List of works - Marina Pizzi

1B/(-)IRE DMT1 expression during brain ischemia contributes to cell death mediated by NF-κB/RelA acetylation at Lys310

scientific article

A bioinformatics analysis of memory consolidation reveals involvement of the transcription factor c-rel

scientific article

Activation of Multiple Metabotropic Glutamate Receptor Subtypes Prevents NMDA-induced Excitotoxicity in Rat Hippocampal Slices

scientific article published on 01 July 1996

Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells.

scientific article published on 19 December 2007

Activation of dopamine D2 receptors linked to voltage-sensitive potassium channels reduces forskolin-induced cyclic AMP formation in rat pituitary cells

scientific article published on November 1, 1992

Antisense strategy unravels tau proteins as molecular risk factors for glutamate-induced neurodegeneration.

scientific article published on October 1994

Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia.

scientific article published in December 2006

Blockade of the tumor necrosis factor-related apoptosis inducing ligand death receptor DR5 prevents beta-amyloid neurotoxicity.

scientific article published on 16 August 2006

CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid.

scientific article published on 22 October 2014

CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.

scientific article published on March 2009

Differential expression of fetal and mature tau isoforms in primary cultures of rat cerebellar granule cells during differentiation in vitro

article

Distinct roles of diverse nuclear factor-kappaB complexes in neuropathological mechanisms.

scientific article published on 16 June 2006

EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide

scientific article published on 3 March 2015

Electrophysiological and metabolic effects of CHF5074 in the hippocampus: Protection against in vitro ischemia

scientific article published on 12 March 2014

Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line

scientific article published on December 2002

Functional and molecular evidence of myelin- and neuroprotection by thyroid hormone administration in experimental allergic encephalomyelitis.

scientific article published in August 2012

Glutamatergic innervation of rat skeletal muscle by supraspinal neurons: a new paradigm in spinal cord injury repair.

scientific article

Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes

scientific article

Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle.

scientific article

Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection.

scientific article

Inhibition of Glutamate-induced Neurotoxicity by a Tau Antisense Oligonucleotide in Primary Culture of Rat Cerebellar Granule Cells

article

Lack of vasoactive intestinal peptide-releasing property in prolactin cells from ovariectomized rats: contribution of post-transductional impairments.

scientific article

Late-onset Parkinsonism in NFκB/c-Rel-deficient mice

scientific article

Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3beta.

scientific article published on 7 March 2006

Leptin is induced in the ischemic cerebral cortex and exerts neuroprotection through NF-kappaB/c-Rel-dependent transcription.

scientific article

Mild Inflammatory Profile without Gliosis in the c-Rel Deficient Mouse Modeling a Late-Onset Parkinsonism.

scientific article published on 19 July 2017

Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson's Disease: Who's on First?

scientific article

Modification of the function of D1 and D2 dopamine receptors in striatum and nucleus accumbens of rats chronically treated with haloperidol

scientific article published on 01 May 1987

N-methyl-d-aspartate neurotoxicity in hippocampal slices: protection by aniracetam

scientific article published on 01 March 1995

NF-kappaB dimers in the regulation of neuronal survival.

scientific article published on January 2009

NF-kappaB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity.

scientific article

NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia.

scientific article

NF-kappaB pathway: a target for preventing beta-amyloid (Abeta)-induced neuronal damage and Abeta42 production

scientific article (publication date: April 2006)

NF-κB and epigenetic mechanisms as integrative regulators of brain resilience to anoxic stress.

scientific article published on 17 April 2012

NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases.

scientific article published on 20 May 2015

Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.

scientific article published in November 1996

Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat

scientific article published on 01 March 2000

Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation

scientific article published on 18 January 2017

Opposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta

scientific journal article

PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia

scientific article published on 13 July 2016

Pharmacological basis for dopamine D-2 receptor diversity.

scientific article

Pharmacological targeting of the β-amyloid precursor protein intracellular domain.

scientific article published on 09 April 2014

Possible new targets for GPCR modulation: allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms

scientific article

Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability.

scientific article published on January 2009

Postsynaptic D1 and D2 dopamine receptors are present in rabbit renal and mesenteric arteries

scientific article published on 01 October 1985

Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glutamate receptors.

scientific article published in May 2006

Repeated administration of (−) sulpiride and SCH 23390 differentially up-regulate D-1 and D-2 dopamine receptor function in rat mesostriatal areas but not in cortical-limbic brain regions

scientific article published on 01 June 1987

Requirement of oestrogens for the sensitivity of prolactin cells to vasoactive intestinal peptide in rats and man

scientific article published on February 1, 1992

Reversal of glutamate excitotoxicity by activation of PKC-associated metabotropic glutamate receptors in cerebellar granule cells relies on NR2C subunit expression.

scientific article

Review: Parkinson's disease: from synaptic loss to connectome dysfunction.

scientific article

Signal transduction and epigenetic mechanisms in the control of microglia activation during neuroinflammation

scientific article

Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells.

scientific article

Striatal adenylate cyclase-inhibiting dopamine D2 receptors are not affected by the aging process

scientific article published on 01 March 1987

Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains

scientific article published on 13 January 2018

Synergistic Association of Valproate and Resveratrol Reduces Brain Injury in Ischemic Stroke

scientific article published on 6 January 2018

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window.

scientific article

Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes.

scientific article

The Contribution of α-Synuclein Spreading to Parkinson's Disease Synaptopathy

scientific article published on 3 January 2017

The End Is the Beginning: Parkinson's Disease in the Light of Brain Imaging.

scientific article published on 10 October 2017

The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury

scientific article published on 4 November 2010

The inhibitor of I kappa B alpha phosphorylation BAY 11-7082 prevents NMDA neurotoxicity in mouse hippocampal slices.

