List of works - Björn E Clausen

1,25-dihydroxyvitamin D exerts similar immunosuppressive effects as UVR but is dispensable for local UVR-induced immunosuppression.

scientific article published on 2 August 2012

Aldara-induced psoriasis-like skin inflammation: isolation and characterization of cutaneous dendritic cells and innate lymphocytes.

scientific article published in January 2014

Alveolar epithelial cells orchestrate DC function in murine viral pneumonia

scientific article published on 10 September 2012

An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation.

scientific article

Analysis of immunoglobulin gamma heavy chains from rheumatoid arthritis synovium. Evidence of antigen-driven selection

scientific article published on 01 September 1995

Arsenic mobilizes Langerhans cell migration and induces Th1 response in epicutaneous protein sensitization via CCL21: a plausible cause of decreased Langerhans cells in arsenic-induced intraepithelial carcinoma

scientific article published on 01 February 2012

Aryl Hydrocarbon Receptor in Keratinocytes Is Essential for Murine Skin Barrier Integrity.

scientific article

Aryl hydrocarbon receptor is critical for homeostasis of invariant gammadelta T cells in the murine epidermis.

scientific article

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups

scientific article published on 2 February 2015

Beta-catenin signaling drives differentiation and proinflammatory function of IRF8-dependent dendritic cells

scientific article

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

scientific article

Clearance of influenza virus from the lung depends on migratory langerin+CD11b- but not plasmacytoid dendritic cells

scientific article published on July 2008

Clonally-related immunoglobulin VH domains and nonrandom use of DH gene segments in rheumatoid arthritis synovium

scientific article

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

scientific article

Conditional deletion of TGF-βR1 using Langerin-Cre mice results in Langerhans cell deficiency and reduced contact hypersensitivity

scientific article published on 12 October 2011

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

scientific article published in August 1999

Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes

scientific article

Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis

scientific article published on 20 November 2015

Dendritic cells as gatekeepers of tolerance.

scientific article

Dendritic cells in distinct oral mucosal tissues engage different mechanisms to prime CD8+ T cells

scientific article published on 15 December 2010

Dermal CD207 negative migratory dendritic cells are fully competent to prime protective, skin homing CTL responses

article

Dermal dendritic cells, but not Langerhans cells, are critical in murine single epicutaneous sensitization

scientific article published on 08 December 2014

Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation

scientific article published on 01 October 2005

Directly transfected langerin+ dermal dendritic cells potentiate CD8+ T cell responses following intradermal plasmid DNA immunization

scientific article published on 16 August 2010

Dual therapeutic efficacy of vinblastine as a unique chemotherapeutic agent capable of inducing dendritic cell maturation

scientific article

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

scientific article

Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN

scientific journal article

Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses

scientific article

Functional redundancy of Langerhans cells and Langerin+ dermal dendritic cells in contact hypersensitivity

scientific article

Gradual development of psoriatic skin lesions by constitutive low-level expression of IL-17A.

scientific article published on 26 November 2015

HIF-1alpha is essential for myeloid cell-mediated inflammation

scientific article (publication date: 7 March 2003)

Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.

scientific article published in November 2003

IL-10 control of CD11c+ myeloid cells is essential to maintain immune homeostasis in the small and large intestine.

scientific article published on 24 March 2016

IL-10 control of dendritic cells in the skin.

scientific article published on March 2013

IL-10 controls dendritic cell-induced T-cell reactivation in the skin to limit contact hypersensitivity

scientific article published on 5 October 2011

IL-10 signaling in dendritic cells attenuates anti-Leishmania major immunity without affecting protective memory responses

scientific article published on 22 June 2015

IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence.

scientific article

IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively

scientific article

ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells.

scientific article

Immunology. Beta-catenin balances immunity.

scientific article

In cutaneous leishmaniasis, induction of retinoic acid in skin-derived Langerhans cells is not sufficient for induction of parasite persistence-mediating regulatory T cells.

scientific article published on 17 June 2017

In vivo reprogramming of UV radiation-induced regulatory T-cell migration to inhibit the elicitation of contact hypersensitivity

scientific article published on 16 July 2011

Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity

scientific article

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

scientific article

Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells.

