List of works - Grażyna Kwapiszewska

A Twist on Pulmonary Vascular Remodeling: Endothelial to Mesenchymal Transition?

scientific article published in February 2018

Amitriptyline and carbamazepine utilize voltage-gated ion channel suppression to impair excitability of sensory dorsal horn neurons in thin tissue slice: An in vitro study

scientific article published on 2 March 2016

Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury

scientific article published on 22 December 2016

Aquaporin 1 controls the functional phenotype of pulmonary smooth muscle cells in hypoxia-induced pulmonary hypertension

scientific article published on 13 April 2017

BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension

scientific article published on 8 October 2012

Basement Membrane Remodelling Controls Endothelial Function in IPAH

scientific article published on 11 March 2020

Biomarkers for Pulmonary Vascular Remodeling in Systemic Sclerosis: A Pathophysiological Approach.

scientific article published on 19 June 2018

CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis

scientific article published on 02 July 2020

Characterization of platelet-specific mRNA by real-time PCR after laser-assisted microdissection

scientific article

Cofilin, a hypoxia-regulated protein in murine lungs identified by 2DE: role of the cytoskeletal protein cofilin in pulmonary hypertension

scientific article

Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients

scientific article published on 3 April 2015

Comprehensive analysis of inflammatory markers in chronic thromboembolic pulmonary hypertension patients

scientific article

Disconnect between Fibrotic Response and Right Ventricular Dysfunction

scientific article published on 01 June 2019

Distinct differences in gene expression patterns in pulmonary arteries of patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis with pulmonary hypertension.

scientific article

Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation

scientific article published on 20 September 2018

Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension

scientific article

Dysregulated Bone Morphogenetic Protein Signaling in Monocrotaline-Induced Pulmonary Arterial Hypertension

scientific article published on 08 March 2007

Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.

scientific article

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

scientific article published on 27 April 2019

Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration

scientific article published on 21 December 2016

Editorial: Molecular Mechanisms in Pulmonary Hypertension and Right Ventricle Dysfunction

scientific article published on 10 December 2018

Editorial: Multitasking Biomolecules in Human Pathologies: Known Players on Their Unexpected Journeys

scientific article published on 21 August 2020

Endothelial Basement Membrane Components and Their Products, Matrikines: Active Drivers of Pulmonary Hypertension?

scientific article published on 03 September 2020

Endothelial Dysfunction Following Enhanced TMEM16A Activity in Human Pulmonary Arteries

scientific article published on 28 August 2020

Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.

scientific article published on 10 July 2014

Expression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertension

scientific article

FHL-1 is not involved in pressure overload-induced maladaptive right ventricular remodeling and dysfunction

scientific article published on 24 January 2020

Fhl-1, a new key protein in pulmonary hypertension.

scientific article

Forschung in Österreich – das Ludwig Boltzmann Institut für Lungengefäßforschung

scientific article published on 11 May 2016

Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner

Functional and molecular factors associated with TAPSE in hypoxic pulmonary hypertension.

scientific article published on 22 April 2016

High-mobility group box-1 induces vascular remodelling processes via c-Jun activation

scientific article published on 28 February 2015

Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure

scientific article published on 01 October 2019

Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia

scientific article published on 27 October 2006

Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.

scientific article published on 18 September 2014

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.

scientific article

Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

scientific article published on 20 July 2017

IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis

scientific article published on 29 September 2019

Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

scientific article published on 01 December 2020

Identification of proteins in laser-microdissected small cell numbers by SELDI-TOF and Tandem MS

scientific article

Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling.

scientific article published on 27 January 2014

Impact of TASK-1 in Human Pulmonary Artery Smooth Muscle Cells

scientific article published on 30 March 2006

Importance of kynurenine in pulmonary hypertension.

scientific article published on 13 July 2017

Increased S100A4 expression in the vasculature of human COPD lungs and murine model of smoke-induced emphysema

scientific article published on 20 October 2015

Inducible NOS Inhibition Reverses Tobacco-Smoke-Induced Emphysema and Pulmonary Hypertension in Mice

scientific article published on 01 October 2011

Inhibiting eicosanoid degradation exerts antifibrotic effects in a pulmonary fibrosis mouse model and human tissue

scientific article published on 05 December 2019

Kinases as potential targets for treatment of pulmonary hypertension and right ventricular dysfunction

scientific article published on 10 November 2019

LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension

scientific article published on 22 March 2019

Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia

scientific article published on 21 February 2017

Laser Capture Microdissection of Tissue Sections for High-Throughput RNA Analysis.

scientific article published in January 2017

Laser-microdissection for cell type- and compartment-specific analyses on genomic and proteomic level

scientific article

Lessons from Transcriptomics in Hypoxia Induced Pulmonary Hypertension: Does the Mouse Strain Matter?

