List of works - Leonardo Sacconi

A Software Architecture to Mimic a Ventricular Tachycardia in Intact Murine Hearts by Means of an All-Optical Platform

scientific article published on 08 January 2019

A versatile clearing agent for multi-modal brain imaging

scientific article published on 7 May 2015

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

scientific article

Analysis of kinetics in noisy systems: application to single molecule tethered particle motion.

scientific article

Cardiac sympathetic innervation network shapes the myocardium by locally controlling cardiomyocyte size through the cellular proteolytic machinery

scientific article published on 17 June 2019

Cell imaging and manipulation by nonlinear optical microscopy.

scientific article published on January 2006

Clearing of fixed tissue: a review from a microscopist's perspective.

scientific article published on August 2016

Comprehensive optical and data management infrastructure for high-throughput light-sheet microscopy of whole mouse brains

scientific article

Computer-based automatic identification of neurons in gigavoxel-sized 3D human brain images

scientific article published in August 2015

Confocal light sheet microscopy: micron-scale neuroanatomy of the entire mouse brain ⬇️

scientific article published on August 27, 2012

Confocal multispot microscope for fast and deep imaging in semicleared tissues

scientific article published in February 2018

Correcting spherical aberrations in confocal light sheet microscopy: a theoretical study.

scientific article

Correlative two-photon and light sheet microscopy.

scientific article published on 24 June 2013

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure

scientific article

Electrical defects of the transverse-axial tubular system in cardiac diseases

scientific article

Exploring molecular motors and switches at the single-molecule level.

scientific article

Functional cardiac imaging by random access microscopy

scientific article

Impact of detubulation on force and kinetics of cardiac muscle contraction.

scientific article

In vivo multiphoton nanosurgery on cortical neurons.

scientific article published in September 2007

In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex.

scientific article

Label-free near-infrared reflectance microscopy as a complimentary tool for two-photon fluorescence brain imaging

scientific article published on 21 October 2015

Laser nanosurgery of cerebellar axons in vivo

scientific article

Letter to the Editor

scientific article published on 14 April 2019

Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair

scientific article published on 17 October 2017

Micron-scale resolution optical tomography of entire mouse brains with confocal light sheet microscopy

scientific article published on 08 October 2013

Multi-Modal Optical Imaging of the Cerebellum in Animals

scientific article published on 17 October 2015

Multi-photon nanosurgery in live brain.

scientific article

Multiphoton multifocal microscopy exploiting a diffractive optical element

scientific article published on 01 October 2003

New techniques in linear and non-linear laser optics in muscle research.

scientific article

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

scientific article published on 20 December 2015

Nuclear and division-plane positioning revealed by optical micromanipulation

scientific article published on 01 July 2005

Optical micromanipulations inside yeast cells.

scientific article

Optical recording of fast neuronal membrane potential transients in acute mammalian brain slices by second-harmonic generation microscopy.

scientific article

Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation.

scientific article

Optogenetics gets to the heart: A guiding light beyond defibrillation

scientific article published on 12 May 2017

Overcoming photodamage in second-harmonic generation microscopy: real-time optical recording of neuronal action potentials.

scientific article published on 17 February 2006

Palette of fluorinated voltage-sensitive hemicyanine dyes

scientific article

Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.

scientific article published on 22 July 2017

Positioning and elongation of the fission yeast spindle by microtubule-based pushing.

scientific article

Probing myosin structural conformation in vivo by second-harmonic generation microscopy.

scientific article

Protein conformation and molecular order probed by second-harmonic-generation microscopy.

scientific article published on June 2012

Publisher Correction: Whole-Brain Vasculature Reconstruction at the Single Capillary Level.

scientific article published on 14 June 2019

Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy.

scientific article

Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy.

scientific article published in March 2017

Real-time optical manipulation of cardiac conduction in intact hearts

scientific article published on 07 August 2018

Reply to Entcheva: The impact of T-tubules on action potential propagation in cardiac tissue.

scientific article

Second-harmonic generation sensitivity to transmembrane potential in normal and tumor cells.

scientific article published in March 2005

T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.

scientific article

The connectomics challenge

scientific article

The theory of pattern formation on directed networks ⬇️

scientific article published in Nature Communications

Three-dimensional magneto-optic trap for micro-object manipulation

scientific article published on 01 September 2001

Towards a comprehensive understanding of brain machinery by correlative microscopy.

scientific article published on June 2015

Two-photon microscopy imaging of thy1GFP-M transgenic mice: a novel animal model to investigate brain dendritic cell subsets in vivo

scientific article (publication date: 2013)

Universal autofocus for quantitative volumetric microscopy of whole mouse brains

scientific article published in 2021

Universal mechanisms for self-termination of rapid cardiac rhythm

scientific article published on 01 December 2020

Whole-Brain Vasculature Reconstruction at the Single Capillary Level

scientific article published in Scientific Reports

List of works by Leonardo Sacconi

A Software Architecture to Mimic a Ventricular Tachycardia in Intact Murine Hearts by Means of an All-Optical Platform

A versatile clearing agent for multi-modal brain imaging

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

Analysis of kinetics in noisy systems: application to single molecule tethered particle motion.

Cardiac sympathetic innervation network shapes the myocardium by locally controlling cardiomyocyte size through the cellular proteolytic machinery

Cell imaging and manipulation by nonlinear optical microscopy.

Clearing of fixed tissue: a review from a microscopist's perspective.

Comprehensive optical and data management infrastructure for high-throughput light-sheet microscopy of whole mouse brains

Computer-based automatic identification of neurons in gigavoxel-sized 3D human brain images

Confocal light sheet microscopy: micron-scale neuroanatomy of the entire mouse brain ⬇️

Confocal multispot microscope for fast and deep imaging in semicleared tissues

Correcting spherical aberrations in confocal light sheet microscopy: a theoretical study.

Correlative two-photon and light sheet microscopy.

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure

Electrical defects of the transverse-axial tubular system in cardiac diseases

Exploring molecular motors and switches at the single-molecule level.

Functional cardiac imaging by random access microscopy

Impact of detubulation on force and kinetics of cardiac muscle contraction.

In vivo multiphoton nanosurgery on cortical neurons.

In vivo single branch axotomy induces GAP-43-dependent sprouting and synaptic remodeling in cerebellar cortex.

Label-free near-infrared reflectance microscopy as a complimentary tool for two-photon fluorescence brain imaging

Laser nanosurgery of cerebellar axons in vivo

Letter to the Editor

Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair

Micron-scale resolution optical tomography of entire mouse brains with confocal light sheet microscopy

Multi-Modal Optical Imaging of the Cerebellum in Animals

Multi-photon nanosurgery in live brain.

Multiphoton multifocal microscopy exploiting a diffractive optical element

New techniques in linear and non-linear laser optics in muscle research.

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

Nuclear and division-plane positioning revealed by optical micromanipulation

Optical micromanipulations inside yeast cells.

Optical recording of fast neuronal membrane potential transients in acute mammalian brain slices by second-harmonic generation microscopy.

Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation.

Optogenetics gets to the heart: A guiding light beyond defibrillation

Overcoming photodamage in second-harmonic generation microscopy: real-time optical recording of neuronal action potentials.

Palette of fluorinated voltage-sensitive hemicyanine dyes

Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.

Positioning and elongation of the fission yeast spindle by microtubule-based pushing.

Probing myosin structural conformation in vivo by second-harmonic generation microscopy.

Protein conformation and molecular order probed by second-harmonic-generation microscopy.

Publisher Correction: Whole-Brain Vasculature Reconstruction at the Single Capillary Level.

Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy.

Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy.

Real-time optical manipulation of cardiac conduction in intact hearts

Reply to Entcheva: The impact of T-tubules on action potential propagation in cardiac tissue.

Second-harmonic generation sensitivity to transmembrane potential in normal and tumor cells.

T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.

The connectomics challenge

The theory of pattern formation on directed networks ⬇️

Three-dimensional magneto-optic trap for micro-object manipulation

Towards a comprehensive understanding of brain machinery by correlative microscopy.

Two-photon microscopy imaging of thy1GFP-M transgenic mice: a novel animal model to investigate brain dendritic cell subsets in vivo

Universal autofocus for quantitative volumetric microscopy of whole mouse brains

Universal mechanisms for self-termination of rapid cardiac rhythm

Whole-Brain Vasculature Reconstruction at the Single Capillary Level