List of works - Andreas Natsch

A Broad Diversity of Volatile Carboxylic Acids, Released by a Bacterial Aminoacylase from Axilla Secretions, as Candidate Molecules for the Determination of Human-Body Odor Type

scientific article published on 01 January 2006

A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation ⬇️

scientific article published on April 9, 2013

A fast Resazurin-based live viability assay is equivalent to the MTT-test in the KeratinoSens assay

scientific article published on 14 February 2015

A human chemosensory modality to detect peptides in the nose?

scientific article published on 11 December 2013

A species specific metabolism leading to male rat reprotoxicity of Cyclamen aldehyde: in vivo and in vitro evaluation

scientific article published in 2021

Accurate prediction of acute fish toxicity of fragrance chemicals with the RTgill-W1 cell assay

scientific article published on 4 November 2017

Analogues of the epoxy resin monomer diglycidyl ether of bisphenol F: effects on contact allergenic potency and cytotoxicity

scientific article published on 9 October 2012

Assessing skin sensitization hazard in mice and men using non-animal test methods

scientific article published on 23 December 2014

Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy.

scientific article published on 26 November 2015

Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice.

scientific article published on 14 May 2013

Body odour of monozygotic human twins: a common pattern of odorant carboxylic acids released by a bacterial aminoacylase from axilla secretions contributing to an inherited body odour type.

scientific article published on 05 August 2008

Chemical basis for the extreme skin sensitization potency of (E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one.

scientific article published on December 2010

Chemical reactivity and skin sensitization potential for benzaldehydes: can Schiff base formation explain everything?

Der menschlichen Duftchemie auf der Spur

Detection of potentially skin sensitizing hydroperoxides of linalool in fragranced products

scientific article published on 20 August 2014

Dual regulation of skin sensitizer-induced HMOX1 expression by Bach1 and Nrf2: Comparison to regulation of the AKR1C2-ARE element in the KeratinoSens cell line.

scientific article published on 2 August 2015

Epoxyalcohols: bioactivation and conjugation required for skin sensitization

scientific article published on 22 September 2014

Evaluating the performance of integrated approaches for hazard identification of skin sensitizing chemicals

scientific article published on 9 May 2014

Evaluating the sensitization potential of surfactants: integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach.

scientific article

Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing

scientific article

Fragrance raw materials and essential oils can reduce prostaglandin E(2) formation in keratinocytes and reconstituted human epidermis.

scientific article

High throughput kinetic profiling approach for covalent binding to peptides: application to skin sensitization potency of Michael acceptor electrophiles.

scientific article published in March 2009

Identification of odoriferous sulfanylalkanols in human axilla secretions and their formation through cleavage of cysteine precursors by a C-S lyase isolated from axilla bacteria.

scientific article published in July 2004

Integrated Testing Strategies (ITS) for safety assessment.

scientific article published on 19 November 2014

Isolation of a bacterial enzyme releasing axillary malodor and its use as a screening target for novel deodorant formulations.

scientific article

LC-MS-based characterization of the peptide reactivity of chemicals to improve the in vitro prediction of the skin sensitization potential

scientific article published on 12 September 2008

Lack of evidence for HLA-linked patterns of odorous carboxylic acids released from glutamine conjugates secreted in the human axilla.

scientific article published on 10 July 2010

Oxidative tryptophan modification by terpene- and squalene-hydroperoxides and a possible link to cross-reactions in diagnostic tests

scientific article published on 26 May 2015

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.

scientific article published on 20 March 2010

Predicting skin sensitizer potency based on in vitro data from KeratinoSens and kinetic peptide binding: global versus domain-based assessment

scientific article

Predicting the bioconcentration of fragrance ingredients by rainbow trout using measured rates of in vitro intrinsic clearance.

scientific article published on 4 August 2014

Reaction Chemistry to Characterize the Molecular Initiating Event in Skin Sensitization: A Journey to Be Continued.

scientific article

Relating Skin Sensitizing Potency to Chemical Reactivity: Reactive Michael Acceptors Inhibit NF-κB Signaling and Are Less Sensitizing than SNAr- and SN2- Reactive Chemicals ⬇️

scientific article published on November 7, 2011

Reporter cell lines for skin sensitization testing.

scientific article published on 21 July 2015

Respiratory sensitization: advances in assessing the risk of respiratory inflammation and irritation.

scientific article published on 05 May 2011

Response to the Letter to the Editor Regarding Our Article (Natsch et al., 2015)

scientific article published on 23 October 2015

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

scientific article

The Nrf2-Keap1-ARE toxicity pathway as a cellular sensor for skin sensitizers--functional relevance and a hypothesis on innate reactions to skin sensitizers.

scientific article published on 18 September 2009

The sensitivity of the KeratinoSens™ assay to evaluate plant extracts: a pilot study.

scientific article published on 18 February 2013

Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro.

scientific article published on 14 April 2007

Utility of Rat Liver S9 Fractions to Study Skin-Sensitizing Prohaptens in a Modified KeratinoSens Assay ⬇️

scientific article published on July 19, 2013

What Makes Us Smell: The Biochemistry of Body Odour and the Design of New Deodorant Ingredients

scientific article

List of works by Andreas Natsch

A Broad Diversity of Volatile Carboxylic Acids, Released by a Bacterial Aminoacylase from Axilla Secretions, as Candidate Molecules for the Determination of Human-Body Odor Type

A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation ⬇️

A fast Resazurin-based live viability assay is equivalent to the MTT-test in the KeratinoSens assay

A human chemosensory modality to detect peptides in the nose?

A species specific metabolism leading to male rat reprotoxicity of Cyclamen aldehyde: in vivo and in vitro evaluation

Accurate prediction of acute fish toxicity of fragrance chemicals with the RTgill-W1 cell assay

Analogues of the epoxy resin monomer diglycidyl ether of bisphenol F: effects on contact allergenic potency and cytotoxicity

Assessing skin sensitization hazard in mice and men using non-animal test methods

Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy.

Bayesian integrated testing strategy to assess skin sensitization potency: from theory to practice.

Body odour of monozygotic human twins: a common pattern of odorant carboxylic acids released by a bacterial aminoacylase from axilla secretions contributing to an inherited body odour type.

Chemical basis for the extreme skin sensitization potency of (E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one.

Chemical reactivity and skin sensitization potential for benzaldehydes: can Schiff base formation explain everything?

Der menschlichen Duftchemie auf der Spur

Detection of potentially skin sensitizing hydroperoxides of linalool in fragranced products

Dual regulation of skin sensitizer-induced HMOX1 expression by Bach1 and Nrf2: Comparison to regulation of the AKR1C2-ARE element in the KeratinoSens cell line.

Epoxyalcohols: bioactivation and conjugation required for skin sensitization

Evaluating the performance of integrated approaches for hazard identification of skin sensitizing chemicals

Evaluating the sensitization potential of surfactants: integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach.

Filling the concept with data: integrating data from different in vitro and in silico assays on skin sensitizers to explore the battery approach for animal-free skin sensitization testing

Fragrance raw materials and essential oils can reduce prostaglandin E(2) formation in keratinocytes and reconstituted human epidermis.

High throughput kinetic profiling approach for covalent binding to peptides: application to skin sensitization potency of Michael acceptor electrophiles.

Identification of odoriferous sulfanylalkanols in human axilla secretions and their formation through cleavage of cysteine precursors by a C-S lyase isolated from axilla bacteria.

Integrated Testing Strategies (ITS) for safety assessment.

Isolation of a bacterial enzyme releasing axillary malodor and its use as a screening target for novel deodorant formulations.

LC-MS-based characterization of the peptide reactivity of chemicals to improve the in vitro prediction of the skin sensitization potential

Lack of evidence for HLA-linked patterns of odorous carboxylic acids released from glutamine conjugates secreted in the human axilla.

Oxidative tryptophan modification by terpene- and squalene-hydroperoxides and a possible link to cross-reactions in diagnostic tests

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro.

Predicting skin sensitizer potency based on in vitro data from KeratinoSens and kinetic peptide binding: global versus domain-based assessment

Predicting the bioconcentration of fragrance ingredients by rainbow trout using measured rates of in vitro intrinsic clearance.

Reaction Chemistry to Characterize the Molecular Initiating Event in Skin Sensitization: A Journey to Be Continued.

Relating Skin Sensitizing Potency to Chemical Reactivity: Reactive Michael Acceptors Inhibit NF-κB Signaling and Are Less Sensitizing than SNAr- and SN2- Reactive Chemicals ⬇️

Reporter cell lines for skin sensitization testing.

Respiratory sensitization: advances in assessing the risk of respiratory inflammation and irritation.

Response to the Letter to the Editor Regarding Our Article (Natsch et al., 2015)

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

The Nrf2-Keap1-ARE toxicity pathway as a cellular sensor for skin sensitizers--functional relevance and a hypothesis on innate reactions to skin sensitizers.

The sensitivity of the KeratinoSens™ assay to evaluate plant extracts: a pilot study.

Utility and limitations of a peptide reactivity assay to predict fragrance allergens in vitro.

Utility of Rat Liver S9 Fractions to Study Skin-Sensitizing Prohaptens in a Modified KeratinoSens Assay ⬇️

What Makes Us Smell: The Biochemistry of Body Odour and the Design of New Deodorant Ingredients