scientific article published on 20 December 2017

Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome.

scientific article published on 5 December 2011

Langerhans cells and NK cells cooperate in the inhibition of chemical skin carcinogenesis.

scientific article published on 18 November 2016

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.

scientific article published on March 2010

Langerhans cells are negative regulators of the anti-Leishmania response. ⬇️

scientific article

Langerhans cells are required for efficient presentation of topically applied hapten to T cells

scientific article published on 01 November 2007

Langerhans cells down-regulate inflammation-driven alveolar bone loss.

scientific article

Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice.

scientific article published on 10 June 2013

Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection.

scientific article published on 21 May 2018

Leishmaniasis, contact hypersensitivity and graft-versus-host disease: understanding the role of dendritic cell subsets in balancing skin immunity and tolerance

scientific article published on 01 August 2010

Limited capacity for tolerization of CD4+ T cells specific for a pancreatic beta cell neo-antigen.

scientific article published on June 1995

Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy

scientific article published on 19 April 2007

Monitoring Skin Dendritic Cells in Steady State and Inflammation by Immunofluorescence Microscopy and Flow Cytometry

scientific article published on January 2017

Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation.

scientific article published on 16 December 2016

Mouse lysozyme-M knockout mice reveal how the self-determinant hierarchy shapes the T cell repertoire against this circulating self antigen in wild-type mice

scientific article published on 01 August 2004

Multicolor fate mapping of Langerhans cell homeostasis

scientific article published on 12 August 2013

Multifaceted contributions of epidermal langerhans cells to cutaneous carcinogenesis

scientific article published on 01 May 2015

Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions

scholarly article

Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice

scientific article

Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells

scientific article

Production of Extracellular Adenosine by CD73 Dendritic Cells is Crucial for Induction of Tolerance in Contact Hypersensitivity Reactions

scientific article published on 28 October 2018

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.

scientific article

Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.

scientific article published on June 2003

Reproducibility Issues: Avoiding Pitfalls in Animal Inflammation Models.

scientific article

Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice.

scientific article published in February 1998

SOCS3 negatively regulates IL-6 signaling in vivo

scientific article

Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming

scientific article published on 13 January 2014

Selective AhR knockout in langerin-expressing cells abates Langerhans cells and polarizes Th2/Tr1 in epicutaneous protein sensitization

scientific article published on 27 May 2020

Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation.

scientific article published on 17 January 2018

Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor.

scientific article published on 14 July 2015

Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.

scientific article

Surmounting limited gene delivery into primary immune cell populations: Efficient cell type-specific adenoviral transduction by CAR.

scientific article published on 12 May 2015

TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity.

scientific article

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.

scientific article published on 20 September 2017

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity

scientific article

The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells

scientific article

The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis

scientific article

The lung vascular filter as a site of immune induction for T cell responses to large embolic antigen

scientific article

Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity

scientific article published on 13 May 2014

β-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8+ T cells through regulation of IL-10.

scientific article

β-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8⁺ T cells

scientific article published on 10 September 2013

List of works by Björn E Clausen

1,25-dihydroxyvitamin D exerts similar immunosuppressive effects as UVR but is dispensable for local UVR-induced immunosuppression.

Aldara-induced psoriasis-like skin inflammation: isolation and characterization of cutaneous dendritic cells and innate lymphocytes.

Alveolar epithelial cells orchestrate DC function in murine viral pneumonia

An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation.

Analysis of immunoglobulin gamma heavy chains from rheumatoid arthritis synovium. Evidence of antigen-driven selection

Arsenic mobilizes Langerhans cell migration and induces Th1 response in epicutaneous protein sensitization via CCL21: a plausible cause of decreased Langerhans cells in arsenic-induced intraepithelial carcinoma

Aryl Hydrocarbon Receptor in Keratinocytes Is Essential for Murine Skin Barrier Integrity.

Aryl hydrocarbon receptor is critical for homeostasis of invariant gammadelta T cells in the murine epidermis.

BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups

Beta-catenin signaling drives differentiation and proinflammatory function of IRF8-dependent dendritic cells

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine

Clearance of influenza virus from the lung depends on migratory langerin+CD11b- but not plasmacytoid dendritic cells

Clonally-related immunoglobulin VH domains and nonrandom use of DH gene segments in rheumatoid arthritis synovium

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

Conditional deletion of TGF-βR1 using Langerin-Cre mice results in Langerhans cell deficiency and reduced contact hypersensitivity

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes

Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis

Dendritic cells as gatekeepers of tolerance.

Dendritic cells in distinct oral mucosal tissues engage different mechanisms to prime CD8+ T cells

Dermal CD207 negative migratory dendritic cells are fully competent to prime protective, skin homing CTL responses

Dermal dendritic cells, but not Langerhans cells, are critical in murine single epicutaneous sensitization

Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation

Directly transfected langerin+ dermal dendritic cells potentiate CD8+ T cell responses following intradermal plasmid DNA immunization

Dual therapeutic efficacy of vinblastine as a unique chemotherapeutic agent capable of inducing dendritic cell maturation

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN

Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses

Functional redundancy of Langerhans cells and Langerin+ dermal dendritic cells in contact hypersensitivity

Gradual development of psoriatic skin lesions by constitutive low-level expression of IL-17A.

HIF-1alpha is essential for myeloid cell-mediated inflammation

Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.

IL-10 control of CD11c+ myeloid cells is essential to maintain immune homeostasis in the small and large intestine.

IL-10 control of dendritic cells in the skin.

IL-10 controls dendritic cell-induced T-cell reactivation in the skin to limit contact hypersensitivity

IL-10 signaling in dendritic cells attenuates anti-Leishmania major immunity without affecting protective memory responses

IL-10 suppression of NK/DC crosstalk leads to poor priming of MCMV-specific CD4 T cells and prolonged MCMV persistence.

IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively

ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells.

Immunology. Beta-catenin balances immunity.

In cutaneous leishmaniasis, induction of retinoic acid in skin-derived Langerhans cells is not sufficient for induction of parasite persistence-mediating regulatory T cells.

In vivo reprogramming of UV radiation-induced regulatory T-cell migration to inhibit the elicitation of contact hypersensitivity

Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells.

Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome.

Langerhans cells and NK cells cooperate in the inhibition of chemical skin carcinogenesis.

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin.

Langerhans cells are negative regulators of the anti-Leishmania response. ⬇️

Langerhans cells are required for efficient presentation of topically applied hapten to T cells

Langerhans cells down-regulate inflammation-driven alveolar bone loss.

Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice.

Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection.

Leishmaniasis, contact hypersensitivity and graft-versus-host disease: understanding the role of dendritic cell subsets in balancing skin immunity and tolerance

Limited capacity for tolerization of CD4+ T cells specific for a pancreatic beta cell neo-antigen.

Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy

Monitoring Skin Dendritic Cells in Steady State and Inflammation by Immunofluorescence Microscopy and Flow Cytometry

Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation.

Mouse lysozyme-M knockout mice reveal how the self-determinant hierarchy shapes the T cell repertoire against this circulating self antigen in wild-type mice

Multicolor fate mapping of Langerhans cell homeostasis

Multifaceted contributions of epidermal langerhans cells to cutaneous carcinogenesis

Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions

Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice

Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells

Production of Extracellular Adenosine by CD73 Dendritic Cells is Crucial for Induction of Tolerance in Contact Hypersensitivity Reactions

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.

Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions.

Reproducibility Issues: Avoiding Pitfalls in Animal Inflammation Models.

Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice.

SOCS3 negatively regulates IL-6 signaling in vivo

Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming

Selective AhR knockout in langerin-expressing cells abates Langerhans cells and polarizes Th2/Tr1 in epicutaneous protein sensitization

Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation.

Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor.

Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.

Surmounting limited gene delivery into primary immune cell populations: Efficient cell type-specific adenoviral transduction by CAR.

TGF-β inhibitor Smad7 regulates dendritic cell-induced autoimmunity.

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity