List of works - Sophie Tartare-Deckert

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

scientific article published on 15 April 2021

A feed-forward mechanosignaling loop confers resistance to therapies targeting the MAPK pathway in BRAF-mutant melanoma

scientific article published on 16 March 2020

A non-coding function of TYRP1 mRNA promotes melanoma growth.

scientific article

Blockade of the pro-fibrotic reaction mediated by the miR-143/-145 cluster enhances the responses to targeted therapy in melanoma

scientific article published on 14 February 2022

Cherubism allele heterozygosity amplifies microbe-induced inflammatory responses in murine macrophages

scientific article published on 23 February 2015

Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma

scientific article published on 2 May 2017

Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro

scientific article

Gene expression profiling of normal human pulmonary fibroblasts following coculture with non-small-cell lung cancer cells reveals alterations related to matrix degradation, angiogenesis, cell growth and survival

article

HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.

scientific article

Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells

scientific article published on 26 September 2011

Identification by mutation of the tyrosine residues in the insulin receptor substrate-1 affecting association with the tyrosine phosphatase 2C and phosphatidylinositol 3-kinase

scientific article published on 01 December 1995

In vitro and in vivo anti-melanoma effects of ciglitazone.

scientific article

LIF mediates proinvasive activation of stromal fibroblasts in cancer

scientific article

Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation

scientific article

Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner.

scientific article published on 5 June 2013

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

scientific article

Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment

scientific article

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

scientific article published on 23 November 2010

Prostaglandin E2 induces interaction between hSlo potassium channel and Syk tyrosine kinase in osteosarcoma cells.

scientific article

Regulation of secreted protein acidic and rich in cysteine during adipose conversion and adipose tissue hyperplasia.

scientific article published on November 2006

Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1

scientific article published on 23 January 2020

Risk for nevus transformation and melanoma proliferation and invasion during natalizumab treatment: four years of dermoscopic follow-up with immunohistological studies and proliferation and invasion assays

scientific article

SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness

scientific article published on 8 December 2015

SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival.

scientific article published on 20 June 2011

SPARC represses E-cadherin and induces mesenchymal transition during melanoma development

scientific article published on August 2006

Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

scientific article published on December 2012

Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest

scientific article published on 17 March 2009

Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma

scientific article published on 27 December 2021

Technical advance: actin CytoFRET, a novel FRET flow cytometry method for detection of actin dynamics in resting and activated T cell.

scientific article published on 21 June 2013

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion

scientific article

The matricellular protein SPARC/osteonectin as a newly identified factor up-regulated in obesity.

scientific article published on 09 April 2001

The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

scientific article

The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression.

scientific article

Tumor-Derived Fibronectin Is Involved in Melanoma Cell Invasion and Regulated by V600E B-Raf Signaling Pathway

scientific article published on 07 September 2006

Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis

scientific article published on 30 April 2015

Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway

scientific article published on 21 February 2002

Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte

scientific article (publication date: 15 June 2001)

[Melanoma therapeutic escape: the biomechanical track]

scientific article published on 05 November 2020

List of works by Sophie Tartare-Deckert

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

A feed-forward mechanosignaling loop confers resistance to therapies targeting the MAPK pathway in BRAF-mutant melanoma

A non-coding function of TYRP1 mRNA promotes melanoma growth.

Blockade of the pro-fibrotic reaction mediated by the miR-143/-145 cluster enhances the responses to targeted therapy in melanoma

Cherubism allele heterozygosity amplifies microbe-induced inflammatory responses in murine macrophages

Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma

Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro

Gene expression profiling of normal human pulmonary fibroblasts following coculture with non-small-cell lung cancer cells reveals alterations related to matrix degradation, angiogenesis, cell growth and survival

HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.

Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells

Identification by mutation of the tyrosine residues in the insulin receptor substrate-1 affecting association with the tyrosine phosphatase 2C and phosphatidylinositol 3-kinase

In vitro and in vivo anti-melanoma effects of ciglitazone.

LIF mediates proinvasive activation of stromal fibroblasts in cancer

Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation

Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner.

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

Pathological prion protein exposure switches on neuronal mitogen-activated protein kinase pathway resulting in microglia recruitment

Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.

Prostaglandin E2 induces interaction between hSlo potassium channel and Syk tyrosine kinase in osteosarcoma cells.

Regulation of secreted protein acidic and rich in cysteine during adipose conversion and adipose tissue hyperplasia.

Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1

Risk for nevus transformation and melanoma proliferation and invasion during natalizumab treatment: four years of dermoscopic follow-up with immunohistological studies and proliferation and invasion assays

SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness

SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival.

SPARC represses E-cadherin and induces mesenchymal transition during melanoma development

Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest

Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma

Technical advance: actin CytoFRET, a novel FRET flow cytometry method for detection of actin dynamics in resting and activated T cell.

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion

The matricellular protein SPARC/osteonectin as a newly identified factor up-regulated in obesity.

The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression.

Tumor-Derived Fibronectin Is Involved in Melanoma Cell Invasion and Regulated by V600E B-Raf Signaling Pathway

Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis

Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway

Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte

[Melanoma therapeutic escape: the biomechanical track]