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List of works by James H Morrissey

2013 scientific sessions Sol Sherry distinguished lecture in thrombosis: polyphosphate: a novel modulator of hemostasis and thrombosis.

scientific article published on 23 April 2015

A selective defect in tissue factor mRNA expression in monocytes from AIDS patients.

scientific article published in January 1990

A serine loop in tissue factor mediates substrate selectivity by the tissue factor - factor VIIa complex

scientific article published on 04 September 2020

A soluble tissue factor-annexin V chimeric protein has both procoagulant and anticoagulant properties

scientific article published on 29 September 2005

Ability of Polyphosphate and Nucleic Acids to Trigger Blood Clotting: Some Observations and Caveats.

scientific article published on 17 April 2018

Activated and Total Coagulation Factor VII, and Fibrinogen in Coronary Artery Disease ⬇️

scientific article published on January 1, 1998

Activated factor VII levels in patients with angiographically confirmed coronary artery disease

scientific article published on 01 July 1997

Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer ⬇️

scientific article published on February 1, 1998

Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.

scientific article published on 29 October 2014

Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA.

scientific article published on 29 December 2016

Artificial Dense Granules: A Procoagulant Liposomal Formulation Modeled after Platelet Polyphosphate Storage Pools.

scientific article published on 13 July 2016

Atomic view of calcium-induced clustering of phosphatidylserine in mixed lipid bilayers

scientific article

Bacterial polyphosphates interfere with the innate host defense to infection

scientific article published on 12 August 2020

Biochemical analysis of pleiotropy in Dictyostelium ⬇️

scientific article published on March 1, 1978

Blood clotting reactions on nanoscale phospholipid bilayers

scientific article

CD Antigens 2001

CD Antigens 2001

CD antigens 2002

scientific article published on 01 May 2002

Calcium-Induced Lipid Nanocluster Structures: Sculpturing of the Plasma Membrane

scientific article published on 04 December 2018

Clotting activity of polyphosphate-functionalized silica nanoparticles.

scientific article published on 4 February 2015

Coagulation factor VIIa binds to herpes simplex virus 1-encoded glycoprotein C forming a factor X-enhanced tenase complex oriented on membranes

scientific article published on 07 March 2020

Colloidal Confinement of Polyphosphate on Gold Nanoparticles Robustly Activates the Contact Pathway of Blood Coagulation.

scientific article published on December 2015

DNA ladders can be used to size polyphosphate resolved by polyacrylamide gel electrophoresis.

scientific article published on 26 July 2018

Deeper understanding of carboxylase

scientific article published on 01 April 2016

Design of Polyphosphate Inhibitors: A Molecular Dynamics Investigation on Polyethylene Glycol-Linked Cationic Binding Groups.

scientific article published on 14 March 2018

Differential Roles for the Coagulation Factors XI and XII in Regulating the Physical Biology of Fibrin.

scientific article published on 8 December 2016

Differentiation-related death of an established keratinocyte line in suspension culture.

scientific article published on December 1978

Diversification of polyphosphate end-labeling via bridging molecules

scientific article published on 21 August 2020

Down-regulation of monocyte tissue factor mediated by tissue factor pathway inhibitor and the low density lipoprotein receptor-related protein.

scientific article published on February 1999

Effect of soluble tissue factor on the kinetic mechanism of factor VIIa: enhancement of p-guanidinobenzoate substrate hydrolysis

scientific article published on 01 June 1996

Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies

scientific article published on 22 March 2018

Experimental Protein Structure Verification by Scoring with a Single, Unassigned NMR Spectrum.

scientific article

Expression and purification of a soluble tissue factor fusion protein with an epitope for an unusual calcium-dependent antibody

scientific article published on 01 December 1992

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4 ⬇️

scientific article published on June 14, 2011

FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men

scientific article

FXIa and platelet polyphosphate as therapeutic targets during human blood clotting on collagen/tissue factor surfaces under flow

scientific article

Factor VII and protein C are phosphatidic acid-binding proteins.

scientific article published on 07 August 2013

Factor XI anion-binding sites are required for productive interactions with polyphosphate.

scientific article

Factor XII Activation Promotes Platelet Consumption in the Presence of Bacterial-Type Long-Chain Polyphosphate In Vitro and In Vivo

scientific article published on 01 August 2018

Factor XII inhibition reduces thrombus formation in a primate thrombosis model

scientific article published on 09 January 2014

Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates.

scientific article published on July 2013

Gender-related differences in thrombogenic factors predicting recurrent cardiac events in patients after acute myocardial infarction. The THROMBO Investigators

scientific article published on 01 June 2000

Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

scientific article published on November 2010

Heparin is procoagulant in the absence of antithrombin.

scientific article published in July 2008

High-Resolution NMR Studies of Human Tissue Factor

scientific article

How it all starts: Initiation of the clotting cascade.

scientific article published on 28 May 2015

Immobilized transition metal ions stimulate contact activation and drive factor XII‐mediated coagulation ⬇️

scientific article published on October 1, 2012

Influence of fatty acid chain length and cis/trans isomerization on postprandial lipemia and factor VII in healthy subjects (postprandial lipids and factor VII)

scientific article published on 01 April 2000

Influence of membrane composition on the enhancement of factor VIIa/tissue factor activity by magnesium ions.

scientific article published on 28 November 2013

Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation ⬇️

scientific article published on September 11, 2012

Inorganic polyphosphate interacts with nucleolar and glycosomal proteins in trypanosomatids

scientific article published on 18 October 2018

Lipid specificity of the membrane binding domain of coagulation factor X.

scientific article published on 7 August 2017

Localization of Short-Chain Polyphosphate Enhances its Ability to Clot Flowing Blood Plasma.

scientific article

Low‐carb tissue factor? ⬇️

scientific article published on August 1, 2011

Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade.

scientific article published in July 1987

Molecular determinants of phospholipid synergy in blood clotting

scientific article

Monoclonal antibodies specific for stalk differentiation in Dictyostelium discoideum

scientific article published on 01 August 1984

Monoclonal antibody analysis of purified and cell-associated tissue factor.

scientific article

Multiplexed silicon photonic sensor arrays enable facile characterization of coagulation protein binding to nanodiscs with variable lipid content.

scientific article published on 11 August 2017

Nanoscale studies of protein-membrane interactions in blood clotting.

scientific article published on July 2011

Needs and challenges among physicians and researchers in thrombosis and hemostasis: Results from an international study

scientific article published on 28 June 2019

Nomenclature of factor XI and the contact system

scientific article published on 13 August 2019

Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis.

scientific article

One inositol ring to rule thrombosis

scientific article published on 01 August 2013

Pattern formation in Dictyostelium discoideum: an analysis of mutants altered in cell proportioning

scientific article published on 01 April 1981

Phosphatidylethanolamine augments factor VIIa-tissue factor activity: enhancement of sensitivity to phosphatidylserine

scientific article published on 01 October 1995

Phospholipid composition controls thromboplastin sensitivity to individual clotting factors.

scientific article

Phosphoramidate end labeling of inorganic polyphosphates: facile manipulation of polyphosphate for investigating and modulating its biological activities

scientific article

Platelet polyphosphate induces fibroblast chemotaxis and myofibroblast differentiation

scientific article published on 18 August 2020

Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo

scientific article

Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI.

scientific article

Polyphosphate accelerates factor V activation by factor XIa.

scientific article

Polyphosphate and RNA Differentially Modulate the Contact Pathway of Blood Clotting.

scientific article published on 22 December 2016

Polyphosphate and omptins: novel bacterial procoagulant agents

scientific article

Polyphosphate as modulator of hemostasis, thrombosis, and inflammation

scientific article published in June 2015

Polyphosphate binds with high affinity to exosite II of thrombin.

scientific article published on 11 December 2009

Polyphosphate enhances fibrin clot structure

scientific article published on 10 June 2008

Polyphosphate exerts differential effects on blood clotting, depending on polymer size.

scientific article

Polyphosphate in thrombosis, hemostasis, and inflammation

scientific article published on 15 November 2018

Polyphosphate is a cofactor for the activation of factor XI by thrombin

scientific article published on 5 October 2011

Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor.

scientific article published on 23 June 2016

Polyphosphate modulates blood coagulation and fibrinolysis.

scientific article

Polyphosphate multi‐tasks ⬇️

scientific article published on November 1, 2012

Polyphosphate suppresses complement via the terminal pathway

scientific article published on 13 December 2013

Polyphosphate, Zn2+ and high molecular weight kininogen modulate individual reactions of the contact pathway of blood clotting

scientific article published on 18 September 2019

Polyphosphate, platelets, and coagulation

scientific article published on May 2015

Polyphosphate: a link between platelets, coagulation and inflammation ⬇️

scientific article published on April 5, 2012

Polyphosphate: a new player in the field of hemostasis

scientific article published on September 2014

Protein-membrane interactions: blood clotting on nanoscale bilayers

scientific article

Protein-phospholipid interactions in blood clotting

scientific article published on 04 February 2010

Proteolysis of Blood Coagulation Factor VIII by the Factor VIIa−Tissue Factor Complex: Generation of an Inactive Factor VIII Cofactor†

scientific article published on 01 May 1999

Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19

scientific article published on 02 November 2020

Raising the active site of factor VIIa above the membrane surface reduces its procoagulant activity but not factor VII autoactivation

scientific article published on 11 July 2006

Rapid and efficient incorporation of tissue factor into liposomes.

scientific article

Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia.

scientific article published in March 2007

Relationship between markers of activated coagulation, their correlation with inflammation, and association with coronary heart disease (NPHSII).

scientific article published on 29 October 2007

Relationships of plasma factor VIIa-antithrombin complexes to manifest and future cardiovascular disease

scientific article published on 16 September 2011

Resolution of acid-soluble protein component of yolk platelets from Xenopus laevis eggs on polyacrylamide gels ⬇️

scientific article published on July 1, 1974

Resolution of monomeric and heterodimeric forms of tissue factor, the high-affinity cellular receptor for factor VII ⬇️

scientific article published on May 15, 1988

Restoring full biological activity to the isolated ectodomain of an integral membrane protein

scientific article published on March 2006

Silica particles contribute to the procoagulant activity of DNA and polyphosphate isolated using commercial kits.

scientific article published on 22 May 2017

Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced uniform sensitivity ⬇️

scientific article (publication date: November 1981)

Size-controlled synthesis of granular polyphosphate nanoparticles at physiologic salt concentrations for blood clotting

scientific article published on 7 October 2014

Structure-Function Relationship of the Interaction between Tissue Factor and Factor VIIa.

scientific article published on 26 September 2015

Substrate recognition by tissue factor-factor VIIa. Evidence for interaction of residues Lys165 and Lys166 of tissue factor with the 4-carboxyglutamate-rich domain of factor X

scientific article published on 01 September 1996

Synthesis and evaluation of chromogenic and fluorogenic substrates for high-throughput detection of enzymes that hydrolyze inorganic polyphosphate.

scientific article

Taking the brakes off? ⬇️

scientific article published on April 14, 2011

Targeting factor XI to prevent thrombosis

scientific article published on July 2013

The Local Phospholipid Environment Modulates the Activation of Blood Clotting

scientific article published in Journal of Biological Chemistry

The cofactor function of the N-terminal domain of tissue factor.

scientific article published on 13 July 2004

The location of the active site of blood coagulation factor VIIa above the membrane surface and its reorientation upon association with tissue factor. A fluorescence energy transfer study

scientific article published on 01 November 1996

The many domains of TFPI.

scientific article

The timing of cell-type-specific differentiation in Dictyostelium discoideum.

scientific article published in June 1984

Tissue Factor Expression in Mesothelial Cells: Induction BothIn VivoandIn Vitro ⬇️

scientific article published on 01 August 1997

Tissue Factor Residues That Modulate Magnesium-Dependent Rate Enhancements of the Tissue Factor/Factor VIIa Complex.

scientific article published on 27 July 2015

Tissue factor alters the pK(a) values of catalytically important factor VIIa residues.

scientific article published in March 2002

Tissue factor as a proinflammatory agent

scientific article

Tissue factor positions and maintains the factor VIIa active site far above the membrane surface even in the absence of the factor VIIa Gla domain. A fluorescence resonance energy transfer study

scientific article published on 01 November 1997

Tissue factor residues that putatively interact with membrane phospholipids

scientific article

Tissue factor/factor VIIa complex: role of the membrane surface

scientific article

Traces of factor VIIa modulate thromboplastin sensitivity to factors V, VII, X, and prothrombin

scientific article published on 01 July 2006

Two signals to shape a slime mould

scientific article published on 01 May 1983

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