List of works - Junfei Jin

A comprehensive method for predicting fatal liver failure of patients with liver cancer resection

scientific article

A novel prognostic biomarker SPC24 up-regulated in hepatocellular carcinoma.

scientific article published on 21 October 2015

AKR1B10 Activates Diacylglycerol (DAG) Second Messenger in Breast Cancer Cells.

scientific article

AKR1B10 promotes breast cancer metastasis through integrin α5/δ-catenin mediated FAK/Src/Rac1 signaling pathway.

scientific article published on 27 May 2016

AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells.

scientific article published on 15 June 2009

Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet beta-cells.

scientific article

Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate.

scientific article published on 7 March 2016

Anti-profibrotic effects of artesunate on bleomycin-induced pulmonary fibrosis in Sprague Dawley rats

scientific article published on 17 March 2015

Association between miR-199a rs74723057 and MET rs1621 polymorphisms and the risk of hepatocellular carcinoma.

scientific article

Bcl-2 and Bcl-xL mediate resistance to receptor tyrosine kinase-targeted therapy in lung and gastric cancer.

scientific article published on 6 September 2017

CD8(+) Tregs promote GVHD prevention and overcome the impaired GVL effect mediated by CD4(+) Tregs in mice

scientific article published on 28 March 2016

CaMKII/proteasome/cytosolic calcium/cathepsin B axis was present in tryspin activation induced by nicardipine

scientific article published on 02 July 2019

Cancer, obesity, and diabetes: TKIs exert multiple effects on glucose homeostasis.

scientific article

Caspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress.

scientific article

Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells

scientific article

Coactivation of TLR4 and TLR2/6 coordinates an additive augmentation on IL-6 gene transcription via p38MAPK pathway in U937 mononuclear cells.

scientific article

DEP domain containing 1 suppresses apoptosis via inhibition of A20 expression, which activates the nuclear factor κB signaling pathway in HepG2 cells.

scientific article

Different signaling mechanisms regulating IL-6 expression by LPS between gingival fibroblasts and mononuclear cells: seeking the common target ⬇️

scientific article published on February 10, 2012

Dihydroceramide-desaturase-1-mediated caspase 9 activation through ceramide plays a pivotal role in palmitic acid-induced HepG2 cell apoptosis.

scientific article published in September 2016

Docosahexaenoic acid antagonizes the boosting effect of palmitic acid on LPS inflammatory signaling by inhibiting gene transcription and ceramide synthesis.

scientific article

Elevated preoperative aspartate aminotransferase to lymphocyte ratio index as an independent prognostic factor for patients with hepatocellular carcinoma after hepatic resection

scientific article

GPR40/FFA1 and neutral sphingomyelinase are involved in palmitate-boosted inflammatory response of microvascular endothelial cells to LPS.

scientific article

Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P

scientific article

Golgi fragmentation is associated with ceramide-induced cellular effects.

scientific article

High KIF18A expression correlates with unfavorable prognosis in primary hepatocellular carcinoma

scientific article

High USP22 expression indicates poor prognosis in hepatocellular carcinoma.

scientific article published in May 2015

Inhibition of AMP-activated protein kinase pathway sensitizes human leukemia K562 cells to nontoxic concentration of doxorubicin.

scientific article published on 26 March 2010

Intestinal immunity in hypopituitary dwarf mice: effects of age.

scientific article published on 2 March 2018

LPS and palmitate synergistically stimulate sphingosine kinase 1 and increase sphingosine 1 phosphate in RAW264.7 macrophages.

scientific article

Licorice root extract and magnesium isoglycyrrhizinate protect against triptolide-induced hepatotoxicity via up-regulation of the Nrf2 pathway

scientific article published on 01 November 2018

Low-dose cytokine-induced neutral ceramidase secretion from INS-1 cells via exosomes and its anti-apoptotic effect

scientific article published on 15 May 2014

MD-2 is involved in the stimulation of matrix metalloproteinase-1 expression by interferon-γ and high glucose in mononuclear cells - a potential role of MD-2 in Toll-like receptor 4-independent signalling.

scientific article published in November 2013

MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice.

scientific article

Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.

scientific article

Natural IgM initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration.

scientific article

Neutral ceramidase activity inhibition is involved in palmitate-induced apoptosis in INS-1 cells.

scientific article published in July 2017

Neutral ceramidase-enriched exosomes prevent palmitic acid-induced insulin resistance in H4IIEC3 hepatocytes.

scientific article published on 20 October 2016

Periodontal CD14 mRNA expression is downregulated in patients with chronic periodontitis and type 2 diabetes

scientific article published on 18 November 2015

Preoperative Aspartate Aminotransferase to White Blood Cell Count Ratio Predicting Postoperative Outcomes of Hepatocellular Carcinoma.

scientific article published on April 2016

Preoperative Neutrophil-to-Lymphocyte Ratio as a New Prognostic Marker in Hepatocellular Carcinoma after Curative Resection.

scientific article

Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells

scientific article published on 9 October 2017

Role of aldo-keto reductases in development of prostate and breast cancer.

scientific article

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.

scientific article

Simvastatin inhibits lipopolysaccharide-induced osteoclastogenesis and reduces alveolar bone loss in experimental periodontal disease

scientific article published on 07 October 2013

Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)

scientific article

T-bet Promotes Acute Graft-versus-Host Disease by Regulating Recipient Hematopoietic Cells in Mice.

scientific article published on 22 February 2016

TLR4 activation and IL-6-mediated cross talk between adipocytes and mononuclear cells synergistically stimulate MMP-1 expression.

scientific article published on 27 September 2011

TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice.

scientific article

Targeted interfering DEP domain containing 1 protein induces apoptosis in A549 lung adenocarcinoma cells through the NF-κB signaling pathway

scientific article published on 11 September 2017

The complement system is also important in immunogenic cell death

scientific article published on 28 December 2016

The role of acid sphingomyelinase and caspase 5 in hypoxia-induced HuR cleavage and subsequent apoptosis in hepatocytes.

scientific article published on 11 August 2012

Toll-like receptor 4 activation in microvascular endothelial cells triggers a robust inflammatory response and cross talk with mononuclear cells via interleukin-6.

scientific article published on 17 May 2012

Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1

scientific article published on 10 May 2018

Upregulation of RECQL4 expression predicts poor prognosis in hepatocellular carcinoma.

scientific article published on 25 January 2018

Upregulation of hyaluronan-mediated motility receptor in hepatocellular carcinoma predicts poor survival.

scientific article

[The model's establishment of the single cell (HepG2) clones over expressed ARL-1 gene]

scientific article published on 01 December 2002

p38 mitogen-activated protein kinase/activator protein-1 involved in serum deprivation-induced human alkaline ceramidase 2 upregulation

scientific article

List of works by Junfei Jin

A comprehensive method for predicting fatal liver failure of patients with liver cancer resection

A novel prognostic biomarker SPC24 up-regulated in hepatocellular carcinoma.

AKR1B10 Activates Diacylglycerol (DAG) Second Messenger in Breast Cancer Cells.

AKR1B10 promotes breast cancer metastasis through integrin α5/δ-catenin mediated FAK/Src/Rac1 signaling pathway.

AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells.

Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet beta-cells.

Aldo-keto Reductase Family 1 Member B 10 Mediates Liver Cancer Cell Proliferation through Sphingosine-1-Phosphate.

Anti-profibrotic effects of artesunate on bleomycin-induced pulmonary fibrosis in Sprague Dawley rats

Association between miR-199a rs74723057 and MET rs1621 polymorphisms and the risk of hepatocellular carcinoma.

Bcl-2 and Bcl-xL mediate resistance to receptor tyrosine kinase-targeted therapy in lung and gastric cancer.

CD8(+) Tregs promote GVHD prevention and overcome the impaired GVL effect mediated by CD4(+) Tregs in mice

CaMKII/proteasome/cytosolic calcium/cathepsin B axis was present in tryspin activation induced by nicardipine

Cancer, obesity, and diabetes: TKIs exert multiple effects on glucose homeostasis.

Caspase-mediated cleavage of RNA-binding protein HuR regulates c-Myc protein expression after hypoxic stress.

Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells

Coactivation of TLR4 and TLR2/6 coordinates an additive augmentation on IL-6 gene transcription via p38MAPK pathway in U937 mononuclear cells.

DEP domain containing 1 suppresses apoptosis via inhibition of A20 expression, which activates the nuclear factor κB signaling pathway in HepG2 cells.

Different signaling mechanisms regulating IL-6 expression by LPS between gingival fibroblasts and mononuclear cells: seeking the common target ⬇️

Dihydroceramide-desaturase-1-mediated caspase 9 activation through ceramide plays a pivotal role in palmitic acid-induced HepG2 cell apoptosis.

Docosahexaenoic acid antagonizes the boosting effect of palmitic acid on LPS inflammatory signaling by inhibiting gene transcription and ceramide synthesis.

Elevated preoperative aspartate aminotransferase to lymphocyte ratio index as an independent prognostic factor for patients with hepatocellular carcinoma after hepatic resection

GPR40/FFA1 and neutral sphingomyelinase are involved in palmitate-boosted inflammatory response of microvascular endothelial cells to LPS.

Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P

Golgi fragmentation is associated with ceramide-induced cellular effects.

High KIF18A expression correlates with unfavorable prognosis in primary hepatocellular carcinoma

High USP22 expression indicates poor prognosis in hepatocellular carcinoma.

Inhibition of AMP-activated protein kinase pathway sensitizes human leukemia K562 cells to nontoxic concentration of doxorubicin.

Intestinal immunity in hypopituitary dwarf mice: effects of age.

LPS and palmitate synergistically stimulate sphingosine kinase 1 and increase sphingosine 1 phosphate in RAW264.7 macrophages.

Licorice root extract and magnesium isoglycyrrhizinate protect against triptolide-induced hepatotoxicity via up-regulation of the Nrf2 pathway

Low-dose cytokine-induced neutral ceramidase secretion from INS-1 cells via exosomes and its anti-apoptotic effect

MD-2 is involved in the stimulation of matrix metalloproteinase-1 expression by interferon-γ and high glucose in mononuclear cells - a potential role of MD-2 in Toll-like receptor 4-independent signalling.

MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice.

Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.

Natural IgM initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration.

Neutral ceramidase activity inhibition is involved in palmitate-induced apoptosis in INS-1 cells.

Neutral ceramidase-enriched exosomes prevent palmitic acid-induced insulin resistance in H4IIEC3 hepatocytes.

Periodontal CD14 mRNA expression is downregulated in patients with chronic periodontitis and type 2 diabetes

Preoperative Aspartate Aminotransferase to White Blood Cell Count Ratio Predicting Postoperative Outcomes of Hepatocellular Carcinoma.

Preoperative Neutrophil-to-Lymphocyte Ratio as a New Prognostic Marker in Hepatocellular Carcinoma after Curative Resection.

Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells

Role of aldo-keto reductases in development of prostate and breast cancer.

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.

Simvastatin inhibits lipopolysaccharide-induced osteoclastogenesis and reduces alveolar bone loss in experimental periodontal disease

Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)

T-bet Promotes Acute Graft-versus-Host Disease by Regulating Recipient Hematopoietic Cells in Mice.

TLR4 activation and IL-6-mediated cross talk between adipocytes and mononuclear cells synergistically stimulate MMP-1 expression.

TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice.

Targeted interfering DEP domain containing 1 protein induces apoptosis in A549 lung adenocarcinoma cells through the NF-κB signaling pathway

The complement system is also important in immunogenic cell death

The role of acid sphingomyelinase and caspase 5 in hypoxia-induced HuR cleavage and subsequent apoptosis in hepatocytes.

Toll-like receptor 4 activation in microvascular endothelial cells triggers a robust inflammatory response and cross talk with mononuclear cells via interleukin-6.

Trabid inhibits hepatocellular carcinoma growth and metastasis by cleaving RNF8-induced K63 ubiquitination of Twist1

Upregulation of RECQL4 expression predicts poor prognosis in hepatocellular carcinoma.

Upregulation of hyaluronan-mediated motility receptor in hepatocellular carcinoma predicts poor survival.

[The model's establishment of the single cell (HepG2) clones over expressed ARL-1 gene]

p38 mitogen-activated protein kinase/activator protein-1 involved in serum deprivation-induced human alkaline ceramidase 2 upregulation