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List of works by Fabrice Chimienti

A game changer for bipolar disorder diagnosis using RNA editing-based biomarkers

scientific article published on 04 May 2022

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

scientific article published on 28 April 2010

Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study

scientific article

Effects of high-fat diet feeding on Znt8-null mice: differences between β-cell and global knockout of Znt8

scientific article published on February 14, 2012

Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitro

scientific article

Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells

scientific article

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

scientific article

Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda

scientific article

In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression

scientific article published on 23 May 2004

In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

scientific article

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

scientific article published on 18 August 2009

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants

scientific article

Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.

scientific article published on 4 February 2008

Modeling human pancreatic beta cell dedifferentiation

scientific article published on 8 February 2018

Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4.

scientific article

Phosphodiesterase 8A to discriminate in blood samples depressed patients and suicide attempters from healthy controls based on A-to-I RNA editing modifications

scientific article published on 30 April 2021

Prion protein protects against zinc-mediated cytotoxicity by modifying intracellular exchangeable zinc and inducing metallothionein expression

scientific article

Regulation of glucagon secretion by zinc: lessons from the β cell-specific Znt8 knockout mouse model.

scientific article published on October 2011

Resveratrol enhances UVA-induced DNA damage in HaCaT human keratinocytes.

scientific article

Role of cellular zinc in programmed cell death: temporal relationship between zinc depletion, activation of caspases, and cleavage of Sp family transcription factors.

scientific article published in July 2001

SLC30A8 mutations in type 2 diabetes

scientific article published on 07 October 2014

Tolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cells

scientific article published on 4 February 2013

Zinc homeostasis-regulating proteins: new drug targets for triggering cell fate.

scientific article

Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?

scientific journal article

Zinc transporters and their role in the pancreatic β-cell

scientific article

Zinc, pancreatic islet cell function and diabetes: new insights into an old story

scientific article published on 03 January 2013

ZnT-8, a pancreatic beta-cell-specific zinc transporter

scientific article