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List of works by Moreno Paolini

A database for evaluating the toxicological risk of pesticides.

scientific article published on January 1997

A hidden paradox in carcinogenesis bioassays

scientific article published on 01 May 1997

A linearization method for low catalytic activity enzyme kinetic analysis.

scientific article published on 5 January 2005

A unified theory of enzyme kinetics based upon the systematic analysis of the variations of k(cat), K(M), and k(cat)/K(M) and the relevant DeltaG(0 not equal) values-possible implications in chemotherapy and biotechnology.

scientific article

Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice.

scientific article

Animal rights activists: misconceived proposals

scientific article published on 31 December 2014

Anti-diabetic properties of a non-conventional radical scavenger, as compared to pioglitazone and exendin-4, in streptozotocin-nicotinamide diabetic mice

scientific article published on 12 February 2014

Antioxidant vitamins for prevention of cardiovascular disease

scientific article published in The Lancet

Avoidance of bioflavonoid supplements during pregnancy: a pathway to infant leukemia?

scientific article (publication date: 19 June 2003)

Beneficial effect of the nonpeptidyl low molecular weight radical scavenger IAC on cultured human islet function.

scientific article published in January 2008

Beta-carotene: a cancer chemopreventive agent or a co-carcinogen?

scientific article

Bile acid structure and selective modulation of murine hepatic cytochrome P450-linked enzymes

scientific article published on 01 September 1999

Biomarkers of effect in evaluating dithianon cocarcinogenesis: selective induction and suppression of murine CYP3A isoform.

scientific article published in February 1997

Black cabbage seed extract affects rat Cyp-mediated biotransformation: organ and sex related differences

scientific article published on 23 May 2012

Brussels sprouts: an exceptionally rich source of ambiguity for anticancer strategies

scientific article published on 01 October 1998

Cancer chemoprevention from the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine: reconsideration of the evidence

scientific article published on 01 November 1997

Cancer chemoprevention: some complications and limitations

scientific article published on 01 January 1998

Chemoprevention or antichemoprevention? A salutary warning From the beta-carotene experience.

scientific article published in July 2001

Co-carcinogenic effect of beta-carotene.

scientific article published on April 1999

Cocktail strategy: complications and limitations

scientific article published on 01 November 1993

Commentary--measurement of microsomal epoxide hydrolase activity in humans: problems and perspectives

scientific article published on January 1, 1997

Comparative genetic activity of cis- and trans-1,2-dichloroethylene in yeast

scientific article published on 01 January 1984

Comparison between chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effects on rat liver CYP-catalysed drug metabolism

article

Comparisons between in vivo and in vitro systems: the in vivo equivalent dose concept

scientific article published on 01 November 1988

Cruciferous vegetables and lung cancer

article

Cyclosporin A and free radical generation.

scientific article published in January 2001

Cytochrome P-450 factors determining synthesis in strain D7 Saccharomyces cerevisiae. An alternative system to microsomal assay

scientific article published on 01 August 1983

Cytotoxic activity and transformation of BALB/c 3T3 cells in vitro by the insecticide acephate.

scientific article published on September 1996

Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.

scientific article published on 12 January 2008

Cytotoxic and cell transforming activities of the fungicide methyl thiophanate on BALB/c 3T3 cells in vitro.

scientific article

Defining "enzyme unit" correctly

scientific article published on 01 July 1996

Detection of genotoxicants in the leather and tannery industry using short-term tests

scientific article published on 01 February 1983

Detection of mutagens in leather and tannery industry assay of 28 commercial mixtures.

scientific article published in April 1984

Development of basal and induced testosterone hydroxylase activity in the chicken embryo in ovo

scientific article

Diet and risk of cancer

article by Moreno Paolini et al published 1 January 2003 in The Lancet

Dietary effect on blood pressure

Dimethylsulfoxide as modifier of the organospecific mutagenicity of metronidazole in mice

scientific article published on 01 January 1990

Direct antioxidant activity of purified glucoerucin, the dietary secondary metabolite contained in rocket (Eruca sativa Mill.) seeds and sprouts

scientific article published in April 2005

Direction selectivity in the middle lateral and lateral (ML and L) visual areas in the California ground squirrel.

scientific article

Do cytochromes P-448 and P-450 have different functions?

scientific article

EDTA affects cytochrome P450-dependent biotransformation reactions during incubations for the liver microsomal assay

scientific article published on 01 July 1988

Effect of licorice and glycyrrhizin on murine liver CYP-dependent monooxygenases

scientific article published on 01 January 1998

Effect of repeated ether anesthesias on levels and stability of monooxygenase system activities of mouse liver.

