List of works by Niamh M O'Boyle

'tieredScreen' - Layered Virtual Screening Tool for the Identification of Novel Estrogen Receptor Alpha Modulators.

scientific article

Analogues of the epoxy resin monomer diglycidyl ether of bisphenol F: effects on contact allergenic potency and cytotoxicity

scientific article published on 9 October 2012

Assessment of cross-reactivity of new less sensitizing epoxy resin monomers in epoxy resin-allergic individuals

scientific article published on 29 June 2016

Azetidin-2-ones: structures of anti-mitotic compounds based on the 1-(3,4,5-tri-meth-oxy-phen-yl)azetidin-2-one core

scientific article published on 03 July 2020

Combretastatin (CA)-4 and its novel analogue CA-432 impair T-cell migration through the Rho/ROCK signalling pathway

scientific article

Designed multiple ligands for cancer therapy.

scientific article published on January 2011

Epoxy resin monomers with reduced skin sensitizing potency

scientific article published on 02 June 2014

Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity

scientific article published on 01 May 2017

Lead identification of conformationally restricted benzoxepin type combretastatin analogs: synthesis, antiproliferative activity, and tubulin effects.

scientific article published on April 2010

Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90.

scientific article

Novel cis-restricted β-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro.

scientific article published on 10 December 2012

Piperlongumine (piplartine) and analogues: Antiproliferative microtubule-destabilising agents.

scientific article published on 16 September 2016

Special Issue "Anticancer Drugs"

scientific article published on 16 September 2019

Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents.

scientific article published on 17 December 2015

Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.

scientific article

Synthesis, biochemical and molecular modelling studies of antiproliferative azetidinones causing microtubule disruption and mitotic catastrophe.

scientific article

Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones.

scientific article published on 17 February 2011

The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.

scientific article published on 10 August 2010

β-Lactam analogues of combretastatin A-4 prevent metabolic inactivation by glucuronidation in chemoresistant HT-29 colon cancer cells.

scientific article published on 24 February 2017

β-Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand.

scientific article published on 17 November 2014

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