List of works - Thierry Louat

Atypical protein kinase C stimulates nucleotide excision repair activity.

scientific article published on September 2004

Comparative In Vitro Immune Stimulation Analysis of Primary Human B Cells and B Cell Lines.

scientific article published on 26 December 2016

Discovery of 7-N-Piperazinylthiazolo[5,4-d]pyrimidine Analogues as a Novel Class of Immunosuppressive Agents with in Vivo Biological Activity

Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo

scientific article published on 19 July 2018

High dose of prebiotics reduces fecal water cytotoxicity in healthy subjects

scientific article published on 17 October 2014

Modulation of protein fermentation does not affect fecal water toxicity: a randomized cross-over study in healthy subjects

scientific article

OSU-T315 as an Interesting Lead Molecule for Novel B Cell-Specific Therapeutics

scientific article published on 12 September 2018

Overexpression of protein kinase Czeta confers protection against antileukemic drugs by inhibiting the redox-dependent sphingomyelinase activation.

scientific article published on December 2002

Prevalence of BRCA1 and BRCA2 germline mutations in young breast cancer patients: a population-based study.

scientific article

Structure-based drug repositioning explains ibrutinib as VEGFR2 inhibitor

scientific article published on 27 May 2020

Synthesis and Immunosuppressive Activity of New Mycophenolic Acid Derivatives.

scientific article published on 7 December 2016

Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis

scientific article published on 9 June 2011

Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis.

scientific article

Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay

scientific article

Synthesis, immunosuppressive activity and structure-activity relationship study of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidine analogues

scientific article published on 4 January 2010

Wheat bran extract alters colonic fermentation and microbial composition, but does not affect faecal water toxicity: a randomised controlled trial in healthy subjects

scientific article published on 12 December 2014

hMutS alpha is protected from ubiquitin-proteasome-dependent degradation by atypical protein kinase C zeta phosphorylation

scientific article

γ-Hydroxyethyl piperidine iminosugar and N-alkylated derivatives: a study of their activity as glycosidase inhibitors and as immunosuppressive agents

scientific article published on 7 October 2014

List of works by Thierry Louat

Atypical protein kinase C stimulates nucleotide excision repair activity.

Comparative In Vitro Immune Stimulation Analysis of Primary Human B Cells and B Cell Lines.

Discovery of 7-N-Piperazinylthiazolo[5,4-d]pyrimidine Analogues as a Novel Class of Immunosuppressive Agents with in Vivo Biological Activity

Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo

High dose of prebiotics reduces fecal water cytotoxicity in healthy subjects

Modulation of protein fermentation does not affect fecal water toxicity: a randomized cross-over study in healthy subjects

OSU-T315 as an Interesting Lead Molecule for Novel B Cell-Specific Therapeutics

Overexpression of protein kinase Czeta confers protection against antileukemic drugs by inhibiting the redox-dependent sphingomyelinase activation.

Prevalence of BRCA1 and BRCA2 germline mutations in young breast cancer patients: a population-based study.

Structure-based drug repositioning explains ibrutinib as VEGFR2 inhibitor

Synthesis and Immunosuppressive Activity of New Mycophenolic Acid Derivatives.

Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis

Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis.

Synthesis of a 2,4,6-trisubstituted 5-cyano-pyrimidine library and evaluation of its immunosuppressive activity in a Mixed Lymphocyte Reaction assay

Synthesis, immunosuppressive activity and structure-activity relationship study of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidine analogues

Wheat bran extract alters colonic fermentation and microbial composition, but does not affect faecal water toxicity: a randomised controlled trial in healthy subjects

hMutS alpha is protected from ubiquitin-proteasome-dependent degradation by atypical protein kinase C zeta phosphorylation

γ-Hydroxyethyl piperidine iminosugar and N-alkylated derivatives: a study of their activity as glycosidase inhibitors and as immunosuppressive agents