List of works - Bruno Lucas

A molecular map of T cell development.

scientific article published in August 1998

A novel CD45RA+CD4+ transient thymic subpopulation in MRL-lpr/lpr mice: its relation to non-proliferating CD4-CD8-CD45RA+ tumor cells

scientific article published on 01 January 1993

Adaptive Immune-like γ/δ T Lymphocytes Share Many Common Features with Their α/β T Cell Counterparts.

scientific article published on 29 June 2015

An 8-bp deletion in mNOTCH4 intron 10 leads to its retention in mRNA and to synthesis of a truncated protein

scientific article published on 21 November 2005

Autoimmunity during thymectomy-induced lymphopenia: role of thymus ablation and initial effector T cell activation timing in nonobese diabetic mice

scientific article published on 01 October 2009

Bacteria-driven peribronchial lymphoid neogenesis in bronchiectasis and cystic fibrosis

scientific article published on 26 April 2017

CD4low TCRint thymocytes do not belong to the CD8 lineage maturation pathway.

scientific article

Calcium-mediated shaping of naive CD4 T-cell phenotype and function.

scientific article published on 14 December 2017

Cell expansion and growth arrest phases during the transition from precursor (CD4-8-) to immature (CD4+8+) thymocytes in normal and genetically modified mice

scientific article published on 01 May 1995

Conversion of naive T cells to a memory-like phenotype in lymphopenic hosts is not related to a homeostatic mechanism that fills the peripheral naive T cell pool.

scientific article published in May 2002

CpG methylation changes within the IL2RA promoter in type 1 diabetes of childhood onset

scientific article

Cross-presentation by dendritic cells from live cells induces protective immune responses in vivo.

scientific article published on 22 March 2010

Crucial role of inflammatory monocytes in antitumor immunity

scientific article published on 9 October 2013

Differential requirement of caspases during naive T cell proliferation

scientific article published on 01 October 2002

Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

scientific article published on 01 March 1999

Foxo1 Is a T Cell-Intrinsic Inhibitor of the RORγt-Th17 Program

scientific article published on 13 July 2015

Foxp3-independent loss of regulatory CD4+ T-cell suppressive capacities induced by self-deprivation

scientific article published in May 2012

Highly self-reactive naive CD4 T cells are prone to differentiate into regulatory T cells

scientific article published in January 2013

IL-2 and IL-7 determine the homeostatic balance between the regulatory and conventional CD4+ T cell compartments during peripheral T cell reconstitution.

scientific article

In vivo T cell response to viral superantigen. Selective migration rather than proliferation

scientific article published on 01 June 1996

Inflammatory monocytes are potent antitumor effectors controlled by regulatory CD4+ T cells.

scientific article published on 22 July 2013

Intravenous immunoglobulins in patients with COVID-19-associated moderate-to-severe acute respiratory distress syndrome (ICAR): multicentre, double-blind, placebo-controlled, phase 3 trial

scientific article published on 11 November 2021

Long-term reversal of established autoimmunity upon transient blockade of the LFA-1/intercellular adhesion molecule-1 pathway.

scientific article published in April 2002

Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development

scientific article published on 26 June 2009

Macrophages Induce Long-Term Trapping of γδ T Cells with Innate-like Properties within Secondary Lymphoid Organs in the Steady State

scientific article published on 4 August 2017

Multiple survival signals are delivered by dendritic cells to naive CD4+ T cells

scientific article published on 01 September 2005

NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

scientific article published on 01 December 2002

Normal sequence of phenotypic transitions in one cohort of 5-bromo-2'-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression

scientific article published on 01 November 1993

On the role of MHC class II molecules in the survival and lymphopenia-induced proliferation of peripheral CD4+ T cells.

scientific article

Peripheral CD8+CD25+ T lymphocytes from MHC class II-deficient mice exhibit regulatory activity

scientific article published on 01 July 2005

Production, selection, and maturation of thymocytes with high surface density of TCR

scientific article published on 01 July 1994

Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota.

scientific article

Quantitative and qualitative adjustment of thymic T cell production by clonal expansion of premigrant thymocytes

scientific article published on 01 February 2002

Recruitment of CXCR3+ T cells into injured tissues in adult IgA vasculitis patients correlates with disease activity

scientific article published on 08 February 2019

Regulatory CD4+ T cells are crucial for preventing CD8+ T cell-mediated autoimmunity

scientific article published on 01 June 2008

Regulatory T Cell Stability and Migration Are Dependent on mTOR

scientific article published on 24 August 2020

Self-recognition is crucial for maintaining the peripheral CD4+ T-cell pool in a nonlymphopenic environment

scientific article published on 09 March 2006

Sepsis-induced expansion of granulocytic myeloid-derived suppressor cells promotes tumour growth through Toll-like receptor 4.

scientific article published on 14 May 2016

Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo.

scientific article published in March 2004

T Cells Contribute to Tumor Progression by Favoring Pro-Tumoral Properties of Intra-Tumoral Myeloid Cells in a Mouse Model for Spontaneous Melanoma ⬇️

scientific article published on May 25, 2011

T-cell repertoire: political correctness in the immune system.

scientific article published on July 1996

TCR signaling events are required for maintaining CD4 regulatory T cell numbers and suppressive capacities in the periphery

scientific article published on 7 November 2014

TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type.

scientific article published in September 2000

Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells

scientific article published in February 2008

Thymic medulla epithelial cells acquire specific markers by post-mitotic maturation.

scientific article published in January 1996

Timing and casting for actors of thymic negative selection

scientific article published on 01 February 1999

Tolerance to proinsulin-2 is due to radioresistant thymic cells

scientific article published on 01 July 2006

Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis.

scientific article published on 27 October 2017

Treatment of Uveitis by In Situ Administration of Ex Vivo-Activated Polyclonal Regulatory T Cells.

scientific article published on 29 January 2016

Treatment of collagen-induced arthritis by Natura-alpha via regulation of Th-1/Th-17 responses

scientific article published on 01 February 2010

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

scientific article published on November 1996

List of works by Bruno Lucas

A molecular map of T cell development.

