List of works - Ian Mitchelle S De Vera

An alternate binding site for PPARγ ligands

scientific article published on 07 April 2014

Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates

scientific article published on 9 October 2012

Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

scientific article published on 08 December 2020

Backbone ¹H, ¹³C, and ¹⁵N chemical shift assignment for HIV-1 protease subtypes and multi-drug resistant variant MDR 769.

scientific article

Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate

scientific article

Correlating conformational shift induction with altered inhibitor potency in a multidrug resistant HIV-1 protease variant.

scientific article

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements.

scientific article published on 6 April 2018

Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection

scientific article published on 4 August 2015

Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1

scientific article published on 08 November 2018

Defining a conformational ensemble that directs activation of PPARγ.

scientific article

Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat

article

Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.

scientific article

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

scientific article

Effects of PRE and POST therapy drug-pressure selected mutations on HIV-1 protease conformational sampling.

scientific article published on 28 June 2014

Enhanced archaeal laccase production in recombinant Escherichia coli by modification of N-terminal propeptide and twin arginine translocation motifs

scientific article published on 3 July 2012

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1.

scientific article published on 29 April 2016

Inhibitor-Induced Conformational Shifts and Ligand-Exchange Dynamics for HIV-1 Protease Measured by Pulsed EPR and NMR Spectroscopy ⬇️

scientific article published on November 30, 2012

Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin-like proteins of Archaea

scientific article published on 26 July 2016

Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy

scientific article published on 26 October 2016

Pulsed EPR characterization of HIV-1 protease conformational sampling and inhibitor-induced population shifts

scientific article published on 22 October 2015

Pulsed EPR distance measurements in soluble proteins by site-directed spin labeling (SDSL).

scientific article published on 5 November 2013

Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA.

scientific article published on 23 August 2017

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.

scientific article published on 07 June 2017

List of works by Ian Mitchelle S De Vera

An alternate binding site for PPARγ ligands

Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates

Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

Backbone ¹H, ¹³C, and ¹⁵N chemical shift assignment for HIV-1 protease subtypes and multi-drug resistant variant MDR 769.

Conserved sequence-specific lincRNA-steroid receptor interactions drive transcriptional repression and direct cell fate

Correlating conformational shift induction with altered inhibitor potency in a multidrug resistant HIV-1 protease variant.

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements.

Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection

Defining a Canonical Ligand-Binding Pocket in the Orphan Nuclear Receptor Nurr1

Defining a conformational ensemble that directs activation of PPARγ.

Didehydro-Cortistatin A Inhibits HIV-1 by Specifically Binding to the Unstructured Basic Region of Tat

Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

Effects of PRE and POST therapy drug-pressure selected mutations on HIV-1 protease conformational sampling.

Enhanced archaeal laccase production in recombinant Escherichia coli by modification of N-terminal propeptide and twin arginine translocation motifs

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1.

Inhibitor-Induced Conformational Shifts and Ligand-Exchange Dynamics for HIV-1 Protease Measured by Pulsed EPR and NMR Spectroscopy ⬇️

Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin-like proteins of Archaea

Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy

Pulsed EPR characterization of HIV-1 protease conformational sampling and inhibitor-induced population shifts

Pulsed EPR distance measurements in soluble proteins by site-directed spin labeling (SDSL).

Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA.

Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.