List of works - Daniel S Strasser

2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.

scientific article

A fragment-based in situ combinatorial approach to identify high-affinity ligands for unknown binding sites

scientific article published on 01 August 2010

A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects.

scientific article

Attenuation of murine sclerodermatous models by the selective S1P receptor modulator cenerimod

scientific article published in Scientific Reports

Biomarker-guided clinical development of the first-in-class anti-inflammatory FPR2/ALX agonist ACT-389949.

scientific article published on 11 October 2016

Comparative epitope mapping with saturation transfer difference NMR of sialyl Lewis(a) compounds and derivatives bound to a monoclonal antibody.

scientific article

Differential effects of the dual orexin receptor antagonist almorexant and the GABA(A)-α1 receptor modulator zolpidem, alone or combined with ethanol, on motor performance in the rat.

scientific article published on 8 December 2010

Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention.

scientific article published on 21 February 2017

Eosinophilic oesophagitis: relevance of mast cell infiltration

scientific article published on 22 June 2018

Examining the role of endogenous orexins in hypothalamus-pituitary-adrenal axis endocrine function using transient dual orexin receptor antagonism in the rat.

scientific article published on 20 August 2012

Genetic screening for Niemann-Pick disease type C in adults with neurological and psychiatric symptoms: findings from the ZOOM study

scientific article published on 16 June 2013

Granulomatous lung inflammation is nanoparticle type-dependent

scientific article published on 11 January 2018

Identification of cathepsin L as a potential sex-specific biomarker for renal damage.

scientific article published on 28 February 2011

Kinetic and thermodynamic properties of MAG antagonists.

scientific article published on 16 March 2010

Modeling the Effect of the Selective S1P1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes.

scientific article published on 27 December 2016

Monitoring inflammatory heterogeneity with multiple biomarkers for multidimensional endotyping of asthma

scientific article published on 5 October 2017

Pharmacokinetic/Pharmacodynamic Modelling of Receptor Internalization with CRTH2 Antagonists to Optimize Dose Selection

scientific article published on 01 July 2016

Preclinical to clinical translation of cenerimod, a novel S1P1 receptor modulator, in systemic lupus erythematosus

scientific article published on 01 September 2020

Serum IL-5 and IL-13 consistently serve as the best predictors for the blood eosinophilia phenotype in adult asthmatics.

scientific article published on 06 April 2016

Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity

scientific article

List of works by Daniel S Strasser

2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.

A fragment-based in situ combinatorial approach to identify high-affinity ligands for unknown binding sites

A novel CRTH2 antagonist: Single- and multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ACT-453859 in healthy subjects.

Attenuation of murine sclerodermatous models by the selective S1P receptor modulator cenerimod

Biomarker-guided clinical development of the first-in-class anti-inflammatory FPR2/ALX agonist ACT-389949.

Comparative epitope mapping with saturation transfer difference NMR of sialyl Lewis(a) compounds and derivatives bound to a monoclonal antibody.

Differential effects of the dual orexin receptor antagonist almorexant and the GABA(A)-α1 receptor modulator zolpidem, alone or combined with ethanol, on motor performance in the rat.

Endothelin ETA Receptor Blockade, by Activating ETB Receptors, Increases Vascular Permeability and Induces Exaggerated Fluid Retention.

Eosinophilic oesophagitis: relevance of mast cell infiltration

Examining the role of endogenous orexins in hypothalamus-pituitary-adrenal axis endocrine function using transient dual orexin receptor antagonism in the rat.

Genetic screening for Niemann-Pick disease type C in adults with neurological and psychiatric symptoms: findings from the ZOOM study

Granulomatous lung inflammation is nanoparticle type-dependent

Identification of cathepsin L as a potential sex-specific biomarker for renal damage.

Kinetic and thermodynamic properties of MAG antagonists.

Modeling the Effect of the Selective S1P1 Receptor Modulator Ponesimod on Subsets of Blood Lymphocytes.

Monitoring inflammatory heterogeneity with multiple biomarkers for multidimensional endotyping of asthma

Pharmacokinetic/Pharmacodynamic Modelling of Receptor Internalization with CRTH2 Antagonists to Optimize Dose Selection

Preclinical to clinical translation of cenerimod, a novel S1P1 receptor modulator, in systemic lupus erythematosus

Serum IL-5 and IL-13 consistently serve as the best predictors for the blood eosinophilia phenotype in adult asthmatics.

Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity