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List of works by Christopher Exley

A biogeochemical cycle for aluminium? ⬇️

scientific article published on September 15, 2003

A mechanism for acute aluminium toxicity in fish.

scientific article published in August 1991

A molecular mechanism of aluminium-induced Alzheimer's disease?

scientific article

A possible mechanism of biological silicification in plants

scientific article published on 9 October 2015

A reappraisal of biological silicification in plants?

scientific article published on 15 March 2019

A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome

scientific article published on 11 November 2008

A systems biology approach to the blood-aluminium problem: the application and testing of a computational model

scientific article published on 12 June 2007

A vexing Commentary on the important issue of aluminium and Alzheimer' disease.

scientific article published in December 2006

ATP-promoted amyloidosis of an amyloid β peptide ⬇️

scientific article published on October 20, 1997

Action of Al-ATP on the isolated working rat heart.

scientific article

Acute toxicity of aluminium to fish eliminated in silicon-rich acid waters

scientific article published in Nature

Aggregation of the diabetes-related peptide ProIAPP1-48 measured by dynamic light scattering

scientific article published on 10 September 2018

Aluminium adjuvants and adverse events in sub-cutaneous allergy immunotherapy

scientific article published on 20 January 2014

Aluminium and Alzheimer's disease

scientific article published on 01 September 1993

Aluminium and breast cancer: Sources of exposure, tissue measurements and mechanisms of toxicological actions on breast biology

scientific article published on 13 July 2013

Aluminium and iron, but neither copper nor zinc, are key to the precipitation of beta-sheets of Abeta_{42} in senile plaque cores in Alzheimer's disease.

scientific article published on November 2006

Aluminium based adjuvants and their effects on mitochondria and lysosomes of phagocytosing cells

scientific article published on 9 August 2013

Aluminium in Brain Tissue in Epilepsy: A Case Report from Camelford

scientific article published on 16 June 2019

Aluminium in Brain Tissue in Multiple Sclerosis

scientific article published on 18 August 2018

Aluminium in brain tissue in autism

scientific article published on 26 November 2017

Aluminium in brain tissue in familial Alzheimer's disease

scientific article

Aluminium in human brain tissue from donors without neurodegenerative disease: A comparison with Alzheimer's disease, multiple sclerosis and autism

scientific article published on 08 May 2020

Aluminium in human brain tissue: how much is too much?

scientific article published on 29 August 2019

Aluminium in human breast tissue

scientific article

Aluminium in human sweat.

scientific article

Aluminium release during fluid warming

scientific article published on 01 June 2019

Aluminium, beta-amyloid and non-enzymatic glycosylation

scientific article published on 01 May 1995

Aluminium, iron and copper in human brain tissues donated to the Medical Research Council's Cognitive Function and Ageing Study

scientific article published in November 2011

Aluminium, iron, zinc and copper influence the in vitro formation of amyloid fibrils of Abeta42 in a manner which may have consequences for metal chelation therapy in Alzheimer's disease.

scientific article

Aluminium, tau and Alzheimer's disease

scientific article published in December 2007

Aluminium-adsorbed vaccines

scientific article published on 01 April 2006

Aluminium-based adjuvants should not be used as placebos in clinical trials ⬇️

scientific article published on August 25, 2011

Aluminium-containing DTP vaccines

scientific article published on 01 June 2004

Aluminium-induced phospholipid signal transduction pathway in Coffea arabica suspension cells and its amelioration by silicic acid

scientific article published on 7 November 2006

Aluminium: a natural adjuvant in Leishmania transmission via sand flies?

scientific article published on 19 May 2008

Aluminum Should Now Be Considered a Primary Etiological Factor in Alzheimer's Disease

scientific article published on 08 June 2017

Aluminum affects neural phenotype determination of embryonic neural progenitor cells

scientific article published on 30 July 2019

Aluminum and Alzheimer's disease

scientific article published on 01 December 2001

Aluminum and Amyloid-β in Familial Alzheimer's Disease

scientific article published on 01 January 2020

Aluminum and Neurofibrillary Tangle Co-Localization in Familial Alzheimer's Disease and Related Neurological Disorders

scientific article published on 08 September 2020

Aluminum content of human semen: implications for semen quality

scientific article published on 14 October 2014

Aluminum exposure at human dietary levels promotes vascular dysfunction and increases blood pressure in rats: A concerted action of NAD(P)H oxidase and COX-2.

