Search filters

List of works by Harry Dolstra

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A frameshift polymorphism in P2X5 elicits an allogeneic cytotoxic T lymphocyte response associated with remission of chronic myeloid leukemia

scientific article

A polymorphism in the splice donor site of ZNF419 results in the novel renal cell carcinoma-associated minor histocompatibility antigen ZAPHIR.

scientific article

AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8 T cells for adoptive immunotherapy

scientific article published on 06 August 2018

Aberrant expression of the hematopoietic-restricted minor histocompatibility antigen LRH-1 on solid tumors results in efficient cytotoxic T cell-mediated lysis

scientific article published on 22 August 2008

An alternatively spliced CXCL16 isoform expressed by dendritic cells is a secreted chemoattractant for CXCR6+ cells

scientific article published on 24 February 2010

Association of disparities in known minor histocompatibility antigens with relapse-free survival and graft-versus-host disease after allogeneic stem cell transplantation

scientific article published on 27 September 2012

B and T lymphocyte attenuator mediates inhibition of tumor-reactive CD8+ T cells in patients after allogeneic stem cell transplantation

scientific article published on 25 May 2012

Bi-directional allelic recognition of the human minor histocompatibility antigen HB-1 by cytotoxic T lymphocytes

scientific article published on October 2002

Cell composition and expansion strategy can reduce the beneficial effect of AKT-inhibition on functionality of CD8+ T cells

scientific article published on 05 June 2020

Cellular adoptive immunotherapy after allogeneic stem cell transplantation

scientific article

Clinical-grade generation of active NK cells from cord blood hematopoietic progenitor cells for immunotherapy using a closed-system culture process

scientific article (publication date: 2011)

Clinically applicable CD34<sup>+</sup>-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses

scientific article published on 01 April 2021

Coinhibitory molecules in hematologic malignancies: targets for therapeutic intervention

scientific article published on 04 May 2012

Comprehensive Phenotyping of T Cells Using Flow Cytometry

scientific article published on 04 February 2019

Concurrent Detection of Circulating Minor Histocompatibility Antigen-Specific CD8+ T Cells in SCT Recipients by Combinatorial Encoding MHC Multimers ⬇️

scientific article published on June 24, 2011

Defining early human NK cell developmental stages in primary and secondary lymphoid tissues

scientific article

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Efficient activation of LRH-1-specific CD8+ T-cell responses from transplanted leukemia patients by stimulation with P2X5 mRNA-electroporated dendritic cells

scientific article

Efficient nontoxic delivery of PD-L1 and PD-L2 siRNA into dendritic cell vaccines using the cationic lipid SAINT-18.

scientific article published in May 2015

Ex Vivo Generated Natural Killer Cells Acquire Typical Natural Killer Receptors and Display a Cytotoxic Gene Expression Profile Similar to Peripheral Blood Natural Killer Cells ⬇️

scientific article published on July 17, 2012

Ex vivo generation of interstitial and Langerhans cell-like dendritic cell subset-based vaccines for hematological malignancies

scientific article published on June 2014

Expression of C-IAP1, C-IAP2 and SURVIVIN discriminates different types of lymphoid malignancies.

scientific article

Expression of P2X5 in lymphoid malignancies results in LRH-1-specific cytotoxic T-cell-mediated lysis.

scientific article

Extensive natural killer cell receptor phenotyping on NK and T cells discloses differences in RA and PsA, potentially mirroring diverse immunoregulatory functions.

scientific article published on 23 November 2011

Generation of autologous cytotoxic and helper T-cell responses against the B-cell leukemia-associated antigen HB-1: relevance for precursor B-ALL-specific immunotherapy

scientific article published on 3 July 2003

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo

scientific article published on 6 February 2017

High log-scale expansion of functional human natural killer cells from umbilical cord blood CD34-positive cells for adoptive cancer immunotherapy

scientific article

Homing characteristics of donor T cells after experimental allogeneic bone marrow transplantation and posttransplantation therapy for multiple myeloma

scientific article published on 21 December 2012

IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor-derived NK cells

scientific article published on 03 November 2020

Immune checkpoint molecules in acute myeloid leukaemia: managing the double-edged sword

scientific article published on 9 January 2018

Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients

scientific article published on 2 June 2013

Immunotherapeutic approaches to treat multiple myeloma

scientific article published on 11 December 2013

Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation

scientific article published on 19 August 2012

Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation

scientific article published on 29 November 2017

Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy

scientific article

Intratumoral rhIL-12 administration in head and neck squamous cell carcinoma patients induces B cell activation

scientific article published in November 2008

LB-ARHGDIB-1R as a novel minor histocompatibility antigen for therapeutic application

scientific article published on 11 June 2015

MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis

scientific article published on 01 July 2019

Monitoring of developing graft-versus-host disease mediated by herpes simplex virus thymidine kinase gene-transduced T cells

scientific article published in March 2003

Multicenter analyses demonstrate significant clinical effects of minor histocompatibility antigens on GvHD and GvL after HLA-matched related and unrelated hematopoietic stem cell transplantation

scientific article published on 10 June 2013

Natural Killer Cell Differentiation from Hematopoietic Stem Cells: A Comparative Analysis of Heparin- and Stromal Cell–Supported Methods ⬇️

scientific article published on December 7, 2011

Natural killer cells generated from cord blood hematopoietic progenitor cells efficiently target bone marrow-residing human leukemia cells in NOD/SCID/IL2Rg(null) mice

scientific article (publication date: 2013)

Noninvasive Imaging of Tumor PD-L1 Expression Using Radiolabeled Anti-PD-L1 Antibodies

scientific article

PD-1/PD-L1 interactions contribute to functional T-cell impairment in patients who relapse with cancer after allogeneic stem cell transplantation

scientific article published on 9 June 2011

Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations

scientific article published in June 2007

Quantification of the HA-1 gene product at the RNA level; relevance for immunotherapy of hematological malignancies

scientific article published on January 1, 2003

Refinement of molecular approaches to improve the chance of identification of hematopoietic-restricted minor histocompatibility antigens

scientific article

T cells expressing the activating NK-cell receptors KIR2DS4, NKG2C and NKG2D are elevated in paroxysmal nocturnal hemoglobinuria and cytotoxic toward hematopoietic progenitor cell lines ⬇️

scientific article published on April 21, 2011

TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer

scientific article published on 08 November 2020

The Aryl Hydrocarbon Receptor Antagonist StemRegenin1 Improves In Vitro Generation of Highly Functional Natural Killer Cells from CD34(+) Hematopoietic Stem and Progenitor Cells

scientific article published on 28 September 2015

The aryl hydrocarbon receptor antagonist StemRegenin 1 promotes human plasmacytoid and myeloid dendritic cell development from CD34+ hematopoietic progenitor cells

scientific article published on 24 January 2014

The magnitude of cytokine production by stimulated CD56+ cells is associated with early stages of systemic sclerosis

scientific article published on 8 September 2016

Toward targeting B cell cancers with CD4+ CTLs: identification of a CD19-encoded minor histocompatibility antigen using a novel genome-wide analysis

scientific article published on 10 November 2008

Umbilical cord blood-derived cellular products for cancer immunotherapy

scientific article published on 18 March 2015

siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8(+) T cells in NOD/SCID/IL2Rg(null) mice

scientific article published on 28 February 2015

siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells

scientific article published on 3 August 2010

Paulina is supported by:

About Paulina

Help