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List of works by Cristina Saura

A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors

scientific article published on 21 November 2016

A multicenter trial evaluating retaspimycin HCL (IPI-504) plus trastuzumab in patients with advanced or metastatic HER2-positive breast cancer

scientific article published on 12 April 2013

A novel de novo BRCA2 mutation of paternal origin identified in a Spanish woman with early onset bilateral breast cancer

scientific article

A phase II pharmacodynamic study of erlotinib in patients with advanced non-small cell lung cancer previously treated with platinum-based chemotherapy

scientific article published in June 2008

A phase Ib, open-label, dose-escalation study of the safety and pharmacology of taselisib (GDC-0032) in combination with either docetaxel or paclitaxel in patients with HER2-negative, locally advanced, or metastatic breast cancer

scientific article published on 31 July 2019

Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis

scientific article published on 04 October 2011

Biomarker analysis of neoadjuvant doxorubicin/cyclophosphamide followed by ixabepilone or Paclitaxel in early-stage breast cancer

scientific article published on 22 January 2013

Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle

scientific article published on 01 November 2018

Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle.

scientific article published on 09 July 2014

Clinical consequences of BRCA2 hypomorphism

publication published on 09 September 2021

Effect of body mass index on response to neo-adjuvant therapy in HER2-positive breast cancer: an exploratory analysis of the NeoALTTO trial

scientific article published on 27 October 2020

Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer

scientific article published on 05 December 2019

Evaluation and clinical analyses of downstream targets of the Akt inhibitor GDC-0068.

scientific article published on 18 October 2013

FAIRLANE, a double-blind placebo-controlled randomized phase II trial of neoadjuvant ipatasertib plus paclitaxel for early triple-negative breast cancer

scientific article published on 01 August 2019

GDF15 Is an Eribulin Response Biomarker also Required for Survival of DTP Breast Cancer Cells

scientific article published on 23 May 2022

Gemcitabine and capecitabine in previously anthracycline-treated metastatic breast cancer: a multicenter phase II study (SOLTI 0301 trial).

scientific article published on 25 November 2009

Genetic alterations in the PI3K/AKT pathway and baseline AKT activity define AKT inhibitor sensitivity in breast cancer patient-derived xenografts

scientific article published on 27 March 2020

Genomic alterations in breast cancer: level of evidence for actionability according to ESMO Scale for Clinical Actionability of molecular Targets (ESCAT)

scientific article published on 01 March 2019

HER2 and hormone receptor-positive breast cancer--blocking the right target

scientific article published on 14 December 2010

Impact of FDG PET Imaging for Expanding Patient Eligibility and Measuring Treatment Response in a Genome-Driven Basket Trial of the Pan-HER Kinase Inhibitor, Neratinib

scientific article published on 23 September 2019

Lack of Efficacy of Streptozocin and Doxorubicin in Patients With Advanced Pancreatic Endocrine Tumors

scientific article published on 01 August 2005

Management of the axilla in early breast cancer patients in the genomic era.

scientific article

Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines

scientific article published on 21 October 2008

Molecular prescreening to select patient population in early clinical trials

scientific article published on 03 April 2012

Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.

scientific article

Monoclonal antibodies in the treatment of advanced colorectal cancer.

scientific article published on 5 November 2007

Multidisciplinary approach to breast cancer diagnosed during pregnancy: Maternal and neonatal outcomes

scientific article published on 30 October 2012

Neoadjuvant Management of Early Breast Cancer: A Clinical and Investigational Position Statement

scientific article published on 01 February 2019

Neoadjuvant doxorubicin/cyclophosphamide followed by ixabepilone or paclitaxel in early stage breast cancer and evaluation of βIII-tubulin expression as a predictive marker.

scientific article published on 12 July 2013

Neratinib plus capecitabine for the treatment of advanced HER2-positive breast cancer

scientific article published on 30 August 2020

POSEIDON Trial Phase 1b Results: Safety, Efficacy and Circulating Tumor DNA Response of the Beta Isoform-Sparing PI3K Inhibitor Taselisib (GDC-0032) Combined with Tamoxifen in Hormone Receptor Positive Metastatic Breast Cancer Patients

scientific article published on 22 August 2019

Phase I Basket Study of Taselisib, an Isoform-Selective PI3K Inhibitor, in Patients with PIK3CA-Mutant Cancers

scientific article published on 04 November 2020

Phase I trial of olaparib in combination with cisplatin for the treatment of patients with advanced breast, ovarian and other solid tumors

article

Phase I/II study of pilaralisib (SAR245408) in combination with trastuzumab or trastuzumab plus paclitaxel in trastuzumab-refractory HER2-positive metastatic breast cancer.

scientific article

Phase II study of buparlisib (BKM120) and trastuzumab in patients with HER2+ locally advanced or metastatic breast cancer resistant to trastuzumab-based therapy

scientific article published on 2 December 2017

Phase Ib study of Buparlisib plus Trastuzumab in patients with HER2-positive advanced or metastatic breast cancer that has progressed on Trastuzumab-based therapy

scientific article published on 27 January 2014

Risk of Venous Thromboembolism With Bevacizumab in Cancer Patients

scientific article published in The Journal of the American Medical Association

SEOM clinical guidelines in metastatic breast cancer 2015.

scientific article

Safety and efficacy of neratinib in combination with capecitabine in patients with metastatic human epidermal growth factor receptor 2-positive breast cancer.

scientific article published on 6 October 2014

Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer: a phase 1 dose-escalation and dose-expansion study

scientific article published on 27 June 2019

Trastuzumab-related cardiotoxicity in the elderly: a role for cardiovascular risk factors

scientific article published on 09 August 2011

p95HER2-T cell bispecific antibody for breast cancer treatment

scientific article published on 01 October 2018

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