Search filters

List of works by Lutz Nuhn

A Fully Synthetic Glycopeptide Antitumor Vaccine Based on Multiple Antigen Presentation on a Hyperbranched Polymer

scientific article published on 12 March 2014

A Generic Polymer-Protein Ligation Strategy for Vaccine Delivery

scientific article published on 26 January 2016

A Synthetic, Transiently Thermoresponsive Homopolymer with UCST Behaviour within a Physiologically Relevant Window

scientific article published on 30 April 2019

A Tribute to Rudolf Zentel and His Lifetime Research Achievements

academic paper published in 2022

Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization

Aggregation Behavior of Cationic Nanohydrogel Particles in Human Blood Serum

scientific article published on 03 April 2014

Cancer Cell Lysate Entrapment in CaCO3 Engineered with Polymeric TLR-Agonists: Immune-Modulating Microparticles in View of Personalized Antitumor Vaccination

Cationic Nanohydrogel Particles for Therapeutic Oligonucleotide Delivery

scientific article

Cationic nanohydrogel particles as potential siRNA carriers for cellular delivery

scientific article

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

scientific article

Combining Ring-Opening Multibranching and RAFT Polymerization: Multifunctional Linear–Hyperbranched Block Copolymers via Hyperbranched Macro-Chain-Transfer Agents

Control over Imidazoquinoline Immune Stimulation by pH-Degradable Poly(norbornene) Nanogels

scientific article published on 07 April 2020

Core/shell protein-reactive nanogels via a combination of RAFT polymerization and vinyl sulfone postmodification

scientific article published on 15 September 2016

CpG-loaded multifunctional cationic nanohydrogel particles as self-adjuvanting glycopeptide antitumor vaccines

scientific article published on 18 October 2014

DNA-Polymer Nanostructures by RAFT Polymerization and Polymerization-Induced Self-Assembly

scientific article published on 17 April 2020

Degradable Cationic Nanohydrogel Particles for Stimuli-Responsive Release of siRNA

scientific article published on 17 October 2014

Degradable cationic nanohydrogel particles for stimuli-responsive release of siRNA

Design of pH-Degradable Polymer-Lipid Amphiphiles Using a Ketal-Functionalized RAFT Chain Transfer Agent

scientific article published on 10 March 2020

Downstream processing from hot-melt extrusion towards tablets: A quality by design approach

scientific article

FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles

scientific article published on 25 July 2018

Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity

Immunoengineering through cancer vaccines – A personalized and multi-step vaccine approach towards precise cancer immunity

In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles

scientific article published on 2 December 2015

In Vivo Myofibroblast Specific Gene Silencing in the Liver Using Novel Sirna-Loaded Biodegradable Nanohydrogel Particles

article

In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles

scientific article published on 15 August 2020

Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination

scientific article published on 29 January 2016

Linear-Hyperbranched Graft-Copolymers via Grafting-to Strategy Based on Hyperbranched Dendron Analogues and Reactive Ester Polymers

Lymph node targeted immune-activation by engineered block copol-ymer amphiphiles - TLR7/8 agonist conjugates

scientific article published in 2018

Micellar Paclitaxel-Initiated RAFT Polymer Conjugates with Acid-Sensitive Behavior

Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

New Perspectives of HPMA-based Copolymers Derived by Post-Polymerization Modification

scientific article published on 19 March 2014

New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes.

scientific article published on 9 December 2014

Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine

scientific article published on 08 October 2015

Novel Opportunities for Cathepsin S Inhibitors in Cancer Immunotherapy by Nanocarrier-Mediated Delivery

scientific article published on 02 September 2020

P0419 : In vivo cell specific gene silencing in the liver using novel siRNA-loaded nanohydrogel particles

article

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists

scientific article published on 12 September 2019

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist.

scientific article

RAFT-polymerized poly(hexafluoroisopropyl methacrylate)s as precursors for functional water-soluble polymers

Reductive Decationizable Block Copolymers for Stimuli-Responsive mRNA Delivery

scientific article published on 14 April 2016

SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles

scientific article published on 8 December 2016

Size-dependent knockdown potential of siRNA-loaded cationic nanohydrogel particles

scientific article published on 22 October 2014

Squaric ester amides as hydrolysis-resistant functional groups for protein-conjugation of RAFT-derived polymers

Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*

scientific article

Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine

scientific article published on 23 October 2020

Supramolecular Linear-g-Hyperbranched Graft Polymers: Topology and Binding Strength of Hyperbranched Side Chains

scientific article published on 3 December 2013

Synthetic Rhamnose Glycopolymer Cell-Surface Receptor for Endogenous Antibody Recruitment

scientific article published on 08 January 2020

Synthetisch hergestellte, transient thermoresponsive Homopolymere mit einer oberen kritischen Lösungstemperatur für physiologisch relevante Anwendungen

Targeting Protumoral Tumor-Associated Macrophages with Nanobody-Functionalized Nanogels through Strain Promoted Azide Alkyne Cycloaddition Ligation

scientific article published on 28 June 2018

The Protein Corona as a Confounding Variable of Nanoparticle-Mediated Targeted Vaccine Delivery

Thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis.

scientific article

Transient Multivalent Nanobody Targeting to CD206-Expressing Cells via PH-Degradable Nanogels

scientific article published on 01 October 2020

Transiently Responsive Block Copolymer Micelles Based on N-(2-Hydroxypropyl)methacrylamide Engineered with Hydrolyzable Ethylcarbonate Side Chains

scientific article published on 9 December 2015

Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant.

scientific article published on 26 November 2017

Transiently thermoresponsive polymers and their applications in biomedicine.

scientific article published on 6 February 2017

Tunable dynamic hydrophobic attachment of guest molecules in amphiphilic core–shell polymers

article published in 2016

Water-soluble polymers coupled with glycopeptide antigens and T-cell epitopes as potential antitumor vaccines

scientific article published on 26 August 2013

Well-Defined Polymer-Paclitaxel Prodrugs by a Grafting-from-Drug Approach

scientific article published on 25 August 2016

pH-Degradable Mannosylated Nanogels for Dendritic Cell Targeting

scientific article

pH-Sensitive Hydrazone-Linked Doxorubicin Nanogels via Polymeric-Activated Ester Scaffolds: Synthesis, Assembly, and In Vitro and In Vivo Evaluation in Tumor-Bearing Zebrafish

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

scientific article published on 05 July 2016

α-Mannosyl-Functionalized Cationic Nanohydrogel Particles for Targeted Gene Knockdown in Immunosuppressive Macrophages

scientific article published on 07 June 2019

Paulina is supported by:

About Paulina

Help