List of works - Jiezhong Chen

A high-dose Shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: underlying mechanism

scientific article

A novel schedule of erlotinib/capecitabine (7/7) as salvage therapy in previously treated advanced pancreatic adenocarcinoma: a case series

scientific article published on March 2016

Activation of PI3K/Akt/mTOR pathway and dual inhibitors of PI3K and mTOR in endometrial cancer

scientific article published on January 2014

Activation of T-regulatory cells by a synbiotic may be important for its anti-inflammatory effect

scientific article published on 01 December 2019

Activation of p53 for the treatment of cancer

scientific article published in July 2009

Activation of signal pathways and the resistance to anti-EGFR treatment in colorectal cancer

scientific article published on December 2010

Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics

scientific article published on 24 July 2013

Approach to multiple pulmonary nodules: a case report and review of literature.

scientific article published on 5 April 2011

Association of human papillomavirus with Fanconi anemia promotes carcinogenesis in Fanconi anemia patients

scientific article published on 17 March 2015

Beta-glucans in the treatment of diabetes and associated cardiovascular risks.

scientific article published on January 2008

Biochemistry and molecular biology of exocellular fungal beta-(1,3)- and beta-(1,6)-glucanases.

scientific article published on March 2007

Calcium prevents retinoic acid-induced disruption of the spectrin-based cytoskeleton in keratinocytes through the Src/PI3K-p85α/AKT/PKCδ/β-adducin pathways.

scientific article

Co-delivery of siRNAs and anti-cancer drugs using layered double hydroxide nanoparticles

scientific article published on 20 January 2014

Development and function of IL-10 IFN-gamma-secreting CD4(+) T cells.

scientific article published on 09 September 2009

Diet high in oat β-glucan activates the gut-hypothalamic (PYY₃₋₃₆-NPY) axis and increases satiety in diet-induced obesity in mice

scientific article published on 20 June 2011

Dissecting the signaling pathways that mediate cancer in PTEN and LKB1 double-knockout mice

scientific article published on September 2015

Downregulation of male-specific cytochrome P450s 2C11 and 3A2 in bile duct–ligated male rats: Importance to reduced hepatic content of cytochrome P450 in cholestasis ⬇️

scientific article published on 01 August 1995

Editorial: Signalling Pathways in Virus-caused Cancers.

scientific article published in January 2017

Effects of bile duct ligation on hepatic expression of female-specific CYP2C12 in male and female rats† ⬇️

scientific article published on September 1, 1998

Effects of simvastatin and 6-hydroxydopamine on histaminergic H1 receptor binding density in rat brains

scientific article published on 14 August 2010

Four major factors regulate phosphatidylinositol 3-kinase signaling pathway in cancers induced by infection of human papillomaviruses

scientific article published on January 2014

Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway

scientific article published on 30 April 2015

HPV-p53-miR-34a axis in HPV-associated cancers

scientific article

Hexarelin Protects Rodent Pancreatic Β-Cells Function from Cytotoxic Effects of Streptozotocin Involving Mitochondrial Signalling Pathways In Vivo and In Vitro

scientific article

High fat diet-induced obesity increases the formation of colon polyps induced by azoxymethane in mice

scientific article published on April 2015

High-fat diet decreases tyrosine hydroxylase mRNA expression irrespective of obesity susceptibility in mice

scientific article published on 11 March 2009

Human papillomavirus 16-encoded E7 protein inhibits IFN-γ-mediated MHC class I antigen presentation and CTL-induced lysis by blocking IRF-1 expression in mouse keratinocytes.

scientific article published on 16 August 2013

Identification of CYP2C9*2 allele in HepG2 cell line.

scientific article published on January 2006

Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases

scientific article

Inflammation-Modulating Effect of Butyrate in the Prevention of Colon Cancer by Dietary Fiber

scientific article published on 17 May 2018

Influenza virus antigenic variation, host antibody production and new approach to control epidemics

scientific article

Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29.

scientific article

Insulin decreases therapeutic efficacy in colon cancer cell line HT29 via the activation of the PI3K/Akt pathway

scientific article published on June 2011

Insulin induces drug resistance in melanoma through activation of the PI3K/Akt pathway

scientific article published on 17 February 2014

Interaction of gut microbiota with dysregulation of bile acids in the pathogenesis of nonalcoholic fatty liver disease and potential therapeutic implications of probiotics

scientific article published on 15 November 2018

Is Src the key to understanding metastasis and developing new treatments for colon cancer?

scientific article published on 13 May 2008

Medicinal importance of fungal beta-(1-->3), (1-->6)-glucans.