scientific article

Aluminum exposure for 60days at human dietary levels impairs spermatogenesis and sperm quality in rats

scientific article published on 17 August 2017

Aluminum in antiperspirants: more than just skin deep

scientific article published on 01 December 2004

Aluminum in tobacco and cannabis and smoking-related disease

scientific article published on 01 March 2006

Aluminum inhibition of hexokinase activity in vitro: a study in biological availability.

scientific article published in June 1994

Aluminum's preferential binding site in proteins: sidechain of amino acids versus backbone interactions.

scientific article published on 11 November 2017

Aluminum-induced alterations of purinergic signalling in embryonic neural progenitor cells

scientific article published on 03 April 2020

Aluminum: a potential pro-oxidant in sunscreens/sunblocks?

scientific article published on 20 July 2007

Amyloid, aluminum and the aetiology of Alzheimer's disease

scientific article published in February 1996

An aluminium adjuvant in a vaccine is an acute exposure to aluminium

scientific article published on 18 September 2019

An interaction of β-amyloid with aluminium in vitro

article

Black paper for science

scientific article published in Nature

Brain burdens of aluminum, iron, and copper and their relationships with amyloid-β pathology in 60 human brains

scientific article published on January 2012

Bumblebee pupae contain high levels of aluminium

scientific article

Callose-associated silica deposition in Arabidopsis

scientific article published on 18 August 2016

Combined effects of smoking, anti-EBNA antibodies, and HLA-DRB1 1501 on multiple sclerosis risk ⬇️

scientific article published on August 24, 2010

Comment on "Avoidance of aluminum toxicity in freshwater snails involves intracellular silicon-aluminum biointeraction"

scientific article published on 01 July 2008

Comment on "the biological behaviour and bioavailability of aluminium in man" by N. D. Priest, JEM, 2004, 6, 375.

scientific article

Copper abolishes the beta-sheet secondary structure of preformed amyloid fibrils of amyloid-beta(42).

scientific article

Copper prevents amyloid-β(1-42) from forming amyloid fibrils under near-physiological conditions in vitro.

scientific article published on 13 February 2013

Copper(II) inhibits the formation of amylin amyloid in vitro

scientific article published on 17 October 2007

Correction to: Aluminium in human brain tissue: how much is too much?

scientific article published on 01 December 2019

Correction to: Unequivocal imaging of aluminium in human cells and tissues by an improved method using morin

scientific article published on 01 December 2019

Critical analysis of reference studies on aluminium-based adjuvants toxicokinetics

scientific article published on 30 May 2017

Critical analysis of reference studies on the toxicokinetics of aluminum-based adjuvants.

scientific article published on 28 December 2017

Darwin, natural selection and the biological essentiality of aluminium and silicon

scientific article

Direct and indirect identification of the formation of hydroxyaluminosilicates in acidic solutions

scientific article published on 01 November 2001

Does antiperspirant use increase the risk of aluminium-related disease, including Alzheimer's disease? ⬇️

scientific article published on March 1, 1998

Does either the gastrointestinal peptide PYY or the neuropeptide NPY bind aluminium?

scientific article published in April 2003

Egg White Hydrolysate as a functional food ingredient to prevent cognitive dysfunction in rats following long-term exposure to aluminum

scientific article published in Scientific Reports

Egg White Hydrolysate: A new putative agent to prevent vascular dysfunction in rats following long-term exposure to aluminum

scientific article published on 05 September 2019

Elevated brain aluminium and early onset Alzheimer's disease in an individual occupationally exposed to aluminium: a case report

scientific article published on 10 February 2014

Elevated urinary aluminium in current and past users of illicit heroin

scientific article published on 01 June 2007

Elevated urinary excretion of aluminium and iron in multiple sclerosis

scientific article published on 01 October 2006

Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide β-amyloid (1-42).

scientific article published on 26 March 2014

From Stock Bottle to Vaccine: Elucidating the Particle Size Distributions of Aluminum Adjuvants Using Dynamic Light Scattering

scientific article published on January 2016

Funding should recognize outcome, not income

scientific article published in Nature

Granulomas Following Subcutaneous Injection With Aluminum Adjuvant-Containing Products in Sheep

scientific article published on 31 October 2018

Guest editorial

scientific article published on 01 November 2011

Guest editorial Keele12.

