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List of works by Lutz Nuhn

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Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

scientific article
pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

scientific article published on 05 July 2016
Water-soluble polymers coupled with glycopeptide antigens and T-cell epitopes as potential antitumor vaccines

scientific article published on 26 August 2013
CpG-loaded multifunctional cationic nanohydrogel particles as self-adjuvanting glycopeptide antitumor vaccines

scientific article published on 18 October 2014
Cationic nanohydrogel particles as potential siRNA carriers for cellular delivery

scientific article
Size-dependent knockdown potential of siRNA-loaded cationic nanohydrogel particles

scientific article published on 22 October 2014
In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles

scientific article published on 2 December 2015
Aggregation Behavior of Cationic Nanohydrogel Particles in Human Blood Serum

scientific article published on 03 April 2014
Reductive Decationizable Block Copolymers for Stimuli-Responsive mRNA Delivery

scientific article published on 14 April 2016
Well-Defined Polymer-Paclitaxel Prodrugs by a Grafting-from-Drug Approach

scientific article published on 25 August 2016
A Fully Synthetic Glycopeptide Antitumor Vaccine Based on Multiple Antigen Presentation on a Hyperbranched Polymer

scientific article published on 12 March 2014
pH-Degradable Mannosylated Nanogels for Dendritic Cell Targeting

scientific article
Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine

scientific article published on 08 October 2015
Targeting Protumoral Tumor-Associated Macrophages with Nanobody-Functionalized Nanogels through Strain Promoted Azide Alkyne Cycloaddition Ligation

scientific article published on 28 June 2018
Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

Lymph node targeted immune-activation by engineered block copol-ymer amphiphiles - TLR7/8 agonist conjugates

scientific article published in 2018
New Perspectives of HPMA-based Copolymers Derived by Post-Polymerization Modification

scientific article published on 19 March 2014
Transiently Responsive Block Copolymer Micelles Based on N-(2-Hydroxypropyl)methacrylamide Engineered with Hydrolyzable Ethylcarbonate Side Chains

scientific article published on 9 December 2015
Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses

Transiently thermoresponsive polymers and their applications in biomedicine.

scientific article published on 6 February 2017
New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes.

scientific article published on 9 December 2014
A Generic Polymer-Protein Ligation Strategy for Vaccine Delivery

scientific article published on 26 January 2016
The Protein Corona as a Confounding Variable of Nanoparticle-Mediated Targeted Vaccine Delivery

Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination

scientific article published on 29 January 2016
Cationic Nanohydrogel Particles for Therapeutic Oligonucleotide Delivery

scientific article
Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

scientific article
Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant.

scientific article published on 26 November 2017
Degradable cationic nanohydrogel particles for stimuli-responsive release of siRNA

Thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis.

scientific article
Downstream processing from hot-melt extrusion towards tablets: A quality by design approach

scientific article
SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles

scientific article published on 8 December 2016
Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity

Supramolecular Linear-g-Hyperbranched Graft Polymers: Topology and Binding Strength of Hyperbranched Side Chains

scientific article published on 3 December 2013
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*

scientific article
Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists

scientific article published on 12 September 2019
α-Mannosyl-Functionalized Cationic Nanohydrogel Particles for Targeted Gene Knockdown in Immunosuppressive Macrophages

scientific article published on 07 June 2019
Degradable Cationic Nanohydrogel Particles for Stimuli-Responsive Release of siRNA

scientific article published on 17 October 2014
Tunable dynamic hydrophobic attachment of guest molecules in amphiphilic core–shell polymers

article published in 2016
pH-Sensitive Hydrazone-Linked Doxorubicin Nanogels via Polymeric-Activated Ester Scaffolds: Synthesis, Assembly, and In Vitro and In Vivo Evaluation in Tumor-Bearing Zebrafish

In Vivo Myofibroblast Specific Gene Silencing in the Liver Using Novel Sirna-Loaded Biodegradable Nanohydrogel Particles

article
Design of pH-Degradable Polymer-Lipid Amphiphiles Using a Ketal-Functionalized RAFT Chain Transfer Agent

scientific article published on 10 March 2020
Core/shell protein-reactive nanogels via a combination of RAFT polymerization and vinyl sulfone postmodification

scientific article published on 15 September 2016
Cancer Cell Lysate Entrapment in CaCO3 Engineered with Polymeric TLR-Agonists: Immune-Modulating Microparticles in View of Personalized Antitumor Vaccination

Immunoengineering through cancer vaccines – A personalized and multi-step vaccine approach towards precise cancer immunity

A Tribute to Rudolf Zentel and His Lifetime Research Achievements

academic paper published in 2022
Synthetisch hergestellte, transient thermoresponsive Homopolymere mit einer oberen kritischen Lösungstemperatur für physiologisch relevante Anwendungen

Control over Imidazoquinoline Immune Stimulation by pH-Degradable Poly(norbornene) Nanogels

scientific article published on 07 April 2020
RAFT-polymerized poly(hexafluoroisopropyl methacrylate)s as precursors for functional water-soluble polymers

Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization

FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles

scientific article published on 25 July 2018

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