scientific article published on 7 March 2007

MicroRNAs, signaling pathways and diseases

scientific article published on December 2015

Mitochondria could be a potential key mediator linking the intestinal microbiota to depression

scientific article published on 05 August 2019

Molecular Mechanisms of Antipsychotic Drug-Induced Diabetes

scientific article published on 21 November 2017

Molecular basis of pathogenesis, prognosis and therapy in chronic lymphocytic leukaemia.

scientific article

Multiple signal pathways in obesity-associated cancer ⬇️

scientific article published on August 22, 2011

Multiple signal pathways in the leukemogenesis and therapeutic implications.

scientific article published on June 2007

Nanotechnology in the management of cervical cancer

scientific article

Nuclear receptors, bile-acid detoxification, and cholestasis

scientific article published in February 2006

Obesity and melanoma: exploring molecular links

scientific article published on September 2013

Osteocyte-induced angiogenesis via VEGF-MAPK-dependent pathways in endothelial cells.

scientific article published on 27 October 2013

PI3K/Akt/mTOR pathway dual inhibitor BEZ235 suppresses the stemness of colon cancer stem cells.

scientific article published on 24 September 2015

Papillomavirus virus like particle-based therapeutic vaccine against human papillomavirus infection related diseases: immunological problems and future directions.

scientific article published on 12 March 2011

Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK.

scientific article

Signaling pathways in HPV-associated cancers and therapeutic implications.

scientific article

Still lots to learn about human papillomaviruses.

scientific article published in March 2015

TAS-102 an Emerging Oral Fluoropyrimidine

scientific article published on January 2016

The Key Role of Mitochondrial Apoptotic Pathway in the Cytotoxic Effect of Mushroom Extracts on Cancer Cells

scientific article published on January 2015

The Role of Butyrate in Attenuating Pathobiont-Induced Hyperinflammation

scientific article published on 04 February 2020

The Src/PI3K/Akt signal pathway may play a key role in decreased drug efficacy in obesity-associated cancer

scientific article published on 01 May 2010

The double life of RIPK1.

scientific article published on 26 May 2015

The effects of diets enriched in beta-glucans on blood lipoprotein concentrations ⬇️

scientific article published on May 5, 2009

The key regulatory roles of the PI3K/Akt signaling pathway in the functionalities of mesenchymal stem cells and applications in tissue regeneration

scientific article published on 10 July 2013

The possible role of IL-17 in obesity-associated cancer.

scientific article

The role of CYP3A4 in the biotransformation of bile acids and therapeutic implication for cholestasis

scientific article

The role of Src in colon cancer and its therapeutic implications

scientific article

The role of interferon gamma in regulation of CD4+ T-cells and its clinical implications.

scientific article published on 10 October 2008

The signal pathways in azoxymethane-induced colon cancer and preventive implications

scientific article published on 11 July 2009

The vermiform appendix: an immunological organ sustaining a microbiome inoculum

scientific article published on 03 January 2019

Unique Effects of Acute Aripiprazole Treatment on the Dopamine D2 Receptor Downstream cAMP-PKA and Akt-GSK3β Signalling Pathways in Rats

scientific article

β-Adducin siRNA disruption of the spectrin-based cytoskeleton in differentiating keratinocytes prevented by calcium acting through calmodulin/epidermal growth factor receptor/cadherin pathway

scientific article published on 7 October 2014

List of works by Jiezhong Chen

A high-dose Shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: underlying mechanism

A novel schedule of erlotinib/capecitabine (7/7) as salvage therapy in previously treated advanced pancreatic adenocarcinoma: a case series

Activation of PI3K/Akt/mTOR pathway and dual inhibitors of PI3K and mTOR in endometrial cancer

Activation of T-regulatory cells by a synbiotic may be important for its anti-inflammatory effect

Activation of p53 for the treatment of cancer

Activation of signal pathways and the resistance to anti-EGFR treatment in colorectal cancer

Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics

Approach to multiple pulmonary nodules: a case report and review of literature.

Association of human papillomavirus with Fanconi anemia promotes carcinogenesis in Fanconi anemia patients

Beta-glucans in the treatment of diabetes and associated cardiovascular risks.

Biochemistry and molecular biology of exocellular fungal beta-(1,3)- and beta-(1,6)-glucanases.

Calcium prevents retinoic acid-induced disruption of the spectrin-based cytoskeleton in keratinocytes through the Src/PI3K-p85α/AKT/PKCδ/β-adducin pathways.

Co-delivery of siRNAs and anti-cancer drugs using layered double hydroxide nanoparticles

Development and function of IL-10 IFN-gamma-secreting CD4(+) T cells.

Diet high in oat β-glucan activates the gut-hypothalamic (PYY₃₋₃₆-NPY) axis and increases satiety in diet-induced obesity in mice

Dissecting the signaling pathways that mediate cancer in PTEN and LKB1 double-knockout mice

Downregulation of male-specific cytochrome P450s 2C11 and 3A2 in bile duct–ligated male rats: Importance to reduced hepatic content of cytochrome P450 in cholestasis ⬇️

Editorial: Signalling Pathways in Virus-caused Cancers.

Effects of bile duct ligation on hepatic expression of female-specific CYP2C12 in male and female rats† ⬇️

Effects of simvastatin and 6-hydroxydopamine on histaminergic H1 receptor binding density in rat brains

Four major factors regulate phosphatidylinositol 3-kinase signaling pathway in cancers induced by infection of human papillomaviruses

Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway

HPV-p53-miR-34a axis in HPV-associated cancers

Hexarelin Protects Rodent Pancreatic Β-Cells Function from Cytotoxic Effects of Streptozotocin Involving Mitochondrial Signalling Pathways In Vivo and In Vitro

High fat diet-induced obesity increases the formation of colon polyps induced by azoxymethane in mice

High-fat diet decreases tyrosine hydroxylase mRNA expression irrespective of obesity susceptibility in mice

Human papillomavirus 16-encoded E7 protein inhibits IFN-γ-mediated MHC class I antigen presentation and CTL-induced lysis by blocking IRF-1 expression in mouse keratinocytes.

Identification of CYP2C9*2 allele in HepG2 cell line.

Implications of ghrelin and hexarelin in diabetes and diabetes-associated heart diseases

Inflammation-Modulating Effect of Butyrate in the Prevention of Colon Cancer by Dietary Fiber

Influenza virus antigenic variation, host antibody production and new approach to control epidemics

Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29.

Insulin decreases therapeutic efficacy in colon cancer cell line HT29 via the activation of the PI3K/Akt pathway

Insulin induces drug resistance in melanoma through activation of the PI3K/Akt pathway

Interaction of gut microbiota with dysregulation of bile acids in the pathogenesis of nonalcoholic fatty liver disease and potential therapeutic implications of probiotics

Is Src the key to understanding metastasis and developing new treatments for colon cancer?

Medicinal importance of fungal beta-(1-->3), (1-->6)-glucans.

MicroRNAs, signaling pathways and diseases

Mitochondria could be a potential key mediator linking the intestinal microbiota to depression

Molecular Mechanisms of Antipsychotic Drug-Induced Diabetes

Molecular basis of pathogenesis, prognosis and therapy in chronic lymphocytic leukaemia.

Multiple signal pathways in obesity-associated cancer ⬇️

Multiple signal pathways in the leukemogenesis and therapeutic implications.

Nanotechnology in the management of cervical cancer

Nuclear receptors, bile-acid detoxification, and cholestasis

Obesity and melanoma: exploring molecular links

Osteocyte-induced angiogenesis via VEGF-MAPK-dependent pathways in endothelial cells.

PI3K/Akt/mTOR pathway dual inhibitor BEZ235 suppresses the stemness of colon cancer stem cells.

Papillomavirus virus like particle-based therapeutic vaccine against human papillomavirus infection related diseases: immunological problems and future directions.

Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK.

Signaling pathways in HPV-associated cancers and therapeutic implications.

Still lots to learn about human papillomaviruses.

TAS-102 an Emerging Oral Fluoropyrimidine

The Key Role of Mitochondrial Apoptotic Pathway in the Cytotoxic Effect of Mushroom Extracts on Cancer Cells

The Role of Butyrate in Attenuating Pathobiont-Induced Hyperinflammation

The Src/PI3K/Akt signal pathway may play a key role in decreased drug efficacy in obesity-associated cancer

The double life of RIPK1.

The effects of diets enriched in beta-glucans on blood lipoprotein concentrations ⬇️

The key regulatory roles of the PI3K/Akt signaling pathway in the functionalities of mesenchymal stem cells and applications in tissue regeneration

The possible role of IL-17 in obesity-associated cancer.

The role of CYP3A4 in the biotransformation of bile acids and therapeutic implication for cholestasis

The role of Src in colon cancer and its therapeutic implications

The role of interferon gamma in regulation of CD4+ T-cells and its clinical implications.

The signal pathways in azoxymethane-induced colon cancer and preventive implications

The vermiform appendix: an immunological organ sustaining a microbiome inoculum

Unique Effects of Acute Aripiprazole Treatment on the Dopamine D2 Receptor Downstream cAMP-PKA and Akt-GSK3β Signalling Pathways in Rats

β-Adducin siRNA disruption of the spectrin-based cytoskeleton in differentiating keratinocytes prevented by calcium acting through calmodulin/epidermal growth factor receptor/cadherin pathway