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List of works by Pamela Bielli

ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence.

scientific article published on 09 August 2013

Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells.

scientific article published on 9 November 2017

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation

scientific article published on 24 March 2017

Analysis of in vivo Interaction between RNA Binding Proteins and Their RNA Targets by UV Cross-linking and Immunoprecipitation (CLIP) Method

scientific article published on May 2017

Assignment of the 1H, 13C and 15N resonances of Mlc1p from Saccharomices cerevisiae.

scientific article

DNA Damage Regulates the Functions of the RNA Binding Protein Sam68 through ATM-Dependent Phosphorylation

scientific article published in 2022

DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components.

scientific article

Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation.

scientific article

Functional Interaction between U1snRNP and Sam68 Insures Proper 3' End Pre-mRNA Processing during Germ Cell Differentiation

scientific article published on 01 March 2019

MIR retroposon exonization promotes evolutionary variability and generates species-specific expression of IGF-1 splice variants

scientific article published on 2 April 2016

Modulation of PKM alternative splicing by PTBP1 promotes gemcitabine resistance in pancreatic cancer cells.

scientific article published on 03 August 2015

Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells

scientific article published on 22 September 2008

Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5' splice site selection

scientific article published on 7 October 2014

Release of highly active Fet3 from membranes of the yeast Pichia pastoris by limited proteolysis.

scientific article published in December 1999

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization

scientific article published on 01 January 2020

Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing

scientific article

Splicing Dysregulation as Oncogenic Driver and Passenger Factor in Brain Tumors

scientific article published on 18 December 2019

The RNA-binding protein Sam68 is a multifunctional player in human cancer

scientific article (publication date: August 2011)

The Splicing Factor PTBP1 Promotes Expression of Oncogenic Splice Variants and Predicts Poor Prognosis in Patients with Non–muscle-Invasive Bladder Cancer

scientific article published on 16 July 2018

The emerging role of PTBP1 in human cancer: novel prognostic factor in non-muscle invasive bladder cancer

scientific article published on 01 December 2018

The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability

scientific article published on 15 April 2015

The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy

scientific article

The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis

scientific article

The transcriptional co-activator SND1 is a novel regulator of alternative splicing in prostate cancer cells

scientific article published on 2 September 2013

Ypt32p and Mlc1p bind within the vesicle binding region of the class V myosin Myo2p globular tail domain

scientific article published on 23 January 2008

c-MYC empowers transcription and productive splicing of the oncogenic splicing factor Sam68 in cancer

scientific article published on 01 July 2019

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

scientific article published on 24 March 2013