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List of works by Bruno Le Bizec

5α-Estrane-3β,17β-diol and 5β-estrane-3α,17β-diol: Definitive screening biomarkers to sign nandrolone abuse in cattle?

article

A relevant exposure to a food matrix contaminated environmentally by polychlorinated biphenyls induces liver and brain disruption in rats

scientific article published on 12 July 2016

A role for metabolomics in the antidoping toolbox?

scientific article published on 06 March 2020

APCI as an innovative ionization mode compared with EI and CI for the analysis of a large range of organophosphate esters using GC-MS/MS.

scientific article published on 21 November 2016

Accumulation of α-hexabromocyclododecane (α-HBCDD) in tissues of fast- and slow-growing broilers ( Gallus domesticus )

Ammonium Fluoride as Suitable Additive for HILIC-Based LC-HRMS Metabolomics

scientific article published on 27 November 2019

An investigation of the endocrine-disruptive effects of bisphenol a in human and rat fetal testes

scientific article

Analysis of glucuronide and sulfate steroids in urine by ultra-high-performance supercritical-fluid chromatography hyphenated tandem mass spectrometry

scientific article published on 4 March 2015

Analytical strategies to detect enobosarm administration in bovines.

scientific article published on 9 November 2016

Application of Gas Chromatography–Mass Spectrometry/Combustion/Isotope Ratio Mass Spectrometry (GC-MS/C/IRMS) To Detect the Abuse of 17β-Estradiol in Cattle ⬇️

scientific article published on July 18, 2013

Application of stable carbon isotope analysis to the detection of 17beta-estradiol administration to cattle.

scientific article published on 26 August 2005

Applying metabolomics to detect growth hormone administration in athletes: proof of concept

scientific article published on 04 April 2020

Auto-deconvolution and molecular networking of gas chromatography-mass spectrometry data

scientific article published on 09 November 2020

Basics of mass spectrometry based metabolomics.

scientific article published on 25 September 2014

Biosynthesis of 6beta-hydroxymethyltestosterone using bovine hepatocyte cultures.

scientific article published in September 2000

Blue sharks (Prionace glauca) as bioindicators of pollution and health in the Atlantic Ocean: Contamination levels and biochemical stress responses

scientific article published on 29 April 2016

Brazilian Ministry of Agriculture, Livestock and Food Supply (MAPA): strategies to tackle chemical food safety issues

article

Calf primary hepatocyte culture as a tool for anabolic steroid metabolism studies†

article

Characterization of nitrogen relationships between Sorghum bicolor and the root-hemiparasitic angiosperm Striga hermonthica (Del.) Benth. using K15 NO3 as isotopic tracer.

scientific article

Chlorination of bisphenol A: non-targeted screening for the identification of transformation products and assessment of estrogenicity in generated water

scientific article published on 25 October 2013

Clinical biochemical and hormonal profiling in plasma: a promising strategy to predict growth hormone abuse in cattle

scientific article published on 26 February 2015

Collision-induced dissociation of corticosteroids in electrospray tandem mass spectrometry and development of a screening method by high performance liquid chromatography/tandem mass spectrometry

article

Comparative study of low- versus high-resolution liquid chromatography-mass spectrometric strategies for measuring perfluorinated contaminants in fish

scientific article published on 27 June 2011

Comparison of different liquid chromatography stationary phases in LC-HRMS metabolomics for the detection of recombinant growth hormone doping control

scientific article published on 27 June 2011

Correction: Ingenbleek, L. et al. Regional Sub-Saharan Africa Total Diet Study in Benin, Cameroon, Mali, and Nigeria Reveals the Presence of 164 Mycotoxins and Other Secondary Metabolites in Foods

scientific article published on 28 February 2019

Criteria to distinguish between natural situations and illegal use of boldenone, boldenone esters and boldione in cattle

article

Detection and identification of 20-hydroxyecdysone metabolites in calf urine by liquid chromatography-high resolution or tandem mass spectrometry measurements and establishment of their kinetics of elimination after 20-hydroxyecdysone administration

scientific article published on 17 October 2008

Detection of 20-hydroxyecdysone in calf urine by comparative liquid chromatography/high-resolution mass spectrometry and liquid chromatography/tandem mass spectrometry measurements: application to the control of the potential misuse of ecdysteroids i

scientific article published on 01 December 2008

Detection of recombinant bovine somatotropin in milk and effect of industrial processes on its stability

scientific article published on 24 April 2010

Determination of MRL regulated corticosteroids in liver from various species using ultra high performance liquid chromatography–tandem mass spectrometry (UHPLC)

article

Determination of a large set of β-adrenergic agonists in animal matrices based on ion mobility and mass separations.