scientific article

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

scientific article published in January 2011

Tolerance to hypoactivity and sensitization to hyperactivity after chronic treatment with a presynaptic dose of lisuride in rats

scientific article published on May 27, 1992

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate differently affect neuronal cytoarchitecture of rat cerebellar granule cells.

scientific article

α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons

scientific article published on 12 May 2015

List of works by Marina Pizzi

1B/(-)IRE DMT1 expression during brain ischemia contributes to cell death mediated by NF-κB/RelA acetylation at Lys310

A bioinformatics analysis of memory consolidation reveals involvement of the transcription factor c-rel

Activation of Multiple Metabotropic Glutamate Receptor Subtypes Prevents NMDA-induced Excitotoxicity in Rat Hippocampal Slices

Activation of NF-kappaB p65/c-Rel dimer is associated with neuroprotection elicited by mGlu5 receptor agonists against MPP(+) toxicity in SK-N-SH cells.

Activation of dopamine D2 receptors linked to voltage-sensitive potassium channels reduces forskolin-induced cyclic AMP formation in rat pituitary cells

Antisense strategy unravels tau proteins as molecular risk factors for glutamate-induced neurodegeneration.

Bim and Noxa are candidates to mediate the deleterious effect of the NF-kappa B subunit RelA in cerebral ischemia.

Blockade of the tumor necrosis factor-related apoptosis inducing ligand death receptor DR5 prevents beta-amyloid neurotoxicity.

CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid.

CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.

Differential expression of fetal and mature tau isoforms in primary cultures of rat cerebellar granule cells during differentiation in vitro

Distinct roles of diverse nuclear factor-kappaB complexes in neuropathological mechanisms.

EGFR amplified and overexpressing glioblastomas and association with better response to adjuvant metronomic temozolomide

Electrophysiological and metabolic effects of CHF5074 in the hippocampus: Protection against in vitro ischemia

Expression of functional NR1/NR2B-type NMDA receptors in neuronally differentiated SK-N-SH human cell line

Functional and molecular evidence of myelin- and neuroprotection by thyroid hormone administration in experimental allergic encephalomyelitis.

Glutamatergic innervation of rat skeletal muscle by supraspinal neurons: a new paradigm in spinal cord injury repair.

Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes

Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle.

Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection.

Inhibition of Glutamate-induced Neurotoxicity by a Tau Antisense Oligonucleotide in Primary Culture of Rat Cerebellar Granule Cells

Lack of vasoactive intestinal peptide-releasing property in prolactin cells from ovariectomized rats: contribution of post-transductional impairments.

Late-onset Parkinsonism in NFκB/c-Rel-deficient mice

Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3beta.

Leptin is induced in the ischemic cerebral cortex and exerts neuroprotection through NF-kappaB/c-Rel-dependent transcription.

Mild Inflammatory Profile without Gliosis in the c-Rel Deficient Mouse Modeling a Late-Onset Parkinsonism.

Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson's Disease: Who's on First?

Modification of the function of D1 and D2 dopamine receptors in striatum and nucleus accumbens of rats chronically treated with haloperidol

N-methyl-d-aspartate neurotoxicity in hippocampal slices: protection by aniracetam

NF-kappaB dimers in the regulation of neuronal survival.

NF-kappaB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity.

NF-kappaB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia.

NF-kappaB pathway: a target for preventing beta-amyloid (Abeta)-induced neuronal damage and Abeta42 production

NF-κB and epigenetic mechanisms as integrative regulators of brain resilience to anoxic stress.

NF-κB in Innate Neuroprotection and Age-Related Neurodegenerative Diseases.

Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.

Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat

Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation

Opposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta

PEA and luteolin synergistically reduce mast cell-mediated toxicity and elicit neuroprotection in cell-based models of brain ischemia

Pharmacological basis for dopamine D-2 receptor diversity.

Pharmacological targeting of the β-amyloid precursor protein intracellular domain.

Possible new targets for GPCR modulation: allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms

Post-ischemic brain damage: NF-kappaB dimer heterogeneity as a molecular determinant of neuron vulnerability.

Postsynaptic D1 and D2 dopamine receptors are present in rabbit renal and mesenteric arteries

Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glutamate receptors.

Repeated administration of (−) sulpiride and SCH 23390 differentially up-regulate D-1 and D-2 dopamine receptor function in rat mesostriatal areas but not in cortical-limbic brain regions

Requirement of oestrogens for the sensitivity of prolactin cells to vasoactive intestinal peptide in rats and man

Reversal of glutamate excitotoxicity by activation of PKC-associated metabotropic glutamate receptors in cerebellar granule cells relies on NR2C subunit expression.

Review: Parkinson's disease: from synaptic loss to connectome dysfunction.

Signal transduction and epigenetic mechanisms in the control of microglia activation during neuroinflammation

Soluble interleukin-6 (IL-6) receptor/IL-6 fusion protein enhances in vitro differentiation of purified rat oligodendroglial lineage cells.

Striatal adenylate cyclase-inhibiting dopamine D2 receptors are not affected by the aging process

Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains

Synergistic Association of Valproate and Resveratrol Reduces Brain Injury in Ischemic Stroke

Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window.

Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes.

The Contribution of α-Synuclein Spreading to Parkinson's Disease Synaptopathy

The End Is the Beginning: Parkinson's Disease in the Light of Brain Imaging.

The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury

The inhibitor of I kappa B alpha phosphorylation BAY 11-7082 prevents NMDA neurotoxicity in mouse hippocampal slices.

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

Tolerance to hypoactivity and sensitization to hyperactivity after chronic treatment with a presynaptic dose of lisuride in rats

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate differently affect neuronal cytoarchitecture of rat cerebellar granule cells.

α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons