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List of works by Dirkjan Hijnen

'En route' to precision medicine

scientific article published on 01 March 2019

A panel of biomarkers for disease severity in atopic dermatitis

scientific article published on 01 March 2015

A woman with hyperpigmentations on the upper legs

scientific article

Absence of T-regulatory cell expression and function in atopic dermatitis skin

scientific article published on 01 January 2006

Acute arthritis and arthralgia as an adverse drug reaction to dupilumab

scientific article published on 06 September 2019

Allopurinol Co-prescription Improves the Outcome of Azathioprine Treatment in Chronic Eczema.

scientific article published on 14 November 2017

An approach for the transition from systemic immunosuppressants to dupilumab

scientific article published on 13 September 2020

Anti-IL-5 recombinant humanized monoclonal antibody (mepolizumab) for the treatment of atopic dermatitis.

scientific article published in May 2005

Atherosclerotic arterial remodeling and the localization of macrophages and matrix metalloproteases 1, 2 and 9 in the human coronary artery

scientific article published on 01 June 2000

Atopic dermatitis: A tale of two distinct pathomechanisms that make you itch.

scientific article published in November 2016

Biomarkers detected in dried blood spots from atopic dermatitis patients strongly correlate with disease severity

scientific article published on 05 August 2019

Biomarkers for atopic dermatitis: a systematic review and meta-analysis

scientific article published on 29 July 2015

Brief report: enrichment of activated group 3 innate lymphoid cells in psoriatic arthritis synovial fluid

scientific article published on 01 October 2015

CD8(+) T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-γ, IL-13, IL-17, and IL-22.

scientific article published on 6 December 2012

COVID-19 in patients with cutaneous immune-mediated diseases in The Netherlands: real-world observational data

scientific article published on 01 November 2020

Clinical and histopathological characterization of paradoxical head and neck erythema in patients with atopic dermatitis treated with dupilumab: a case series

scientific article published on 20 November 2019

Combinatorial Screening Identifies Novel Promiscuous Matrix Metalloproteinase Activities that Lead to Inhibition of the Therapeutic Target IL-13.

scientific article published on 3 November 2015

Current and Future Biomarkers in Atopic Dermatitis.

scientific article published on 28 October 2016

Cyclosporin A reduces CD4(+)CD25(+) regulatory T-cell numbers in patients with atopic dermatitis.

scientific article published on 19 September 2009

Cyclosporin A treatment is associated with increased serum immunoglobulin E levels in a subgroup of atopic dermatitis patients

scientific article published on 01 September 2007

Differential expression of genes involved in skin homing, proliferation, and apoptosis in CD4+ T cells of patients with atopic dermatitis.

scientific article

EASI p-EASI: Predicting disease severity in atopic dermatitis patients treated with dupilumab using a combination of serum biomarkers

scientific article published on 24 July 2020

EASI p-EASI: Utilizing a combination of serum biomarkers offers an objective measurement tool for disease severity in atopic dermatitis patients

scientific article published on 16 August 2017

EASI p-EASI: predicting disease severity in atopic dermatitis patients treated with Cyclosporin A

scientific article published on 16 December 2018

Effectiveness of dupilumab treatment in 95 patients with atopic dermatitis: daily practice data

scientific article published on 16 October 2019

Efficacy and safety of long-term treatment with cyclosporin A for atopic dermatitis

scientific article published on 01 January 2007

Epicutaneous application of house dust mite induces thymic stromal lymphopoietin in nonlesional skin of patients with atopic dermatitis.

scientific article

First experience with extended release tacrolimus in the treatment of adult patients with severe, difficult to treat atopic dermatitis: Clinical efficacy, safety and dose finding

scientific article published on 28 October 2015

Gene expression in CD4+ T-cells reflects heterogeneity in infant wheezing phenotypes

scientific article published on 09 July 2008

High-scatter T cells: a reliable biomarker for malignant T cells in cutaneous T-cell lymphoma.

scientific article

Immunoglobulin free light chains in adult atopic dermatitis patients do not correlate with disease severity.

scientific article published on 06 December 2016

Inflammation of the atherosclerotic cap and shoulder of the plaque is a common and locally observed feature in unruptured plaques of femoral and coronary arteries

scientific article published on 01 January 1999

Modulation of lymphocyte function in vivo via inhibition of calcineurin or purine synthesis in patients with atopic dermatitis

scientific article published on 24 May 2012

Moving toward endotypes in atopic dermatitis: Identification of patient clusters based on serum biomarker analysis

scientific article published on 12 April 2017

Multiplex platform technology and bioinformatics are essential for development of biomarkers in atopic dermatitis

scientific article published on 26 October 2016

PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation

scientific article published on 02 August 2018

Predicting therapy response to mycophenolic acid using UGT1A9 genotyping: towards personalized medicine in atopic dermatitis

scientific article published on 13 September 2016

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.

scientific article published on 7 December 2009

Risk of Non-melanoma Skin Cancer in Patients with Atopic Dermatitis Treated with Oral Immunosuppressive Drugs

scientific article published on 20 February 2017

Serum biomarker profiles suggest that atopic dermatitis is a systemic disease

scientific article published in February 2018

Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell- attracting chemokine (CTACK) levels in allergic diseases: TARC and CTACK are disease-specific markers for atopic dermatitis.

scientific article published in February 2004

The complex biology and contribution of Staphylococcus aureus in atopic dermatitis, current and future therapies.

scientific article published on 25 October 2016

Utility of serum thymus and activation-regulated chemokine as a biomarker for monitoring of atopic dermatitis severity

scientific article published on 04 September 2014