scientific article published on 25 August 2015

Determination of bisphenol A and related substitutes/analogues in human breast milk using gas chromatography-tandem mass spectrometry

scientific article published on 28 January 2015

Determination of hormonal growth promoters in bovine hair: comparison of liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry methods for estradiol benzoate and nortestosterone decanoate.

scientific article published on 17 October 2008

Determination of the exogenous character of testosterone in bovine urine by gas chromatography-combustion-isotope ratio mass spectrometry†

scientific article published on 01 December 1998

Determination of thyreostats in urine and thyroid gland by ultra high performance liquid chromatography tandem mass spectrometry.

scientific article published on 9 April 2009

Determination of toxaphene specific congeners in fish liver oil and feedingstuff using gas chromatography coupled to high resolution mass spectrometry.

scientific article published on 29 February 2008

Development and Application of a Probabilistic Risk-Benefit Assessment Model for Infant Feeding Integrating Microbiological, Nutritional, and Chemical Components

scientific article published on 12 April 2017

Development and application of stable carbon isotope analysis to the detection of cortisol administration in cattle

article

Development and validation of a method for fipronil residue determination in ovine plasma using 96-well plate solid-phase extraction and gas chromatography-tandem mass spectrometry.

scientific article published on 21 June 2008

Development and validation of a multi-residue method for the detection of a wide range of hormonal anabolic compounds in hair using gas chromatography–tandem mass spectrometry

article

Development and validation of a specific and sensitive gas chromatography tandem mass spectrometry method for the determination of bisphenol A residues in a large set of food items

article

Development and validation of an enzyme-linked immunosorbent assay for the detection of circulating antibodies raised against growth hormone as a consequence of rbST treatment in cows

article

Development of a metabonomic approach based on LC-ESI-HRMS measurements for profiling of metabolic changes induced by recombinant equine growth hormone in horse urine

article

Development of a molecular recognition based approach for multi-residue extraction of estrogenic endocrine disruptors from biological fluids coupled to liquid chromatography-tandem mass spectrometry measurement.

scientific article published on 21 September 2015

Development of an analytical strategy based on liquid chromatography-high resolution mass spectrometry for measuring perfluorinated compounds in human breast milk: application to the generation of preliminary data regarding perinatal exposure in Fra

scientific article

Developments in residue assay and metabolism study of growth-promoters by mass spectrometric analysis

article

Dietary exposure to perfluoroalkyl acids of specific French adult sub-populations: high seafood consumers, high freshwater fish consumers and pregnant women

scientific article published on 14 February 2014

Dietary exposure to polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls of the French population: Results of the second French Total Diet Study ⬇️

scientific article published on April 7, 2012

Dietary intake of non-dioxin-like PCBs (NDL-PCBs) in France, impact of maximum levels in some foodstuffs.

scientific article

Differential chemical profiling to identify ozonation by-products of estrone-sulfate and first characterization of estrogenicity in generated drinking water.

scientific article published on 18 April 2013

Differential global profiling as a new analytical strategy for revealing micropollutant treatment by-products: application to ethinylestradiol and chlorination water treatment.

scientific article

Dioxin-like, non-dioxin like PCB and PCDD/F contamination in European eel (Anguilla anguilla) from the Loire estuarine continuum: spatial and biological variabilities.

scientific article published on 6 December 2013

Direct analysis in real time - high resolution mass spectrometry (DART-HRMS): a high throughput strategy for identification and quantification of anabolic steroid esters.

scientific article published on 28 September 2014

Direct determination of recombinant bovine somatotropin in plasma from a treated goat by liquid chromatography/high-resolution mass spectrometry.

scientific article published in October 2008

Discrimination of Recombinant and Pituitary-Derived Bovine and Porcine Growth Hormones by Peptide Mass Mapping

scientific article published on 01 February 2004

Distribution of PCDD/Fs and dioxin-like PCBs in sediment and plants from a contaminated salt marsh (Tejo estuary, Portugal).

scientific article published on 2 October 2013

Distribution of persistent organic pollutants in serum, omental, and parietal adipose tissue of French women with deep infiltrating endometriosis and circulating versus stored ratio as new marker of exposure

scientific article

Early contamination of European flounder (Platichthys flesus) by PCDD/Fs and dioxin-like PCBs in European waters

scientific article published on 6 June 2014

Enantiomer-specific accumulation and depuration of α-hexabromocyclododecane (α-HBCDD) in chicken (Gallus gallus) as a tool to identify contamination sources.