scientific article published in April 2018

Guest editorial for the Special Issue from the Eleventh Keele Meeting on Aluminium

scientific article published on 01 November 2015

Guest editorial. 'The natural history of aluminium: from non-selection to natural selection'

scientific article published on 07 August 2009

Highly delayed systemic translocation of aluminum-based adjuvant in CD1 mice following intramuscular injections

scientific article published on 22 July 2015

Human exposure to aluminium

scientific article published on October 2013

Human pro-islet amyloid polypeptide (ProIAPP(1-48)) forms amyloid fibrils and amyloid spherulites in vitro

scientific article published on 9 June 2010

Hydroxyaluminosilicates and acute aluminium toxicity in fish

scientific article published on 01 November 1997

Identification of the aquaporin gene family in Cannabis sativa and evidence for the accumulation of silicon in its tissues

scientific article published on 11 June 2019

Imaging of aluminium and amyloid β in neurodegenerative disease

scientific article published on 25 April 2020

Insight into the cellular fate and toxicity of aluminium adjuvants used in clinically approved human vaccinations.

scientific article published on 12 August 2016

Intracellular Aluminium in Inflammatory and Glial Cells in Cerebral Amyloid Angiopathy: A Case Report

scientific article published on 24 April 2019

Intracellular tracing of amyloid vaccines through direct fluorescent labelling

scientific article

Intravascular ATP and coronary vasodilation in the isolated working rat heart

scientific article published on June 1999

Is callose required for silicification in plants?

article

Kinetic constraints in acute aluminium toxicity in the rainbow trout (Oncorhynchus mykiss)

scientific article published on 01 March 1996

Measurement by reversed-phase high-performance liquid chromatography of malondialdehyde in normal human urine following derivatisation with 2,4-dinitrophenylhydrazine

scientific article published in September 2003

Metal-mediated formation of fibrillar ABri amyloid

scientific article published on 01 December 2004

Metals accelerate the formation and direct the structure of amyloid fibrils of NAC.

scientific article published in September 2005

New insight into silica deposition in horsetail (Equisetum arvense).

scientific article

No effect of aluminium upon the hydrolysis of ATP in the coronary circulation of the isolated working rat heart

scientific article published on 01 August 1999

Non-invasive therapy to reduce the body burden of aluminium in Alzheimer's disease

scientific article

Non-linear dose-response of aluminium hydroxide adjuvant particles: Selective low dose neurotoxicity

scientific article published on 28 November 2016

Organosilicon therapy in Alzheimer's disease?

scientific article published in June 2007

Peer review versus editorial review and their role in innovative science

scientific article published on October 2012

Plasmin cleaves Abeta42 in vitro and prevents its aggregation into beta-pleated sheet structures.

scientific article

Polynuclear aluminium and acute aluminium toxicity in the fish

scientific article published on 01 April 1994

Prescription Infant Formulas Are Contaminated with Aluminium

article

Pro-oxidant Activity of Aluminum: Stabilization of the Aluminum Superoxide Radical Ion

scientific article published on 23 May 2011

Pro-oxidant activity of aluminum: Promoting the Fenton reaction by reducing Fe(III) to Fe(II)

scientific article published on 12 September 2012

RE: Nies, I., Hidalgo, K., Bondy, S. C., & Campbell, A. (2020). Distinctive Cellular Response to Aluminum Based Adjuvants. Environmental Toxicology and Pharmacology, 103404

scientific article published on 15 June 2020

RETRACTED: Letter to the editor

retracted paper

RETRACTED: Letter to the editor "[Toxicology (2017) 159 -159]

retracted scientific article published on 01 April 2018

Redox cycling of iron by Abeta42.

scientific article

Regular consumption of a silicic acid-rich water prevents aluminium-induced alterations of nitrergic neurons in mouse brain: histochemical and immunohistochemical studies

scientific article published in August 2012

Retraction Notice to "Letter to the editor"

item in Toxicology (1 December 2018)

Rough and tough. How does silicic acid protect horsetail from fungal infection?

scientific article published on 31 January 2018

Serum amyloid P component accelerates the formation and enhances the stability of amyloid fibrils in a physiologically significant under-saturated solution of amyloid-β42

scientific article published on 01 January 2012

Severe cerebral congophilic angiopathy coincident with increased brain aluminium in a resident of Camelford, Cornwall, UK

scientific article

Silicic acid (Si(OH)(4)) is a significant influence upon the atomic absorption signal of aluminium measured by graphite furnace atomic absorption spectrometry (GFAAS)

scientific article published on 01 November 2001

Silicic acid in drinking water prevents age-related alterations in the endothelium-dependent vascular relaxation modulating eNOS and AQP1 expression in experimental mice: an immunohistochemical study.

