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List of works by Istvan Baczko

A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene.

scientific article published on 14 April 2016

ATP-sensitive potassium channel modulators and cardiac arrhythmias: an update.

scientific article

ATP-sensitive potassium channel modulators: both pinacidil and glibenclamide produce antiarrhythmic activity during acute myocardial infarction in conscious rats

scientific article published on 01 June 1996

Altered expression of genes for Kir ion channels in dilated cardiomyopathy.

scientific article published on 4 March 2013

Antiarrhythmic and cardiac electrophysiological effects of SZV-270, a novel compound with combined Class I/B and Class III effects, in rabbits and dogs

scientific article published on 24 September 2020

Antiarrhythmic and electrophysiological effects of GYKI-16638, a novel N-(phenoxyalkyl)-N-phenylalkylamine, in rabbits.

scientific article published in September 2000

Capsaicin-Sensitive Sensory Nerves and the TRPV1 Ion Channel in Cardiac Physiology and Pathologies

scientific article published on 23 June 2020

Cardiac ventricular repolarization reserve: a principle for understanding drug-related proarrhythmic risk.

scientific article

Cardioprotection and arrhythmias, Part 2

scientific article published on 01 September 2015

Cardioprotection and arrhythmias, Part I

scientific article published on 01 July 2015

Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation.

scientific article published on January 2014

Class I/B antiarrhythmic property of ranolazine, a novel antianginal agent, in dog and human cardiac preparations.

scientific article

Combined inhibition of key potassium currents has different effects on cardiac repolarization reserve and arrhythmia susceptibility in dogs and rabbits.

scientific article

Combined pharmacological block of I(Kr) and I(Ks) increases short-term QT interval variability and provokes torsades de pointes.

scientific article

Comparison of the effects of IK,ACh, IKr, and INa block in conscious dogs with atrial fibrillation and on action potentials in remodeled atrial trabeculae.

scientific article published on 11 September 2017

Comparison of the efficacy of glibenclamide and glimepiride in reperfusion-induced arrhythmias in rats.

scientific article published in January 1999

Contribution of I Kr and I K1 to ventricular repolarization in canine and human myocytes: is there any influence of action potential duration?

scientific article published on 05 July 2008

Coxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia

scientific article

Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications

scientific article published on 01 June 2019

Diastolic calcium is elevated in metabolic recovery of cardiomyocytes expressing elevated levels of the Na+/H+ exchanger.

scientific article

Diclofenac prolongs repolarization in ventricular muscle with impaired repolarization reserve

scientific article

Distinct early signaling events resulting from the expression of the PRKAG2 R302Q mutant of AMPK contribute to increased myocardial glycogen.

scientific article published on 15 July 2009

Effect of glibenclamide and glimepiride treatment on the development of myocardial infarction in rats

scientific article published on 01 January 2000

Effects of aging on cardiac extracellular matrix in men and women

scientific article published on 17 August 2015

Effects of diclofenac on ventricular muscle repolarization: proarrhythmic implications.

scientific article

Electrical Restitution and Its Modifications by Antiarrhythmic Drugs in Undiseased Human Ventricular Muscle

scientific article published on 30 April 2020

Electrophysiological effects of ivabradine in dog and human cardiac preparations: Potential antiarrhythmic actions

scientific article published on 02 August 2011

Future perspectives in the pharmacological treatment of atrial fibrillation and ventricular arrhythmias in heart failure

scientific article

Genome-wide identification of expression quantitative trait loci (eQTLs) in human heart

scientific article

Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion

scientific article published on 26 February 2020

Identification of optimal reference genes for transcriptomic analyses in normal and diseased human heart

scientific article published on 22 September 2017

Increased Short-Term Beat-To-Beat Variability of QT Interval in Patients with Acromegaly

scientific article published on 27 April 2015

Increased Short-Term Beat-to-Beat QT Interval Variability in Patients with Impaired Glucose Tolerance

scientific article

Increased short-term variability of the QT interval in professional soccer players: possible implications for arrhythmia prediction.

scientific article

Inhibition of cardiac voltage-gated sodium channels by grape polyphenols.

scientific article published on 3 October 2006

Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte.

scientific article published on 10 December 2007

KATP channel modulators increase survival rate during coronary occlusion-reperfusion in anaesthetized rats.

scientific article published in April 1997

Late sodium current in human, canine and guinea pig ventricular myocardium

scientific article published on 17 January 2020

Localization and functional consequences of a direct interaction between TRIOBP-1 and hERG proteins in the heart.

scientific article published on 5 March 2018

Long-term endurance training-induced cardiac adaptation in new rabbit and dog animal models of the human athlete's heart

scientific article published on 01 December 2018

Long-term pretreatment with desethylamiodarone (DEA) or amiodarone (AMIO) protects against coronary artery occlusion induced ventricular arrhythmias in conscious rats

scientific article published on 02 April 2015

Measurements of electrophysiological effects of components of acute ischemia in Langendorff-perfused rat hearts using voltage-sensitive dye mapping

Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs.

scientific article

Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues.

scientific article published on 30 June 2015

Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy.

scientific article published on 7 December 2017

Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.

scientific article published on 07 December 2016

Plasma membrane KATP channel-mediated cardioprotection involves posthypoxic reductions in calcium overload and contractile dysfunction: mechanistic insights into cardioplegia.

scientific article published on 16 March 2005

Possible mechanisms of sudden cardiac death in top athletes: a basic cardiac electrophysiological point of view

scientific article published on 26 February 2010

Properties of the transient outward, ultra-rapid delayed rectifier and acetylcholine-sensitive potassium currents in isolated atrial myocytes from dogs: sinus rhythm and tachypaced model of permanent atrial fibrillation.

scientific article published on 5 September 2011

Rabbit models as tools for preclinical cardiac electrophysiological safety testing: Importance of repolarization reserve.

scientific article published on 18 May 2016

Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation"

scientific article published on 01 March 2016

Resting membrane potential regulates Na(+)-Ca2+ exchange-mediated Ca2+ overload during hypoxia-reoxygenation in rat ventricular myocytes.

scientific article

Resveratrol and derivatives for the treatment of atrial fibrillation.

scientific article published on 23 July 2015

Sarcolemmal Ca(2+)-entry through L-type Ca(2+) channels controls the profile of Ca(2+)-activated Cl(-) current in canine ventricular myocytes.

scientific article

Selective Pharmacological Inhibition of the Pacemaker Channel Isoforms (HCN1-4) as New Possible Therapeutical Targets ⬇️

scientific article published on January 1, 2011

Selective cardiac plasma-membrane K(ATP) channel inhibition is defibrillatory and improves survival during acute myocardial ischemia and reperfusion.

scientific article published on 19 August 2007

Sex differences in the aging human heart: decreased sirtuins, pro-inflammatory shift and reduced anti-oxidative defense

scientific article published on 01 April 2019

Sex-dependent regulation of fibrosis and inflammation in human left ventricular remodelling under pressure overload

scientific article published on 7 October 2014

Short-term beat-to-beat variability of the QT interval is increased and correlates with parameters of left ventricular hypertrophy in patients with hypertrophic cardiomyopathy.

scientific article

The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments

scientific article

The potential impact of new generation transgenic methods on creating rabbit models of cardiac diseases.

scientific article published on 19 May 2016

Transcriptome characterization of estrogen-treated human myocardium identifies myosin regulatory light chain interacting protein as a sex-specific element influencing contractile function

scientific article published in January 2012

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