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List of works by Chris Ward

'To measure is to know' (Lord Kelvin).

scientific article published on 17 November 2014

A call for standardization of antireflux surgery in the lung transplantation population.

scientific article published on April 2009

A controlled trial of nebulized aminoglycoside and oral flucloxacillin versus placebo in the outpatient management of children with cystic fibrosis

scientific article published on 01 October 1987

A descriptive study of small airway reticular basement membrane thickening in clinically stable lung transplant recipients

scientific article published on 01 May 2005

A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk

scientific article published on 30 June 2018

A randomised controlled trial of azithromycin therapy in bronchiolitis obliterans syndrome (BOS) post lung transplantation

scientific article published on 24 February 2015

A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study

scientific article

Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD).

scientific article published on 17 October 2017

Addition of inhaled corticosteroids to systemic immunosuppression after lung transplantation: a double-blind, placebo-controlled trial.

scientific article published in June 2002

Airway cell and cytokine changes in early asthma deterioration after inhaled corticosteroid reduction

scientific article published on 01 August 2007

Airway epithelial cell senescence in the lung allograft

scientific article published on 01 July 2008

Airway epithelial cells as guardians of immune homeostasis?

scientific article published on 01 November 2009

Airway inflammation and inhaled corticosteroids in COPD.

scientific article published on 15 June 2017

Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets.

scientific article published on 30 December 2015

Airway vascular changes in lung allograft recipients

scientific article published on 01 March 1999

Airway versus transbronchial biopsy and BAL in lung transplant recipients: different but complementary

scientific article published on 01 December 1997

Albumin is not suitable as a marker of bronchoalveolar lavage dilution in interstitial lung disease

scientific article published on 01 September 1997

Allergen-induced airway reactions in atopic asthmatics correlate with allergen-specific IL-5 response by BAL cells

scientific article published on 01 March 1997

Alveolar macrophages from atopic asthmatics, but not atopic nonasthmatics, enhance interleukin-5 production by CD4+ T cells

scientific article published on 01 April 1998

An antiinflammatory effect of salmeterol, a long-acting beta(2) agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma

scientific article published on 01 November 1999

Anatomical distribution of bronchoalveolar lavage fluid as assessed by digital subtraction radiography.

scientific article published on August 1987

Angiogenesis: a potentially critical part of remodelling in chronic airway diseases?

scientific article published on 15 February 2008

Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life.

scientific article published on 20 July 2011

Antimicrobial peptides in lung transplant recipients with bronchiolitis obliterans syndrome

scientific article published on 28 May 2008

Are the enzymatic methods currently being used to measure bronchoalveolar lavage bile salt levels fit for purpose?

scientific article published on 04 February 2013

Aspiration and allograft injury secondary to gastroesophageal reflux occur in the immediate post-lung transplantation period (prospective clinical trial)

article

Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPD

scientific article

Assessment of pulmonary macrophage and neutrophil function in sequential bronchoalveolar lavage aspirates in sarcoidosis.

scientific article

Bile acid aspiration in people with cystic fibrosis before and after lung transplantation.

scientific article published on 22 October 2015

Bile acids are present in the lower airways of people with cystic fibrosis.

scientific article

Bile acids: a potential role in the pathogenesis of pharyngeal malignancy.

scientific article

Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells.

scientific article published on 21 January 2009

Bronchial hyperresponsiveness in lung transplant recipients: lack of correlation with airway inflammation

scientific article published on June 1997

Bronchoalveolar Lavage (BAL) : Critical Evaluation of Techniques.

scientific article

Bronchoalveolar lavage cellular profiles in lung transplantation: the effect of inhaled corticosteroids

scientific article published on 01 January 2000

Bronchoalveolar lavage fluid urea as a measure of pulmonary permeability in healthy smokers

scientific article published on 01 February 2000

Bronchoalveolar lavage in asthma research.

scientific article published on December 1996

Bronchoalveolar lavage macrophage and lymphocyte phenotypes in lung transplant recipients

scientific article published on 01 October 2001

Bronchoalveolar lavage(BAL) neutrophilia in lung transplant recipients(LTR): infection and bronchiolitis obliterans syndrome(BOS), the chicken or the egg?

scientific article published on 01 February 2001

CK2 is a key regulator of SLC4A2-mediated Cl-/HCO3- exchange in human airway epithelia.

scientific article published on 28 April 2017

Can cells other than Th17 lymphocytes be important sources of IL-17 in the lungs?

scientific article published on 15 March 2011

Ceramide and cystic fibrosis lung disease

scientific article published on 01 January 2011

Ceramide is increased in the lower airway epithelium of people with advanced cystic fibrosis lung disease

scientific article published on 15 April 2010

Clonally Related Viable Nontuberculous Mycobacteria in Gastric Juice and Sputum in People with Cystic Fibrosis

scientific article published on 10 June 2020

Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study.