A novel CD45RA+CD4+ transient thymic subpopulation in MRL-lpr/lpr mice: its relation to non-proliferating CD4-CD8-CD45RA+ tumor cells

Adaptive Immune-like γ/δ T Lymphocytes Share Many Common Features with Their α/β T Cell Counterparts.

An 8-bp deletion in mNOTCH4 intron 10 leads to its retention in mRNA and to synthesis of a truncated protein

Autoimmunity during thymectomy-induced lymphopenia: role of thymus ablation and initial effector T cell activation timing in nonobese diabetic mice

Bacteria-driven peribronchial lymphoid neogenesis in bronchiectasis and cystic fibrosis

CD4low TCRint thymocytes do not belong to the CD8 lineage maturation pathway.

Calcium-mediated shaping of naive CD4 T-cell phenotype and function.

Cell expansion and growth arrest phases during the transition from precursor (CD4-8-) to immature (CD4+8+) thymocytes in normal and genetically modified mice

Conversion of naive T cells to a memory-like phenotype in lymphopenic hosts is not related to a homeostatic mechanism that fills the peripheral naive T cell pool.

CpG methylation changes within the IL2RA promoter in type 1 diabetes of childhood onset

Cross-presentation by dendritic cells from live cells induces protective immune responses in vivo.

Crucial role of inflammatory monocytes in antitumor immunity

Differential requirement of caspases during naive T cell proliferation

Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

Foxo1 Is a T Cell-Intrinsic Inhibitor of the RORγt-Th17 Program

Foxp3-independent loss of regulatory CD4+ T-cell suppressive capacities induced by self-deprivation

Highly self-reactive naive CD4 T cells are prone to differentiate into regulatory T cells

IL-2 and IL-7 determine the homeostatic balance between the regulatory and conventional CD4+ T cell compartments during peripheral T cell reconstitution.

In vivo T cell response to viral superantigen. Selective migration rather than proliferation

Inflammatory monocytes are potent antitumor effectors controlled by regulatory CD4+ T cells.

Intravenous immunoglobulins in patients with COVID-19-associated moderate-to-severe acute respiratory distress syndrome (ICAR): multicentre, double-blind, placebo-controlled, phase 3 trial

Long-term reversal of established autoimmunity upon transient blockade of the LFA-1/intercellular adhesion molecule-1 pathway.

Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development

Macrophages Induce Long-Term Trapping of γδ T Cells with Innate-like Properties within Secondary Lymphoid Organs in the Steady State

Multiple survival signals are delivered by dendritic cells to naive CD4+ T cells

NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

Normal sequence of phenotypic transitions in one cohort of 5-bromo-2'-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression

On the role of MHC class II molecules in the survival and lymphopenia-induced proliferation of peripheral CD4+ T cells.

Peripheral CD8+CD25+ T lymphocytes from MHC class II-deficient mice exhibit regulatory activity

Production, selection, and maturation of thymocytes with high surface density of TCR

Profiling the lymphoid-resident T cell pool reveals modulation by age and microbiota.

Quantitative and qualitative adjustment of thymic T cell production by clonal expansion of premigrant thymocytes

Recruitment of CXCR3+ T cells into injured tissues in adult IgA vasculitis patients correlates with disease activity

Regulatory CD4+ T cells are crucial for preventing CD8+ T cell-mediated autoimmunity

Regulatory T Cell Stability and Migration Are Dependent on mTOR

Self-recognition is crucial for maintaining the peripheral CD4+ T-cell pool in a nonlymphopenic environment

Sepsis-induced expansion of granulocytic myeloid-derived suppressor cells promotes tumour growth through Toll-like receptor 4.

Suppression of CD4+ T lymphocyte effector functions by CD4+CD25+ cells in vivo.

T Cells Contribute to Tumor Progression by Favoring Pro-Tumoral Properties of Intra-Tumoral Myeloid Cells in a Mouse Model for Spontaneous Melanoma ⬇️

T-cell repertoire: political correctness in the immune system.

TCR signaling events are required for maintaining CD4 regulatory T cell numbers and suppressive capacities in the periphery

TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type.

Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells

Thymic medulla epithelial cells acquire specific markers by post-mitotic maturation.

Timing and casting for actors of thymic negative selection

Tolerance to proinsulin-2 is due to radioresistant thymic cells

Transgenic Mice Expressing Human Proteinase 3 Exhibit Sustained Neutrophil-Associated Peritonitis.

Treatment of Uveitis by In Situ Administration of Ex Vivo-Activated Polyclonal Regulatory T Cells.

Treatment of collagen-induced arthritis by Natura-alpha via regulation of Th-1/Th-17 responses

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.