scientific article

Endogenous nandrolone metabolites in human urine: preliminary results to discriminate between endogenous and exogenous origin.

scientific article published in February 2002

Enzymatic hydrolysis of conjugated steroid metabolites: search for optimum conditions using response surface methodology

article

Estranediols profiling in calves' urine after 17beta-nandrolone laureate ester administration.

scientific article published on 2 February 2010

Evidence that urinary excretion of thiouracil in adult bovine submitted to a cruciferous diet can give erroneous indications of the possible illegal use of thyrostats in meat production.

scientific article published in October 2006

Exposure assessment of French women and their newborn to brominated flame retardants: Determination of tri- to deca- polybromodiphenylethers (PBDE) in maternal adipose tissue, serum, breast milk and cord serum

article

Exposure assessment of French women and their newborns to tetrabromobisphenol-A: occurrence measurements in maternal adipose tissue, serum, breast milk and cord serum.

scientific article published on 14 September 2008

Exposure assessment of fetus and newborn to brominated flame retardants in France: preliminary data

scientific article

Exposure assessment of prepubertal children to steroid endocrine disruptors. 2. Determination of steroid hormones in milk, egg, and meat samples.

scientific article published on 16 April 2008

Fast and multiresidue determination of twenty glucocorticoids in bovine milk using ultra high performance liquid chromatography–tandem mass spectrometry

scientific article published on 15 April 2013

Fate and complex pathogenic effects of dioxins and polychlorinated biphenyls in obese subjects before and after drastic weight loss

scientific article

Food risk assessment for perfluoroalkyl acids and brominated flame retardants in the French population: Results from the second French total diet study

article

Gas chromatographic–mass spectrometric identification of main metabolites of stanozolol in cattle after oral and subcutaneous administration ⬇️

scientific article published on August 1, 1997

Gas chromatography coupled to mass spectrometry-based metabolomic to screen for anabolic practices in cattle: identification of 5α-androst-2-en-17-one as new biomarker of 4-androstenedione misuse

scientific article published on 01 January 2012

Gas chromatography/combustion/isotope ratio mass spectrometry to control the misuse of androgens in breeding animals: new derivatisation method applied to testosterone metabolites and precursors in urine samples.

scientific article published in January 2001

Germination Stimulants of Phelipanche ramosa in the Rhizosphere of Brassica napus Are Derived from the Glucosinolate Pathway

scientific article published on 01 July 2012

Global gene expression profiles induced by phytoestrogens in human breast cancer cells.

scientific article

High throughput identification and quantification of anabolic steroid esters by atmospheric solids analysis probe mass spectrometry for efficient screening of drug preparations

scientific article published on 27 May 2014

Human anogenital distance: an update on fetal smoke-exposure and integration of the perinatal literature on sex differences

scientific article published on 4 January 2016

Human dietary exposure to polycyclic aromatic hydrocarbons: Results of the second French Total Diet Study

article

Human testis steroidogenesis is inhibited by phthalates.

scientific article

Ibuprofen results in alterations of human fetal testis development

scientific article published on 10 March 2017

Identification of Cows Treated with Recombinant Bovine Somatotropin

scientific article published on 01 January 2010

Identification of Endogenous 19-Nortestosterone in Pregnant Ewes by Gas Chromatography–Mass Spectrometry

scientific article published on 01 May 1997

Identification of ractopamine residues in tissue and urine samples at ultra-trace level using liquid chromatography-positive electrospray tandem mass spectrometry.

scientific article published in July 2002

Impact of storage conditions on the urinary metabolomics fingerprint

scientific article published on 2 December 2016

Implementation of a semi-automated strategy for the annotation of metabolomic fingerprints generated by liquid chromatography-high resolution mass spectrometry from biological samples

scientific article

Improvement of estradiol esters monitoring in bovine hair by dansylation and liquid chromatography/tandem mass spectrometry analysis in multiple reaction monitoring and precursor ion scan modes

article

In utero exposure to cigarette smoke dysregulates human fetal ovarian developmental signalling

scientific article published on 20 May 2014

Innovative method for determination of 19 polycyclic aromatic hydrocarbons in food and oil samples using gas chromatography coupled to tandem mass spectrometry based on an isotope dilution approach

scientific article published on 16 March 2007

Ion Mobility Spectrometry in Food Analysis: Principles, Current Applications and Future Trends

scientific article published on 25 July 2019

Is the fresh water fish consumption a significant determinant of the internal exposure to perfluoroalkylated substances (PFAS)?

scientific article published in August 2014

Kinetic study of γ-hexabromocyclododecane orally given to laying hens (Gallus domesticus)

scientific article published on 02 August 2011

LC-HRMS based metabolomics screening model to detect various β-agonists treatments in bovines

article

LC–ESI-MS/MS determination of phenylurea and triazine herbicides and their dealkylated degradation products in oysters

scientific article published on 24 May 2006

Measurement of phthalates diesters in food using gas chromatography-tandem mass spectrometry.

scientific article published on 14 September 2015

Metabolomic approach based on liquid chromatography coupled to high resolution mass spectrometry to screen for the illegal use of estradiol and progesterone in cattle

scientific article published on 14 January 2011

Metabolomics as a potential new approach for investigating human reproductive disorders.

scientific article published on 17 May 2013

Metabolomics in food analysis: application to the control of forbidden substances

article

Milk and Urine Excretion of Polycyclic Aromatic Hydrocarbons and Their Hydroxylated Metabolites After a Single Oral Administration in Ruminants

scientific article published on 01 June 2007

Molecularly imprinted polymer applied to the selective isolation of urinary steroid hormones: An efficient tool in the control of natural steroid hormones abuse in cattle

article

Multi-functional sample preparation procedure for measuring phytoestrogens in milk, cereals, and baby-food by liquid-chromatography tandem mass spectrometry with subsequent determination of their estrogenic activity using transcriptomic assay.

scientific article published on 27 November 2008

Multi-residue extraction–purification procedure for corticosteroids in biological samples for efficient control of their misuse in livestock production

article

Multi-residue method for the determination of thyreostats in urine samples using liquid chromatography coupled to tandem mass spectrometry after derivatisation with 3-iodobenzylbromide.

scientific article published in September 2005

Multidimensional statistical analysis applied to electron ionization mass spectra to determine steroid stereochemistry.

scientific article

N-methyl-N-alkylsilyltrifluoroacetamide-I2 as a new derivatization reagent for anabolic steroid control.

scientific article

Neurodevelopmental and behavioral effects of nonylphenol exposure during gestational and breastfeeding period on F1 rats.

scientific article published on 21 July 2014

New multiresidue analytical method dedicated to trace level measurement of brominated flame retardants in human biological matrices.

scientific article

Occurrence of PCDD/Fs and dioxin-like PCBs in superficial sediment of Portuguese estuaries

scientific article published on 23 April 2014

Occurrence of priority and emerging organic compounds in fishes from the Rhone River (France).

scientific article published on 4 July 2012

Options for veterinary drug analysis using mass spectrometry.

scientific article published on 14 July 2009

PCDD/Fs and dioxin-like PCBs in sediment and biota from the Mondego estuary (Portugal).

scientific article

PFOS (perfluorooctanesulfonate) in serum is negatively associated with testosterone levels, but not with semen quality, in healthy men.

scientific article published on 18 December 2012

Patulin and secondary metabolite production by marine-derived Penicillium strains.

scientific article published on 13 July 2012

Perfluoroalkyl acid (PFAA) levels and profiles in breast milk, maternal and cord serum of French women and their newborns.

scientific article published on 28 July 2015

Perfluoroalkyl acid contamination and polyunsaturated fatty acid composition of French freshwater and marine fishes.

scientific article

Phthalates Exert Multiple Effects on Leydig Cell Steroidogenesis.

scientific article published on 12 November 2015

Pitfalls in trimethylsilylation of anabolic steroids. New derivatisation approach for residue at ultra-trace level.

scientific article published in February 2005

Pollutants in pet dogs: a model for environmental links to breast cancer

scientific article

Polychlorinated dibenzo-p-dioxins, furans, and biphenyls (PCDDs/PCDFs and PCBs) in breast milk and early childhood growth and IGF1

scientific article published on 02 March 2014

Potential of mass spectrometry metabolomics for chemical food safety.

scientific article published on January 2015

PrCYP707A1, an ABA catabolic gene, is a key component of Phelipanche ramosa seed germination in response to the strigolactone analogue GR24.

scientific article published on August 2012

Predicting PCDD/F and dioxin-like PCB contamination levels in bovine edible tissues from in vivo sampling.

scientific article published on 26 May 2010

Presence and metabolism of the anabolic steroid boldenone in various animal species: a review.

scientific article published on June 2004

Production of polyclonal antibodies directed to recombinant methionyl bovine somatotropin.

