List of works - May Khanna

(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels

scientific article published on 20 December 2018

1H, 15N and 13C backbone assignment of apo TDP-43 RNA recognition motifs

scientific article published on 29 January 2019

A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B).

scientific article published on 6 September 2018

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors

scientific article published on July 2015

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.

scientific article

A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300.

scientific article

An Allosteric Modulator of RNA Binding Targeting the N-Terminal Domain of TDP-43 Yields Neuroprotective Properties

scientific article published on 12 October 2020

Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels

scientific article published on 06 August 2018

Design, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor

scientific article

Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins

scientific article published on 14 February 2020

Discovery and characterization of small molecules that target the GTPase Ral

scientific article

Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases

scientific article

Discovery of novel regulators of aldehyde dehydrogenase isoenzymes ⬇️

scientific article published on February 22, 2011

Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief

scientific article published on 01 December 2019

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.

scientific article published on 5 February 2017

Molecular biology: RNA in control

scientific article published in Nature

Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

scientific article

NMR studies of protein-RNA interactions

scientific article published on 01 January 2012

Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition

scientific article

Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)

scientific article published on 27 August 2019

Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase

scientific article

Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex

scientific article published on 5 June 2011

Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin

scientific article published in February 2002

Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell proliferation

scientific article

The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels

scientific article published on 21 November 2019

Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis

scientific article published on 4 October 2011

List of works by May Khanna

(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels

1H, 15N and 13C backbone assignment of apo TDP-43 RNA recognition motifs

A Chemical Biology Approach to Model Pontocerebellar Hypoplasia Type 1B (PCH1B).

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.

A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300.

An Allosteric Modulator of RNA Binding Targeting the N-Terminal Domain of TDP-43 Yields Neuroprotective Properties

Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels

Design, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor

Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins

Discovery and characterization of small molecules that target the GTPase Ral

Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases

Discovery of novel regulators of aldehyde dehydrogenase isoenzymes ⬇️

Evaluation of edonerpic maleate as a CRMP2 inhibitor for pain relief

Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.

Molecular biology: RNA in control

Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

NMR studies of protein-RNA interactions

Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition

Small Molecule Targeting TDP-43's RNA Recognition Motifs Reduces Locomotor Defects in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)

Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase

Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex

Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin

Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell proliferation

The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels

Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis