inflammation-associated carcinogenicity and genotoxicity in the colon of gpt delta rats.

scientific article published on 28 July 2011

Combined ascorbic acid and sodium nitrite treatment induces oxidative DNA damage-associated mutagenicity in vitro, but lacks initiation activity in rat forestomach epithelium.

scientific article published on 22 April 2008

Combined genotoxic effects of radiation and a tobacco-specific nitrosamine in the lung of gpt delta transgenic mice.

scientific article published on 7 September 2006

Deletion and single nucleotide substitution at G:C in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment.

scientific article published on 22 August 2006

Differential effects of low- and high-dose X-rays on N-ethyl-N-nitrosourea-induced mutagenesis in thymocytes of B6C3F1 gpt-delta mice.

scientific article

Dose-dependent de novo germline mutations detected by whole-exome sequencing in progeny of ENU-treated male gpt delta mice.

scientific article published on 28 September 2016

Effect ofAtmDisruption on Spontaneously Arising and Radiation-Induced Deletion Mutations in Mouse Liver

scientific article published on November 1, 2003

Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice

scientific article published on 01 June 2007

Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice

scientific article published on April 2016

Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays

scientific article published on 18 September 2013

Evaluation of the genotoxicity of tamoxifen in the liver and kidney of F344 gpt delta transgenic rat in 3-week and 13-week repeated dose studies.

scientific article published on 30 July 2013

Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens

scientific article

Further characterization and validation of gpt delta transgenic mice for quantifying somatic mutations in vivo.

scientific article

Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents

scientific article published on December 2015

Genotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studies.

scientific article published on 15 July 2014

Heavy-ion-induced mutations in the gpt delta transgenic mouse: comparison of mutation spectra induced by heavy-ion, X-ray, and gamma-ray radiation.

scientific article

Heavy-ion-induced mutations in the gpt delta transgenic mouse: effect of p53 gene knockout

scientific article published on 01 January 2002

In vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C.

scientific article published on 7 October 2014

Involvement of mismatch repair proteins in adaptive responses induced by N-methyl-N'-nitro-N-nitrosoguanidine against γ-induced genotoxicity in human cells.

scientific article published on 15 June 2011

Lack of in vivo mutagenicity and oxidative DNA damage by flumequine in the livers of gpt delta mice.

scientific article published on 27 June 2006

Limited ability of DNA polymerase kappa to suppress benzo[a]pyrene-induced genotoxicity in vivo.

scientific article published on 27 October 2017

Low dose genotoxicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in gpt delta transgenic mice ⬇️

scientific article published on November 10, 2003

Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens.

scientific article

Mutations in the lungs of gpt delta transgenic mice following inhalation of diesel exhaust.

scientific article

New insight into intrachromosomal deletions induced by chrysotile in the gpt delta transgenic mutation assay

scientific article

Novel transgenic rat for in vivo genotoxicity assays using 6-thioguanine and Spi- selection.

scientific article published in January 2003

Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats

scientific journal article

Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse.

scientific article published on 11 September 2003

Radiation dose-rate effect on mutation induction in spleen and liver of gpt delta mice

scientific article published on 01 February 2010

Recent advances in the protocols of transgenic mouse mutation assays.

scientific article

Role of p53 in the progression from ochratoxin A-induced DNA damage to gene mutations in the kidneys of mice

scientific article published on 29 January 2015

Transgenic rat models for mutagenesis and carcinogenesis

scientific article (publication date: 2017)

List of works by Kenichi Masumura

Acrylamide genotoxicity in young versus adult gpt delta male rats

Alterations in the mutagenicity and mutation spectrum induced by benzo[a]pyrene instilled in the lungs of gpt delta mice of various ages

Antigenotoxic effects of p53 on spontaneous and ultraviolet light B--induced deletions in the epidermis of gpt delta transgenic mice.

Chemopreventive effects of silymarin against 1,2-dimethylhydrazine plus dextran sodium sulfate-induced inflammation-associated carcinogenicity and genotoxicity in the colon of gpt delta rats.

Combined ascorbic acid and sodium nitrite treatment induces oxidative DNA damage-associated mutagenicity in vitro, but lacks initiation activity in rat forestomach epithelium.

Combined genotoxic effects of radiation and a tobacco-specific nitrosamine in the lung of gpt delta transgenic mice.

Deletion and single nucleotide substitution at G:C in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment.

Differential effects of low- and high-dose X-rays on N-ethyl-N-nitrosourea-induced mutagenesis in thymocytes of B6C3F1 gpt-delta mice.

Dose-dependent de novo germline mutations detected by whole-exome sequencing in progeny of ENU-treated male gpt delta mice.

Effect ofAtmDisruption on Spontaneously Arising and Radiation-Induced Deletion Mutations in Mouse Liver

Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice

Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice

Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays

Evaluation of the genotoxicity of tamoxifen in the liver and kidney of F344 gpt delta transgenic rat in 3-week and 13-week repeated dose studies.

Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens

Further characterization and validation of gpt delta transgenic mice for quantifying somatic mutations in vivo.

Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents

Genotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studies.

Heavy-ion-induced mutations in the gpt delta transgenic mouse: comparison of mutation spectra induced by heavy-ion, X-ray, and gamma-ray radiation.

Heavy-ion-induced mutations in the gpt delta transgenic mouse: effect of p53 gene knockout

In vivo evidence that DNA polymerase kappa is responsible for error-free bypass across DNA cross-links induced by mitomycin C.

Involvement of mismatch repair proteins in adaptive responses induced by N-methyl-N'-nitro-N-nitrosoguanidine against γ-induced genotoxicity in human cells.

Lack of in vivo mutagenicity and oxidative DNA damage by flumequine in the livers of gpt delta mice.

Limited ability of DNA polymerase kappa to suppress benzo[a]pyrene-induced genotoxicity in vivo.

Low dose genotoxicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in gpt delta transgenic mice ⬇️

Molecular nature of intrachromosomal deletions and base substitutions induced by environmental mutagens.

Mutations in the lungs of gpt delta transgenic mice following inhalation of diesel exhaust.

New insight into intrachromosomal deletions induced by chrysotile in the gpt delta transgenic mutation assay

Novel transgenic rat for in vivo genotoxicity assays using 6-thioguanine and Spi- selection.

Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats

Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse.

Radiation dose-rate effect on mutation induction in spleen and liver of gpt delta mice

Recent advances in the protocols of transgenic mouse mutation assays.

Role of p53 in the progression from ochratoxin A-induced DNA damage to gene mutations in the kidneys of mice

Transgenic rat models for mutagenesis and carcinogenesis