List of works - Abhinav Nath

A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles.

scientific article published on 08 January 2014

A flash in the pan: dissecting dynamic amyloid intermediates using fluorescence

scientific article

A functional role for intrinsic disorder in the tau-tubulin complex

scientific article

A membrane-bound antiparallel dimer of rat islet amyloid polypeptide

scientific article published on 22 September 2011

A theoretical validation of the substrate depletion approach to determining kinetic parameters

scientific article published on 2 June 2006

Adenylylation and catalytic properties of Mycobacterium tuberculosis glutamine synthetase expressed in Escherichia coli versus mycobacteria

scientific article published on 22 March 2004

Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.

scientific article

CYP26C1 Is a Hydroxylase of Multiple Active Retinoids and Interacts with Cellular Retinoic Acid Binding Proteins

scientific article published on 23 February 2018

Catalytic versus inhibitory promiscuity in cytochrome P450s: implications for evolution of new function

scientific article published on 11 March 2011

Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs

scientific article published on 25 April 2017

Diffusion of Soluble Aggregates of THIOMABs and Bispecific Antibodies in Serum

scientific article published on 10 April 2017

Expression and Functional Characterization of Breast Cancer-Associated Cytochrome P450 4Z1 in Saccharomyces cerevisiae.

scientific article published on 10 October 2017

Folded small molecule manipulation of islet amyloid polypeptide.

scientific article published on 12 June 2014

Functional promiscuity correlates with conformational heterogeneity in A-class glutathione S-transferases

scientific article published in Journal of Biological Chemistry

HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

scientific article published on 3 January 2018

In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation

scientific article published on 8 November 2016

Inferring Mechanistic Parameters from Amyloid Formation Kinetics by Approximate Bayesian Computation

scientific article

Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes

scientific article published in Journal of Biological Chemistry

Longitudinal characterisation of function and structure of Bietti crystalline dystrophy: report on a novel homozygous mutation in CYP4V2.

scientific article published on 11 July 2017

Molecular simulations of the fluctuating conformational dynamics of intrinsically disordered proteins ⬇️

scientific article published on October 12, 2012

Protein-induced photophysical changes to the amyloid indicator dye thioflavin T

scientific article

Quantifying and predicting the promiscuity and isoform specificity of small-molecule cytochrome P450 inhibitors

scientific article

Release of a disordered domain enhances HspB1 chaperone activity toward tau

scientific article published on 23 January 2020

Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity

scientific article published on 22 May 2015

The Rational Discovery of a Tau Aggregation Inhibitor

scientific article published on 05 October 2018

The conformational ensembles of α-synuclein and tau: combining single-molecule FRET and simulations

scientific article

Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance

scientific article published on 19 September 2018

Using a FRET Library with Multiple Probe Pairs To Drive Monte Carlo Simulations of α-Synuclein.

scientific article published in January 2018

List of works by Abhinav Nath

A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles.

A flash in the pan: dissecting dynamic amyloid intermediates using fluorescence

A functional role for intrinsic disorder in the tau-tubulin complex

A membrane-bound antiparallel dimer of rat islet amyloid polypeptide

A theoretical validation of the substrate depletion approach to determining kinetic parameters

Adenylylation and catalytic properties of Mycobacterium tuberculosis glutamine synthetase expressed in Escherichia coli versus mycobacteria

Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.

CYP26C1 Is a Hydroxylase of Multiple Active Retinoids and Interacts with Cellular Retinoic Acid Binding Proteins

Catalytic versus inhibitory promiscuity in cytochrome P450s: implications for evolution of new function

Differential Coupling of Binding, ATP Hydrolysis, and Transport of Fluorescent Probes with P-Glycoprotein in Lipid Nanodiscs

Diffusion of Soluble Aggregates of THIOMABs and Bispecific Antibodies in Serum

Expression and Functional Characterization of Breast Cancer-Associated Cytochrome P450 4Z1 in Saccharomyces cerevisiae.

Folded small molecule manipulation of islet amyloid polypeptide.

Functional promiscuity correlates with conformational heterogeneity in A-class glutathione S-transferases

HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation

In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation

Inferring Mechanistic Parameters from Amyloid Formation Kinetics by Approximate Bayesian Computation

Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes

Longitudinal characterisation of function and structure of Bietti crystalline dystrophy: report on a novel homozygous mutation in CYP4V2.

Molecular simulations of the fluctuating conformational dynamics of intrinsically disordered proteins ⬇️

Protein-induced photophysical changes to the amyloid indicator dye thioflavin T

Quantifying and predicting the promiscuity and isoform specificity of small-molecule cytochrome P450 inhibitors

Release of a disordered domain enhances HspB1 chaperone activity toward tau

Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity

The Rational Discovery of a Tau Aggregation Inhibitor

The conformational ensembles of α-synuclein and tau: combining single-molecule FRET and simulations

Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance

Using a FRET Library with Multiple Probe Pairs To Drive Monte Carlo Simulations of α-Synuclein.