scientific article

Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2

scientific article published on 07 December 2021

Differential regulation of allergen-specific T(H2)- but not T(H1)-type responses by alveolar macrophages in atopic asthma

scientific article published on 01 September 1998

Effect of high dose inhaled fluticasone propionate on airway inflammation in asthma.

scientific article published in July 1995

Effects of bile acids on human airway epithelial cells: implications for aerodigestive diseases.

scientific article

Effects of long-term low-dose azithromycin in patients with non-CF bronchiectasis.

scientific article published on 23 July 2008

Efficacy of nebulised colomycin in patients with non-cystic fibrosis bronchiectasis colonised with Pseudomonas aeruginosa

scientific article published on 01 June 2010

Elevated paracellular glucose flux across cystic fibrosis airway epithelial monolayers is an important factor for Pseudomonas aeruginosa growth

scientific article

Endobronchial biopsy and bronchoalveolar lavage in stable lung transplant recipients and chronic rejection

scientific article published on 01 July 1998

Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease.

scientific article published on 14 February 2017

Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction

scientific article

Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation.

scientific article

Epithelial-Mesenchymal Transition: A Necessary New Therapeutic Target in Chronic Obstructive Pulmonary Disease?

scientific article published in August 2017

Epithelial-mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease.

scientific article

Establishment of an immortalized human subglottic epithelial cell line

scientific article published on 08 January 2019

Evaluation of albumin as a reference marker of dilution in bronchoalveolar lavage fluid from asthmatic and control subjects.

scientific article

Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary disease

scientific article

Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients

scientific article published on 9 February 2018

Exhaled nitric oxide continues to reflect airway hyperresponsiveness and disease activity in inhaled corticosteroid-treated adult asthmatic patients

scientific article published in December 2003

Features of bronchoalveolar lavage (BAL) in lung transplant recipients (LTR) who later develop bronchiolitis obliterans syndrome (BOS)

scientific article published on 01 February 2001

From gastric aspiration to airway inflammation

scientific article published on 01 June 2010

Hiatal hernias are correlated with increased severity of non-cystic fibrosis bronchiectasis.

scientific article published on 14 April 2015

Hospitalization Outcomes for COVID-19 in Patients with Interstitial Lung Disease; a Potential Role for Aerodigestive Pathophysiology?

scientific article published on 20 November 2020

Hypercapnia modulates cAMP signalling and cystic fibrosis transmembrane conductance regulator-dependent anion and fluid secretion in airway epithelia.

scientific article published on 17 November 2015

Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H+ secretion

scientific article

Hypertonic saline challenge predicts early onset bronchiolitis obliterans syndrome post-lung transplantation

scientific article published on 01 February 2001

IL-22 exacerbates weight loss in a murine model of chronic pulmonary Pseudomonas aeruginosa infection

scientific article published on 30 June 2016

IL-5 production by bronchoalveolar lavage and peripheral blood mononuclear cells in asthma and atopy

scientific article published on 01 March 1997

Immunopathological changes in the airways of stable lung transplant recipients.

scientific article published on April 1997

Importance of epithelial mesenchymal transition (EMT) in COPD and asthma.

scientific article published on 19 May 2014

Increased soluble CD14 in bronchoalveolar lavage fluid of stable lung transplant recipients

scientific article published on 01 March 2002

Increased vascular endothelial growth factor and receptors: relationship to angiogenesis in asthma

scientific article published on 09 March 2006

Infection and remodelling: a 21st century model of bronchiectasis?

scientific article published on 01 October 2011

Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD.

scientific article published on 22 September 2016

Innate immune activation in neutrophilic asthma

scientific article published on 01 January 2008

Inter-relationships between airway inflammation, reticular basement membrane thickening and bronchial hyper-reactivity to methacholine in asthma; a systematic bronchoalveolar lavage and airway biopsy analysis.

scientific article published in December 2005

Interleukin-17 and cystic fibrosis lung disease

scientific article published on 01 January 2012

Intrasubject variability in airway inflammation in biopsies in mild to moderate stable asthma

scientific article published on 01 March 1996

Ivacaftor and symptoms of extra-oesophageal reflux in patients with cystic fibrosis and G551D mutation

scientific article published on 27 July 2016

Lack of association between KIR and HLA-C type and susceptibility to idiopathic bronchiectasis

scientific article published on 18 June 2014

Laryngeal candidiasis: Our experience from sixty biopsy specimens

scientific article published on 20 November 2017

Longitudinal changes in gastro-oesophageal reflux from 3 months to 6 months after lung transplantation

scientific article published on 01 November 2009

Lung transplantation, gastroesophageal reflux, and fundoplication.