scientific article published on 3 December 2012

Public health risks and benefits associated with breast milk and infant formula consumption.

scientific article

Quality Assurance and Quality Control

article published in 2011

Regional Sub-Saharan Africa Total Diet Study in Benin, Cameroon, Mali and Nigeria Reveals the Presence of 164 Mycotoxins and Other Secondary Metabolites in Foods

scientific article published on 17 January 2019

Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar

scientific article published on 20 November 2013

Resveratrol inhibits steroidogenesis in human fetal adrenocortical cells at the end of first trimester

scientific article published on 26 August 2016

Screening halogenated environmental contaminants in biota based on isotopic pattern and mass defect provided by high resolution mass spectrometry profiling

scientific article

Screening of 4-androstenedione misuse in cattle by LC–MS/MS profiling of glucuronide and sulfate steroids in urine

article

Selective androgen receptor modulators: comparative excretion study of bicalutamide in bovine urine and faeces.

scientific article

Short-term effects of a perinatal exposure to the HBCDD α-isomer in rats: Assessment of early motor and sensory development, spontaneous locomotor activity and anxiety in pups

scientific article published on 5 September 2015

Simultaneous measurement of plasma concentrations and 13C-enrichment of short-chain fatty acids, lactic acid and ketone bodies by gas chromatography coupled to mass spectrometry.

scientific article

Solid-phase microextraction set-up for the analysis of liver volatolome to detect livestock exposure to micropollutants.

scientific article

Spatial Distribution of Lactococcus lactis Colonies Modulates the Production of Major Metabolites during the Ripening of a Model Cheese.

scientific article published on 23 October 2015

Specific characterization of non-steroidal selective androgen peceptor modulators using supercritical fluid chromatography coupled to ion-mobility mass spectrometry: application to the detection of enobosarm in bovine urine

article

Structural investigation and elucidation of new communesins from a marine-derived Penicillium expansum Link by liquid chromatography/electrospray ionization mass spectrometry.

scientific article published in December 2009

Studies on the determination of chlorotestosterone and its metabolites in bovine urine†

scientific article published on 01 December 1998

Study of natural and artificial corticosteroid phase II metabolites in bovine urine using HPLC-MS/MS.

scientific article published in September 2002

Study on polychlorobiphenyl serum levels in French consumers of freshwater fish

scientific article published on 28 October 2014

Studying variations in the PCDD/PCDF profile across various food products using multivariate statistical analysis.

scientific article published on 18 November 2005

Targeted phase II metabolites profiling as new screening strategy to investigate natural steroid abuse in animal breeding.

scientific article published on 11 December 2010

Thyreostatic drugs, stability in bovine and porcine urine.

scientific article published on 16 February 2012

Tissue Distribution and Transfer to Eggs of Ingested α-Hexabromocyclododecane (α-HBCDD) in Laying Hens (Gallus domesticus)

scientific article published on 03 March 2016

Toward a criterion for suspect thiouracil administration in animal husbandry.

scientific article published on 5 May 2011

Toxicological function of adipose tissue: focus on persistent organic pollutants.

scientific article published on 5 December 2012

Ultra high performance liquid chromatography/tandem mass spectrometry based identification of steroid esters in serum and plasma: an efficient strategy to detect natural steroids abuse in breeding and racing animals.

scientific article published on 10 February 2013

Ultra trace detection of a wide range of anabolic steroids in meat by gas chromatography coupled to mass spectrometry

scientific article published on 01 January 2000

Ultra-high performance liquid chromatography coupled to triple quadrupole mass spectrometry detection of naturally occurring thiouracil in urine of untreated livestock, domesticated animals and humans.

scientific article published on 21 January 2011

Ultra-trace quantification method for chlordecone in human fluids and tissues

scientific article published on 8 July 2015

Unambiguous identification of thiouracil residue in urine collected in non-treated bovine by tandem and high-resolution mass spectrometry

scientific article published on 01 January 2006

Urinary signature of pig carcasses with boar taint by liquid chromatography-high-resolution mass spectrometry.

scientific article published on 25 November 2016

Use of Volatile Compound Metabolic Signatures in Poultry Liver to Back-Trace Dietary Exposure to Rapidly Metabolized Xenobiotics

scientific article published on 13 July 2011

Versatile lipid profiling by liquid chromatography-high resolution mass spectrometry using all ion fragmentation and polarity switching. Preliminary application for serum samples phenotyping related to canine mammary cancer.

scientific article

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