List of works - Dorothy Bennett

A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds

scientific article

A role for ATF2 in regulating MITF and melanoma development

scientific article

ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

scientific journal article

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway

scientific article published on 26 May 2009

BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers

scientific article

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles

scientific article

BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery

scientific article

BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation

scientific article

Cancer cell senescence: a new frontier in drug development.

scientific article published on 31 January 2012

Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models

scientific article published on April 2014

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition

scientific article

Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes

scientific article

Cellular Senescence: Defining a Path Forward

scientific article published on 01 October 2019

Comment on “Absence of Senescence-Associated β-Galactosidase Activity in Human Melanocytic Nevi In Vivo”

scientific article published on 01 June 2008

Common Delayed Senescence of Melanocytes from Multiple Primary Melanoma Patients

scientific article published on 28 October 2016

Common variants in FOXP1 are associated with generalized vitiligo.

scientific article

Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP.

scientific article

Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes

scientific article

Dissection of RAS downstream pathways in melanomagenesis: a role for Ral in transformation.

scientific article published on February 2010

Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17

scientific article

EMX homeobox genes regulate microphthalmia and alter melanocyte biology

scientific article published on 27 September 2005

ETS1, nucleolar and non-nucleolar TERT expression in nevus to melanoma progression

scientific article published in November 2017

Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells

scientific article

Genetics of melanoma progression: the rise and fall of cell senescence

scientific article published on 19 September 2015

Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset

scientific article

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

scientific journal article

Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants

scientific article published on 10 October 2016

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

scientific article

Gpnmb is a melanoblast-expressed, MITF-dependent gene

scientific article

HLA class II haplotype DRB104-DQB10301 contributes to risk of familial generalized vitiligo and early disease onset

scientific article published on 01 February 2006

How to make a melanoma: what do we know of the primary clonal events?

scientific article published on February 2008

In vitro behavior and UV response of melanocytes derived from carriers of CDKN2A mutations and MC1R variants

scientific article published on 05 September 2018

Koebner's phenomenon in vitiligo: European position paper

scientific article

Mahogunin Ring Finger 1 Is Required for Genomic Stability and Modulates the Malignant Phenotype of Melanoma Cells

scientific article published on 01 October 2020

Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression

scientific article published on 20 April 2011

Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal

scientific article (publication date: October 2014)

Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL expression

scientific article published on 11 April 2014

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

scientific article published on June 2013

Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo.

scientific article

Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective

scientific article

PTPN22 is genetically associated with risk of generalized vitiligo, but CTLA4 is not.

scientific article

Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes

scientific article

Receptor tyrosine kinases and their activation in melanoma.

scientific article published on 03 March 2011

Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence

scientific article published on August 2013

Senescence evasion in melanoma progression: uncoupling of DNA-damage signaling from p53 activation and p21 expression

scientific article published on 14 January 2013

Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells

scientific article

Stochastic E2F activation and reconciliation of phenomenological cell-cycle models

scientific article

Targeting protein-trafficking pathways alters melanoma treatment sensitivity

scientific article published on 27 December 2011

The human TPR protein TTC4 is a putative Hsp90 co-chaperone which interacts with CDC6 and shows alterations in transformed cells

scientific article

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells

scientific article

Ultraviolet wavebands and melanoma initiation.

scientific article published in October 2008

V600EBraf::Tyr-CreERT2::K14-Kitl Mice Do Not Develop Superficial Spreading-Like Melanoma: Keratinocyte Kit Ligand Is Insufficient to “Translocate” V600EBraf-Driven Melanoma to the Epidermis

article

Vitiligo-associated multiple autoimmune disease is not associated with genetic variation in AIRE

scientific article published on 01 October 2007

List of works by Dorothy Bennett

A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds

A role for ATF2 in regulating MITF and melanoma development

ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway

BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers

BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles

BLOC-2 targets recycling endosomal tubules to melanosomes for cargo delivery

BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation

Cancer cell senescence: a new frontier in drug development.

Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition

Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes

Cellular Senescence: Defining a Path Forward

Comment on “Absence of Senescence-Associated β-Galactosidase Activity in Human Melanocytic Nevi In Vivo”

Common Delayed Senescence of Melanocytes from Multiple Primary Melanoma Patients

Common variants in FOXP1 are associated with generalized vitiligo.

Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP.

Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes

Dissection of RAS downstream pathways in melanomagenesis: a role for Ral in transformation.

Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17

EMX homeobox genes regulate microphthalmia and alter melanocyte biology

ETS1, nucleolar and non-nucleolar TERT expression in nevus to melanoma progression

Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells

Genetics of melanoma progression: the rise and fall of cell senescence

Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo

Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants

Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes

Gpnmb is a melanoblast-expressed, MITF-dependent gene

HLA class II haplotype DRB1*04-DQB1*0301 contributes to risk of familial generalized vitiligo and early disease onset

How to make a melanoma: what do we know of the primary clonal events?

In vitro behavior and UV response of melanocytes derived from carriers of CDKN2A mutations and MC1R variants

Koebner's phenomenon in vitiligo: European position paper

Mahogunin Ring Finger 1 Is Required for Genomic Stability and Modulates the Malignant Phenotype of Melanoma Cells

Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression

Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal

Melanosome-autonomous regulation of size and number: the OA1 receptor sustains PMEL expression

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo.

Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective

PTPN22 is genetically associated with risk of generalized vitiligo, but CTLA4 is not.

Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes

Receptor tyrosine kinases and their activation in melanoma.

Redistribution of the Lamin B1 genomic binding profile affects rearrangement of heterochromatic domains and SAHF formation during senescence

Senescence evasion in melanoma progression: uncoupling of DNA-damage signaling from p53 activation and p21 expression

Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells

Stochastic E2F activation and reconciliation of phenomenological cell-cycle models

Targeting protein-trafficking pathways alters melanoma treatment sensitivity

The human TPR protein TTC4 is a putative Hsp90 co-chaperone which interacts with CDC6 and shows alterations in transformed cells

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells

Ultraviolet wavebands and melanoma initiation.

V600EBraf::Tyr-CreERT2::K14-Kitl Mice Do Not Develop Superficial Spreading-Like Melanoma: Keratinocyte Kit Ligand Is Insufficient to “Translocate” V600EBraf-Driven Melanoma to the Epidermis

Vitiligo-associated multiple autoimmune disease is not associated with genetic variation in AIRE

HLA class II haplotype DRB104-DQB10301 contributes to risk of familial generalized vitiligo and early disease onset