scientific article published on February 2010

Lymphocyte subsets in bronchoalveolar lavage fluid obtained from stable asthmatics, and their correlations with bronchial responsiveness

scientific article published on 01 March 1989

Macrolide antibiotics and the airway: antibiotic or non-antibiotic effects?

scientific article published on March 2010

Mechanism of the inhibitory effect of trifluoperazine on isoprenaline-evoked amylase secretion from isolated rat parotid glands

scientific article published on 01 December 1986

Mechanistic differences between phenotypes of chronic lung allograft dysfunction after lung transplantation

scientific article

Microbiological profiles of sputum and gastric juice aspirates in Cystic Fibrosis patients

scientific article published on June 2016

Modulatory effects of alveolar macrophages on CD4+ T-cell IL-5 responses correlate with IL-1beta, IL-6, and IL-12 production

scientific article published on 01 July 1999

Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts.

scientific article published on 11 August 2016

Non-cystic fibrosis bronchiectasis

scientific article published on 30 May 2013

Nontuberculous mycobacteria in gastrostomy fed patients with cystic fibrosis.

scientific article

Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma.

scientific article

Pepsin, a biomarker of gastric aspiration in lung allografts: a putative association with rejection.

scientific article published on 5 April 2007

Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients.

scientific article published on 21 June 2005

Phenotyping adults with non-cystic fibrosis bronchiectasis: a prospective observational cohort study.

scientific article published on 11 May 2013

Pleuropulmonary abnormalities in primary Sjögren's syndrome

scientific article published on 01 May 1993

Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo.

scientific article

Post-lung transplant bronchiolitis obliterans syndrome (BOS) is characterized by increased exhaled nitric oxide levels and epithelial inducible nitric oxide synthase

scientific article published on 01 December 2000

Preliminary findings of quorum signal molecules in clinically stable lung allograft recipients.

scientific article published in May 2003

Primary airway epithelial cell culture from lung transplant recipients.

scientific article published on December 2005

Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD.

scientific article

Pseudomonas aeruginosa accentuates epithelial-to-mesenchymal transition in the airway ⬇️

scientific article published on September 16, 2010

Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease

scientific article published on 25 November 2010

Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis

scientific article published on 04 January 2019

Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells

scientific article published on 13 June 2019

Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis

scientific article published on 22 June 2020

Reduced airway distensibility, fixed airflow limitation, and airway wall remodeling in asthma

scientific article published on 01 November 2001

Reflux in idiopathic pulmonary fibrosis: treatment informed by an integrated approach

scientific article published on 01 October 2018

Regarding epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

scientific article published on 10 October 2019

Response

Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease.

scientific article published on 12 July 2010

Reticular basement membrane thickening in airways of lung transplant recipients is not affected by inhaled corticosteroids.

scientific article published in December 2004

Risk factors for lung disease progression in children with cystic fibrosis

article

Scar collagen deposition in the airways of allografts of lung transplant recipients

scientific article published on 01 June 1997

Seasonal comparison of cytokine profiles in atopic asthmatics and atopic non-asthmatics

scientific article published on 01 December 1996

Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients.

scientific article published on 18 January 2008

Susceptibility to exacerbation in COPD

scientific article published on 01 December 2010

TNFα from classically activated macrophages accentuates epithelial to mesenchymal transition in obliterative bronchiolitis.

scientific article published on 17 January 2013

Telomere Dysfunction and Senescence-associated Pathways in Bronchiectasis

scientific article published on April 2016

The Potential Role of Aspiration in the Asthmatic Airway

scientific article published on 11 March 2017

The Potential Role of Bile Acids in Acquired Laryngotracheal Stenosis

scientific article published on 5 February 2018

The effect of filtration on absolute and differential cell counts in fluid obtained at bronchoalveolar lavage

scientific article published on 01 March 1989

The origin of water and urea sampled at bronchoalveolar lavage in asthmatic and control subjects

scientific article published on August 1, 1992

The phosphodiesterase type IV inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells in lung transplantation patients.

scientific article

The potential role of microRNAs in lung allograft rejection.

scientific article published on 31 March 2016

The presence of Aspergillus fumigatus in asthmatic airways is not clearly related to clinical disease severity

scientific article published on 12 October 2019

The relative contribution of bronchoalveolar macrophages and neutrophils to lucigenin- and luminol-amplified chemiluminescence

scientific article published on 01 October 1990

Transforming growth factor (TGF) β1 and Smad signalling pathways: A likely key to EMT-associated COPD pathogenesis

scientific article

Vascular remodelling in asthma

scientific article published on February 2008

β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction.

scientific article published on 7 September 2017

β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections

scientific article

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