scientific article published in September 1982

Effect of repeated ether anesthesias on the mono-oxygenase system of mouse-liver S9 fraction.

scientific article published in January 1983

Effect of repeated ether anesthesias on the mono-oxygenase system of rat liver S-9 fraction.

scientific article published in January 1984

Effect of sprout extract from Tuscan black cabbage on xenobiotic-metabolizing and antioxidant enzymes in rat liver

scientific article published on 24 November 2012

Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer

scientific article published on 01 January 2003

Effects of N-acetylcysteine on human ovarian tissue preservation undergoing cryopreservation procedure

scientific article published on 26 December 2014

Effects of metronidazole, azanidazole, and azathioprine on cytochrome P450 and various mono-oxygenase activities in hepatic microsomes from control and induced mice

scientific article published on 01 January 1987

Effects of the non-peptidyl low molecular weight radical scavenger IAC in DNBS-induced colitis in rats

scientific article published on 19 April 2009

Effects of trivalent chromium on hepatic CYP-linked monooxygenases in laying hens.

scientific article

Enzyme evolution and cancer: hypothesis why natural carcinogens are more potent than synthetic ones

scientific article published on 01 January 1998

Erythrocytes-mediated metabolic activation of cyclophosphamide in yeast mutagenicity test.

scientific article published in January 1985

Expressing the specificity and the potency of cytochrome P-450 inducers toward 7-ethoxyresorufin

scientific article published on 01 September 1990

Further mechanisms of non-genotoxic carcinogenesis.

scientific article published in September 1994

Genetic and biochemical effects of dry residue of Arno river in vitro and in vivo

scientific article published on 01 May 1987

Genetic and biochemical investigation on chloral hydrate in vitro and in vivo

scientific article published on 01 September 1984

Genetic and biochemical studies on perchloroethylene 'in vitro' and 'in vivo'

scientific article published on 01 March 1983

Genetic and non-genetic biomarkers related to carcinogenesis in evaluating toxicological risk from Fenarimol

scientific article published on 01 May 1996

Genotoxic and biochemical effects of dimethylamine

scientific article published on 01 May 1993

Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver

scientific article

Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats

article published in 2007

Glutathione transferase polymorphism and Parkinson's disease

scientific article published on 01 January 1999

Healthy broccoli?

scientific article published in Nature

Hidden paradoxes in generic drug substitution affecting pharmacotherapy.

scientific article published on 21 May 2009

High-dose vitamin A

scientific article published on 01 September 2007

How to avoid calculations during treatment of numerous groups of laboratory animals with a single appropriate dose in mg/Kg b.w.: an original technical note.

scientific article published in January 1994

Hydroxyl radical generation, levels of tumor necrosis factor-alpha, and progression to heart failure after acute myocardial infarction

scientific article (publication date: 2 June 2004)

Improvement of short-term tests for mutagenicity: on the optimal pH for the liver microsomal assay

scientific article published on 01 December 1988

In vitro and in silico processes to identify differentially expressed proteins

scientific article published on 01 August 2004

In vitro induction of benzo(a)pyrene cell-transforming activity by the glucosinolate gluconasturtiin found in cruciferous vegetables

scientific article published on October 2002

In vivo protective role of antioxidants against genotoxicity of metronidazole and azanidazole

scientific article published on 01 January 1987

Inducibility of NADPH cytochrome c (P-450) reductase in yeast: role in the bioactivation of nitroimidazo(2,1-b)thiazoles.

scientific article published in November 1987

Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice

scientific article

Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers ⬇️

scientific article published on March 30, 1995

Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats.

scientific article

Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli

scientific article published on 26 September 2003

Inhibitory activity of vitamin E and alpha-naphthoflavone on beta-carotene-enhanced transformation of BALB/c 3T3 cells by benzo(a)pyrene and cigarette-smoke condensate.

scientific article published on February 2000

Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger

article

Is clonal adaptation a product of evolution over the millennia?

scientific article published in July 1991

Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus sprouts (kaiware daikon) and its redox properties.

scientific article published in December 2005

Isolation of S9 fractions from mouse and rat with increased enzyme activities after repeated administration of cytochrome P-450 and P-448 inducers

scientific article published on 01 May 1988

Isolation of a novel metabolizing system enriched in phase-II enzymes for short-term genotoxicity bioassays.

scientific article published in March 1998

Lack of correlation between free erythrocyte porphyrin and serum ferritin values at birth and at 2 months of life in low birthweight infants.

scientific article

Long-term dietary administration of valproic acid does not affect, while retinoic acid decreases, the lifespan of G93A mice, a model for amyotrophic lateral sclerosis

scientific article

Mechanism for the prevention of cholestasis involving cytochrome P4503A overexpression

scientific article published on 01 January 2000

Mechanism of clastogenic and co-clastogenic activity of cremophore with benzene in mice.

scientific article

Metabolizing systems for in vitro genotoxicity tests

scientific article published on 01 May 1996

Methylglyoxal: genotoxicity studies and its effect in vivo on the hepatic microsomal mono-oxygenase system of the mouse.

scientific article published in July 1987

Modulation of cytochrome P450 and induction of DNA damage in Cyprinus carpio exposed in situ to surface water treated with chlorine or alternative disinfectants in different seasons.

scientific article published on 4 October 2011

Molecular non-genetic biomarkers of effect related to acephate cocarcinogenesis: sex- and tissue-dependent induction or suppression of murine CYPs ⬇️

scientific article published on July 15, 1997

Molecular non-genetic biomarkers related to Fenarimol cocarcinogenesis: organ- and sex-specific CYP induction in rat.

scientific article published in March 1996

Murine alpha/beta interferons inhibit benzo(a)pyrene activation and mutagenesis in mice

scientific article published on 01 January 1993

Mutagenicity of styrene on metabolizing D7 strain of saccharomyces cerevisiae

scientific article published on 01 January 1983

NADPH as rate-limiting factor for microsomal metabolism. An alternative and economic NADPH-generating system for microsomal mono-oxygenase in in vitro genotoxicity studies.

scientific article published on May 1987

NADPH-generating system: influence on microsomal mono-oxygenase stability during incubation for the liver-microsomal assay with rat and mouse S9 fractions.

scientific article published on December 1984

NEONATAL SCREENING FOR CONGENITAL ADRENAL HYPERPLASIA

scientific article published in The Lancet

Neonatal screening for 21-hydroxylase deficiency: a microfilter paper method for 17-α-hydroxyprogesterone assay

article

Non-peptidyl low molecular weight radical scavenger IAC attenuates DSS-induced colitis in rats

scientific article published on August 2010

On cancer chemoprevention: complications and limitations of some proposed strategies

scientific article published on 01 April 1995

On enzyme-based anticancer molecular dietary manipulations

scientific article published on 20 September 2012

On the hepatotoxicity of 1,1,2,2-tetrachloroethane

scientific article published on 01 January 1992

On the metabolizing systems for short-term genotoxicity assays: a review.

scientific article published on August 1997

On the nature of non-genotoxic carcinogens. A unified theory including NGCs, co-carcinogens and promoters

scientific article published on April 1, 1992

On the procedures for isolation of S9 fractions from induced rodents in in vitro genotoxicity assays

scientific article published on 01 January 1994

On the usefulness of drug metabolising enzyme modulation for anti-cancer strategies

scientific article published on 01 August 1998

Oxidative stress and aging: a non-invasive EPR investigation in human volunteers

scientific article published on 31 July 2014

Paramagnetic resonance in detecting carcinogenic risk from cytochrome P450 overexpression.

scientific article

Parkinson's disease, pesticides and individual vulnerability

scientific article published on March 2004

Perturbation of cytochrome P450, generation of oxidative stress and induction of DNA damage in Cyprinus carpio exposed in situ to potable surface water

scientific article published in December 2006

Perturbation of rat hepatic metabolising enzymes by folic acid supplementation

scientific article published on 28 June 2007

Perturbation of xenobiotic metabolism in Dreissena polymorpha model exposed in situ to surface water (Lake Trasimene) purified with various disinfectants

scientific article published on 18 September 2015

Pharmacokinetics of ursodeoxycholic acid in rat

scientific article published on 01 May 1991

Pitfalls of enzyme-based molecular anticancer dietary manipulations: food for thought

scientific article

Plasma ascorbic acid in heart disease.

scientific article published in July 2001

Polymorphism in gene for microsomal epoxide hydrolase and lung disease

scientific article published on 01 November 1997

Problems connected with neonatal screening assays

scientific article published on 01 October 1982

Protective effect of Tuscan black cabbage sprout extract against serum lipid increase and perturbations of liver antioxidant and detoxifying enzymes in rats fed a high-fat diet.

scientific article published on 25 February 2013

Quantitative evaluation of oxidative stress status on peripheral blood in beta-thalassaemic patients by means of electron paramagnetic resonance spectroscopy.