scientific article published on 01 January 2019

Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1

scientific article published on 16 January 2019

Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores

scientific article published on 11 December 2019

Machine Learning Analysis of the Bleomycin Mouse Model Reveals the Compartmental and Temporal Inflammatory Pulmonary Fingerprint

scientific article published on 18 November 2020

Meprin β contributes to collagen deposition in lung fibrosis

scientific article published on 6 January 2017

Meprinβ, a novel mediator of vascular remodelling underlying pulmonary hypertension

scientific article published on 31 January 2014

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis

scientific article published on 05 July 2019

Metformin induces lipogenic differentiation in myofibroblasts to reverse mouse and human lung fibrosis

Microarray analysis in pulmonary hypertension

scientific article

NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension

scientific article

Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.

scientific article

No indication of insulin resistance in idiopathic PAH with preserved physical activity

scientific article published on 26 March 2020

Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction.

scientific article published in June 2017

Origin of neomuscularized vessels in mice exposed to chronic hypoxia.

scientific article

PAR-2 inhibition reverses experimental pulmonary hypertension.

scientific article

PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis

scientific article published on 05 February 2020

Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018

article

Peroxisome proliferator-activated receptor-β/δ, the acute signaling factor in prostacyclin-induced pulmonary vasodilation

scientific article published on 20 October 2011

Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature

scientific article

Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy

scientific article

Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors

scientific article published in February 2017

Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography

scientific article published in April 2015

Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells - potential role in lung fibrosis.

scientific article published on 6 June 2013

RFLP analysis of 1-aminocyclopropane-1-carboxylate synthase ACC2 and ACC4 genes from Polish cultivars of tomato

scientific article published on 01 January 2002

Receptor for Activated C-Kinase 1, a Novel Interaction Partner of Type II Bone Morphogenetic Protein Receptor, Regulates Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension

scientific article published on 21 May 2007

Resident cell lineages are preserved in pulmonary vascular remodeling

scientific article

Right ventricular fibrosis and dysfunction: Actual concepts and common misconceptions.

scientific article published on 14 January 2018

Role of protease-activated receptor-2 in idiopathic pulmonary fibrosis.

scientific article published on 11 March 2011

Role of the Aryl Hydrocarbon Receptor/ARNT/Cytochrome P450 System in Pulmonary Vascular Diseases

scientific article published on 26 June 2019

Shroom expression is attenuated in pulmonary arterial hypertension.

scientific article

Single-cell transcriptomics reveals skewed cellular communication and phenotypic shift in pulmonary artery remodeling

scientific article published in 2022

Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries.

scientific article

Stiffness of the Extracellular Matrix: A Regulator of Prostaglandins in Pulmonary Fibrosis?

scientific article published on 18 September 2020

Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair

scientific article

Systematic comparison of the T7-IVT and SMART-based RNA preamplification techniques for DNA microarray experiments

scientific article

TASK-1 (KCNK3) channels in the lung: from cell biology to clinical implications.

scientific article published on 9 November 2017

TGF-β1 induces tissue factor expression in human lung fibroblasts in a PI3K/JNK/Akt-dependent and AP-1-dependent manner

scientific article published on 05 July 2012

TMEM16A Potentiation: Possible Drawbacks

scientific article published on 28 May 2020

TWIST1 Drives Smooth Muscle Cell Proliferation in Pulmonary Hypertension via Loss of GATA-6 and BMPR2

scientific article published on 21 July 2020

Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic PAH

scientific article published on 25 April 2019

The Role of Proteinase-activated Receptor-2 in Idiopathic Pulmonary Fibrosis: Is There Really Novel Therapeutic Potential Here?

The inflammatory cell landscape in the lungs of patients with idiopathic pulmonary arterial hypertension.

scientific article published on 25 January 2018

The transforming growth factor- /Smad2,3 signalling axis is impaired in experimental pulmonary hypertension

scientific article published on 28 March 2007

Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis

scientific article published on 22 November 2018

Translationally Controlled Tumor Protein in Extracellular Vehicles: Dangerous Cargo?

scientific article published on 01 October 2018

Treprostinil inhibits the recruitment of bone marrow-derived circulating fibrocytes in chronic hypoxic pulmonary hypertension.

scientific article published on 4 June 2010

Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis

scientific article published on 01 April 2017

Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis.

scientific article published on 14 November 2016

[Epigenetics and genetics of pulmonary arterial hypertension--new insights from the last years].

scientific article published on 9 December 2014

[Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016].

scientific article published on 19 October 2016

[Pulmonary (Arterial) Hypertension].

scientific article

[Pulmonary arterial hypertension--a disease of the immune system?].

scientific article published on 9 December 2014

List of works by Grażyna Kwapiszewska

A Twist on Pulmonary Vascular Remodeling: Endothelial to Mesenchymal Transition?

Amitriptyline and carbamazepine utilize voltage-gated ion channel suppression to impair excitability of sensory dorsal horn neurons in thin tissue slice: An in vitro study

Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury

Aquaporin 1 controls the functional phenotype of pulmonary smooth muscle cells in hypoxia-induced pulmonary hypertension

BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension

Basement Membrane Remodelling Controls Endothelial Function in IPAH

Biomarkers for Pulmonary Vascular Remodeling in Systemic Sclerosis: A Pathophysiological Approach.

CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis

Characterization of platelet-specific mRNA by real-time PCR after laser-assisted microdissection

Cofilin, a hypoxia-regulated protein in murine lungs identified by 2DE: role of the cytoskeletal protein cofilin in pulmonary hypertension

Compartment-specific expression of collagens and their processing enzymes in intrapulmonary arteries of IPAH patients

Comprehensive analysis of inflammatory markers in chronic thromboembolic pulmonary hypertension patients

Disconnect between Fibrotic Response and Right Ventricular Dysfunction

Distinct differences in gene expression patterns in pulmonary arteries of patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis with pulmonary hypertension.

Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation

Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension

Dysregulated Bone Morphogenetic Protein Signaling in Monocrotaline-Induced Pulmonary Arterial Hypertension

Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.

Echocardiographic Measurement of Right Ventricular Diastolic Parameters in Mouse

Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration

Editorial: Molecular Mechanisms in Pulmonary Hypertension and Right Ventricle Dysfunction

Editorial: Multitasking Biomolecules in Human Pathologies: Known Players on Their Unexpected Journeys

Endothelial Basement Membrane Components and Their Products, Matrikines: Active Drivers of Pulmonary Hypertension?

Endothelial Dysfunction Following Enhanced TMEM16A Activity in Human Pulmonary Arteries

Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.

Expression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertension

FHL-1 is not involved in pressure overload-induced maladaptive right ventricular remodeling and dysfunction

Fhl-1, a new key protein in pulmonary hypertension.

Forschung in Österreich – das Ludwig Boltzmann Institut für Lungengefäßforschung

Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner

Functional and molecular factors associated with TAPSE in hypoxic pulmonary hypertension.

High-mobility group box-1 induces vascular remodelling processes via c-Jun activation

Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure

Hyperoxia modulates TGF-beta/BMP signaling in a mouse model of bronchopulmonary dysplasia

Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.

Hypoxic vascular response and ventilation/perfusion matching in end-stage COPD may depend on p22phox.

IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis

Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration

Identification of proteins in laser-microdissected small cell numbers by SELDI-TOF and Tandem MS

Impact of S-adenosylmethionine decarboxylase 1 on pulmonary vascular remodeling.

Impact of TASK-1 in Human Pulmonary Artery Smooth Muscle Cells

Importance of kynurenine in pulmonary hypertension.

Increased S100A4 expression in the vasculature of human COPD lungs and murine model of smoke-induced emphysema

Inducible NOS Inhibition Reverses Tobacco-Smoke-Induced Emphysema and Pulmonary Hypertension in Mice

Inhibiting eicosanoid degradation exerts antifibrotic effects in a pulmonary fibrosis mouse model and human tissue

Kinases as potential targets for treatment of pulmonary hypertension and right ventricular dysfunction

LRP1 promotes synthetic phenotype of pulmonary artery smooth muscle cells in pulmonary hypertension

Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia

Laser Capture Microdissection of Tissue Sections for High-Throughput RNA Analysis.

Laser-microdissection for cell type- and compartment-specific analyses on genomic and proteomic level

Lessons from Transcriptomics in Hypoxia Induced Pulmonary Hypertension: Does the Mouse Strain Matter?

Long non-coding RNAs influence the transcriptome in pulmonary arterial hypertension: the role of PAXIP1-AS1

Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-β1 from ECM stores

Machine Learning Analysis of the Bleomycin Mouse Model Reveals the Compartmental and Temporal Inflammatory Pulmonary Fingerprint

Meprin β contributes to collagen deposition in lung fibrosis

Meprinβ, a novel mediator of vascular remodelling underlying pulmonary hypertension

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis

Metformin induces lipogenic differentiation in myofibroblasts to reverse mouse and human lung fibrosis

Microarray analysis in pulmonary hypertension

NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension

Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.

No indication of insulin resistance in idiopathic PAH with preserved physical activity

Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction.

Origin of neomuscularized vessels in mice exposed to chronic hypoxia.

PAR-2 inhibition reverses experimental pulmonary hypertension.

PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis

Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018

Peroxisome proliferator-activated receptor-β/δ, the acute signaling factor in prostacyclin-induced pulmonary vasodilation

Perspective: ambient air pollution: inflammatory response and effects on the lung's vasculature

Phosphodiesterase 1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy

Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors

Pressure Overload Creates Right Ventricular Diastolic Dysfunction in a Mouse Model: Assessment by Echocardiography

Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells - potential role in lung fibrosis.

RFLP analysis of 1-aminocyclopropane-1-carboxylate synthase ACC2 and ACC4 genes from Polish cultivars of tomato

Receptor for Activated C-Kinase 1, a Novel Interaction Partner of Type II Bone Morphogenetic Protein Receptor, Regulates Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension

Resident cell lineages are preserved in pulmonary vascular remodeling

Right ventricular fibrosis and dysfunction: Actual concepts and common misconceptions.

Role of protease-activated receptor-2 in idiopathic pulmonary fibrosis.