scientific article published on 21 November 2012

Silicic acid: The omniscient molecule

scientific article published on 14 February 2019

Silicon and bone

scientific article published on 12 February 2009

Silicon in life: whither biological silicification?

scientific article

Silicon in life:A bioinorganic solution to bioorganic essentiality1JD Birchall memorial lecture.1

scholarly article by Christopher Exley published February 1998 in Journal of Inorganic Biochemistry

Silicon species in seawater

scientific article

Silicon-rich mineral water as a non-invasive test of the 'aluminum hypothesis' in Alzheimer's disease

scientific article published in January 2013

Slow CCL2-dependent translocation of biopersistent particles from muscle to brain

scientific article published on 4 April 2013

Spherulites in human brain tissue are composed of β sheets of amyloid and resemble senile plaques

scientific article published on 01 January 2011

Spherulites of amyloid-beta42 in vitro and in Alzheimer's disease

scientific article

The Chemistry of Human Exposure to Aluminium

scientific article published on 01 January 2018

The Identification of Aluminum in Human Brain Tissue Using Lumogallion and Fluorescence Microscopy

scientific article published on 29 July 2016

The Thirteenth Keele Meeting on aluminium - future challenges in the Aluminium Age

scientific article published on 02 January 2020

The aluminium content of breast tissue taken from women with breast cancer

scientific article published on 01 June 2013

The aluminium content of infant formulas remains too high

scientific article

The aluminium-amyloid cascade hypothesis and Alzheimer's disease

scientific article

The binding, transport and fate of aluminium in biological cells.

scientific article

The cellular toxicity of aluminium

scientific article

The degradation of Abeta(25-35) by the serine protease plasmin is inhibited by aluminium.

scientific article

The immunobiology of aluminium adjuvants: how do they really work?

scientific article

The interaction of aluminium-based adjuvants with THP-1 macrophages in vitro: Implications for cellular survival and systemic translocation

scientific article published on 12 November 2019

The precipitation of mucin by aluminium ⬇️

scientific article published on 01 July 1998

The pro-oxidant activity of aluminum

scientific article published on 01 February 2004

The role of aluminum adjuvants in vaccines raises issues that deserve independent, rigorous and honest science

scientific article published on 01 August 2020

The safety of Cervarix?

scientific article published on 01 January 2017

The toxicity of aluminium in humans.

scientific article

There is (still) too much aluminium in infant formulas

scientific article

Toward understanding the mechanisms underlying the strong adjuvant activity of aluminium salt nanoparticles. Ruwona TB, Xu H, Li X, Taylor AN, Shi Y, Cui Z. Vaccine 2016;34:3059-67

scientific article published on 01 February 2017

Towards a model of non-equilibrium binding of metal ions in biological systems

scientific article published on 15 October 2008

Unequivocal identification of intracellular aluminium adjuvant in a monocytic THP-1 cell line

scientific article

Unequivocal imaging of aluminium in human cells and tissues by an improved method using morin

scientific article published on 28 August 2019

Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action

scientific article published on 07 November 2018

Unusual neuropathological features and increased brain aluminium in a resident of Camelford, UK.

scientific article

Urinary Excretion of Aluminium and Silicon in Secondary Progressive Multiple Sclerosis

scientific article

Use of Underarm Cosmetic Products in Relation to Risk of Breast Cancer: A Case-Control Study.

scientific article published on 6 June 2017

Visualising Silicon in Plants: Histochemistry, Silica Sculptures and Elemental Imaging

scientific article published on 24 April 2020

What happened to the epidemic in new variant Creutzfeldt-Jakob disease?

scientific article published on 25 February 2009

What is the mechanism of formation of hydroxyaluminosilicates?

scientific article published on August 2016

What is the risk of aluminium as a neurotoxin?

scientific article

When an aluminium adjuvant is not an aluminium adjuvant used in human vaccination programmes ⬇️

scientific article published on October 30, 2011

Why industry propaganda and political interference cannot disguise the inevitable role played by human exposure to aluminum in neurodegenerative diseases, including Alzheimer's disease

scientific article published in 2014

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