List of works - Moreno Paolini

Co-carcinogenic effect of beta-carotene.

scientific article published on April 1999

Beta-carotene: a cancer chemopreventive agent or a co-carcinogen?

scientific article

Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.

scientific article published on 12 January 2008

Comparison between chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effects on rat liver CYP-catalysed drug metabolism

article

Direct antioxidant activity of purified glucoerucin, the dietary secondary metabolite contained in rocket (Eruca sativa Mill.) seeds and sprouts

scientific article published in April 2005

Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats.

scientific article

Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus sprouts (kaiware daikon) and its redox properties.

scientific article published in December 2005

Long-term dietary administration of valproic acid does not affect, while retinoic acid decreases, the lifespan of G93A mice, a model for amyotrophic lateral sclerosis

scientific article

Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer

scientific article published on 01 January 2003

Direction selectivity in the middle lateral and lateral (ML and L) visual areas in the California ground squirrel.

scientific article

Single nucleotide polymorphisms of the DNA repair gene XPD/ERCC2 alter mRNA expression

scientific article published on 01 November 2007

Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver

scientific article

Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli

scientific article published on 26 September 2003

Hydroxyl radical generation, levels of tumor necrosis factor-alpha, and progression to heart failure after acute myocardial infarction

scientific article (publication date: 2 June 2004)

Effect of licorice and glycyrrhizin on murine liver CYP-dependent monooxygenases

scientific article published on 01 January 1998

In vitro and in silico processes to identify differentially expressed proteins

scientific article published on 01 August 2004

Ursodeoxycholic acid (UDCA) prevents DCA effects on male mouse liver via up-regulation of CYP [correction of CXP] and preservation of BSEP activities

scientific article published in August 2002

beta-carotene as enhancer of cell transforming activity of powerful carcinogens and cigarette-smoke condensate on BALB/c 3T3 cells in vitro.

scientific article published on March 1999

Further mechanisms of non-genotoxic carcinogenesis.

scientific article published in September 1994

Parkinson's disease, pesticides and individual vulnerability

scientific article published on March 2004

Bile acid structure and selective modulation of murine hepatic cytochrome P450-linked enzymes

scientific article published on 01 September 1999

Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger

article

Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers

scientific article published on March 30, 1995

Protective effect of Tuscan black cabbage sprout extract against serum lipid increase and perturbations of liver antioxidant and detoxifying enzymes in rats fed a high-fat diet.

scientific article published on 25 February 2013

Stability of microsomal monooxygenases in murine liver S9 fractions derived from phenobarbital and beta-naphthoflavone induced animals under various long-term conditions of storage

scientific article published on 01 January 1994

Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice

scientific article

Molecular non-genetic biomarkers related to Fenarimol cocarcinogenesis: organ- and sex-specific CYP induction in rat.

scientific article published in March 1996

Perturbation of cytochrome P450, generation of oxidative stress and induction of DNA damage in Cyprinus carpio exposed in situ to potable surface water

scientific article published in December 2006

Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice.

scientific article

Healthy broccoli?

scientific article published in Nature

On the metabolizing systems for short-term genotoxicity assays: a review.

scientific article published on August 1997

The genetic and non-genetic toxicity of the fungicide Vinclozolin.

scientific article published on September 1996

A unified theory of enzyme kinetics based upon the systematic analysis of the variations of k(cat), K(M), and k(cat)/K(M) and the relevant DeltaG(0 not equal) values-possible implications in chemotherapy and biotechnology.

scientific article

Chemoprevention or antichemoprevention? A salutary warning From the beta-carotene experience.

scientific article published in July 2001

On the nature of non-genotoxic carcinogens. A unified theory including NGCs, co-carcinogens and promoters

scientific article published on April 1, 1992

Testosterone hydroxylase in evaluating induction and suppression of murine CYP isoenzymes by fenarimol.

scientific article published in January 1996

Molecular non-genetic biomarkers of effect related to acephate cocarcinogenesis: sex- and tissue-dependent induction or suppression of murine CYPs

scientific article published on July 15, 1997

Cocktail strategy: complications and limitations

scientific article published on 01 November 1993

Is clonal adaptation a product of evolution over the millennia?

scientific article published in July 1991

Redox-Based Flagging of the Global Network of Oxidative Stress Greatly Promotes Longevity

scientific article

Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats

article published in 2007

Taking EPR "snapshots" of the oxidative stress status in human blood

scientific article

The modulating activity of interferon on benzo(a)pyrene bioactivation and clastogenesis in mice.

scientific article

Methylglyoxal: genotoxicity studies and its effect in vivo on the hepatic microsomal mono-oxygenase system of the mouse.

scientific article published in July 1987

Isolation of a novel metabolizing system enriched in phase-II enzymes for short-term genotoxicity bioassays.

scientific article published in March 1998

Do cytochromes P-448 and P-450 have different functions?

scientific article

Diet and risk of cancer

article by Moreno Paolini et al published 1 January 2003 in The Lancet

Paramagnetic resonance in detecting carcinogenic risk from cytochrome P450 overexpression.

scientific article

Mechanism of clastogenic and co-clastogenic activity of cremophore with benzene in mice.

scientific article

The novel radical scavenger IAC is effective in preventing and protecting against post-ischemic brain damage in Mongolian gerbils

scientific article published on 28 November 2009

List of works by Moreno Paolini

Co-carcinogenic effect of beta-carotene.