scientific article published in October 2005

Re: Barcelo, S., Gardiner, J.M., and Gescher, A. and Chipman, J.K. (1996) CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane. Carcinogenesis, 17, 277-282.

scientific article published in July 1997

Re: dioxin increases reactive oxygen production in mouse liver mitochondria (toxicol. Appl. Pharmacol.178, 15-21, 2002). To the editor.

scientific article published in November 2002

Redox-Based Flagging of the Global Network of Oxidative Stress Greatly Promotes Longevity

scientific article

Role of proteases on monooxygenase system inactivation in incubation mixtures for the "in vitro" mutagenesis test with metabolic activation. Studies on proteolytic activity at different temperatures

scientific article published on 01 October 1982

Short-chain aliphatic halocompounds: "in vivo" effects on microsomal monooxygenase (P450-dependent) system

scientific article published on February 1, 1992

Single nucleotide polymorphisms of the DNA repair gene XPD/ERCC2 alter mRNA expression

scientific article published on 01 November 2007

Stability of drug metabolizing enzymes during the incubation conditions of the liver microsomal assay with non-induced and induced mouse liver S-9 fractions.

scientific article published on September 1987

Stability of microsomal mono-oxygenase during incubations for the liver microsomal assay with S9 fractions of mouse liver under various inductions.

scientific article

Stability of microsomal monooxygenases in murine liver S9 fractions derived from phenobarbital and beta-naphthoflavone induced animals under various long-term conditions of storage

scientific article published on 01 January 1994

Strategies for advancement of short-term mutagenicity tests: on the optimal ionic strength for the liver microsomal assay

scientific article published on August 1, 1992

Strategies for optimization of short-term genotoxicity tests: the synergistic effect of NADPH and NADH on P450 function in processing pre mutagens

scientific article published on 01 January 1990

Studies of genetic effects in the D7 strain of Saccharomyces cerevisiae under different conditions of pH

scientific article published on 01 April 1984

Studies on microsomal metabolizing systems for mutagenesis tests. Stability of fortified fractions

scientific article published on 01 September 1981

Study of the optimal temperature for the liver microsomal assay with mice S9 fractions

scientific article published on 01 October 1985

Taking EPR "snapshots" of the oxidative stress status in human blood

scientific article

Testosterone hydroxylase in evaluating induction and suppression of murine CYP isoenzymes by fenarimol.

scientific article published in January 1996

Tetrachloroethane, pentachloroethane, and hexachloroethane: genetic and biochemical studies.

scientific article

The efficient preparation of corn oil solutions

scientific article published on 01 September 1988

The genetic and non-genetic toxicity of the fungicide Vinclozolin.

scientific article published on September 1996

The metalloporphyrin/oxidant model for cytochrome P450

scientific article published on 01 July 1997

The modulating activity of interferon on benzo(a)pyrene bioactivation and clastogenesis in mice.

scientific article

The novel radical scavenger IAC is effective in preventing and protecting against post-ischemic brain damage in Mongolian gerbils

scientific article published on 28 November 2009

The organospecific activity of metronidazole and azanidazole in the intrasanguineous host-mediated assay.

scientific article

The pitfall of detoxifying enzymes

scientific article published on 01 June 1998

The pressing need for combined genotype-phenotype analysis in clinical practice

scientific article published on 01 June 2002

The sympathy of policy-makers towards animal-rights activists, and the future of biomedical research

scientific article published on 10 July 2014

The synergistic effect of NADPH and NADH on P450 function in processing premutagens

scientific article published on 01 November 1989

Ursodeoxycholic acid (UDCA) prevents DCA effects on male mouse liver via up-regulation of CYP [correction of CXP] and preservation of BSEP activities

scientific article published in August 2002

[Black widow bites. 3 cases]

scientific article published on 01 January 1997

[Critical aspects in determining total radioactivity of biological samples]

scientific article published on 01 March 1989

[Genetic activity of 1,2-dichloroethylene. A). In vitro studies]

scientific article published on 01 July 1982

[Genetic activity of 1,2-dichloroethylene. B). In vivo studies: effect on microsomal enzymes]

scientific article published on 01 July 1982

[Levels of xenobiotic metabolizing enzyme activities of xenobiotic tissue in different animal species]

scientific article published on 01 September 1982

beta-carotene as enhancer of cell transforming activity of powerful carcinogens and cigarette-smoke condensate on BALB/c 3T3 cells in vitro.

scientific article published on March 1999

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