Beta-carotene: a cancer chemopreventive agent or a co-carcinogen?

Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.

Comparison between chinese medical herb Pueraria lobata crude extract and its main isoflavone puerarin antioxidant properties and effects on rat liver CYP-catalysed drug metabolism

Direct antioxidant activity of purified glucoerucin, the dietary secondary metabolite contained in rocket (Eruca sativa Mill.) seeds and sprouts

Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats.

Isolation of 4-methylthio-3-butenyl glucosinolate from Raphanus sativus sprouts (kaiware daikon) and its redox properties.

Long-term dietary administration of valproic acid does not affect, while retinoic acid decreases, the lifespan of G93A mice, a model for amyotrophic lateral sclerosis

Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer

Direction selectivity in the middle lateral and lateral (ML and L) visual areas in the California ground squirrel.

Single nucleotide polymorphisms of the DNA repair gene XPD/ERCC2 alter mRNA expression

Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver

Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli

Hydroxyl radical generation, levels of tumor necrosis factor-alpha, and progression to heart failure after acute myocardial infarction

Effect of licorice and glycyrrhizin on murine liver CYP-dependent monooxygenases

In vitro and in silico processes to identify differentially expressed proteins

Ursodeoxycholic acid (UDCA) prevents DCA effects on male mouse liver via up-regulation of CYP [correction of CXP] and preservation of BSEP activities

beta-carotene as enhancer of cell transforming activity of powerful carcinogens and cigarette-smoke condensate on BALB/c 3T3 cells in vitro.

Further mechanisms of non-genotoxic carcinogenesis.

Parkinson's disease, pesticides and individual vulnerability

Bile acid structure and selective modulation of murine hepatic cytochrome P450-linked enzymes

Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger

Induction of CYP2B1 mediated pentoxyresorufin O-dealkylase activity in different species, sex and tissue by prototype 2B1-inducers

Protective effect of Tuscan black cabbage sprout extract against serum lipid increase and perturbations of liver antioxidant and detoxifying enzymes in rats fed a high-fat diet.

Stability of microsomal monooxygenases in murine liver S9 fractions derived from phenobarbital and beta-naphthoflavone induced animals under various long-term conditions of storage

Induction and suppression of cytochrome P450 isoenzymes and generation of oxygen radicals by procymidone in liver, kidney and lung of CD1 mice

Molecular non-genetic biomarkers related to Fenarimol cocarcinogenesis: organ- and sex-specific CYP induction in rat.

Perturbation of cytochrome P450, generation of oxidative stress and induction of DNA damage in Cyprinus carpio exposed in situ to potable surface water

Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice.

Healthy broccoli?

On the metabolizing systems for short-term genotoxicity assays: a review.

The genetic and non-genetic toxicity of the fungicide Vinclozolin.

A unified theory of enzyme kinetics based upon the systematic analysis of the variations of k(cat), K(M), and k(cat)/K(M) and the relevant DeltaG(0 not equal) values-possible implications in chemotherapy and biotechnology.

Chemoprevention or antichemoprevention? A salutary warning From the beta-carotene experience.

On the nature of non-genotoxic carcinogens. A unified theory including NGCs, co-carcinogens and promoters

Testosterone hydroxylase in evaluating induction and suppression of murine CYP isoenzymes by fenarimol.

Molecular non-genetic biomarkers of effect related to acephate cocarcinogenesis: sex- and tissue-dependent induction or suppression of murine CYPs

Cocktail strategy: complications and limitations

Is clonal adaptation a product of evolution over the millennia?

Redox-Based Flagging of the Global Network of Oxidative Stress Greatly Promotes Longevity

Glucoraphasatin and glucoraphenin, a redox pair of glucosinolates of brassicaceae, differently affect metabolizing enzymes in rats

Taking EPR "snapshots" of the oxidative stress status in human blood

The modulating activity of interferon on benzo(a)pyrene bioactivation and clastogenesis in mice.

Methylglyoxal: genotoxicity studies and its effect in vivo on the hepatic microsomal mono-oxygenase system of the mouse.

Isolation of a novel metabolizing system enriched in phase-II enzymes for short-term genotoxicity bioassays.

Do cytochromes P-448 and P-450 have different functions?

Diet and risk of cancer

Paramagnetic resonance in detecting carcinogenic risk from cytochrome P450 overexpression.

Mechanism of clastogenic and co-clastogenic activity of cremophore with benzene in mice.

The novel radical scavenger IAC is effective in preventing and protecting against post-ischemic brain damage in Mongolian gerbils