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List of works by Florian Gruber

'Don't be so over-protective!'

scientific article

12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function.

scientific article

1st Science Days of the Austrian Society of Dermatology and Venereology (ÖGDV Forschungstage)

scientific article published on 01 April 2016

2nd Science Days of the Austrian Society of Dermatology and Venereology (ÖGDV Forschungstage)

scientific article published on 01 April 2017

A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids

scientific article published on 13 November 2018

A simplified procedure for semi-targeted lipidomic analysis of oxidized phosphatidylcholines induced by UVA irradiation

scientific article

ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging

scientific article published on 03 January 2020

Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice

scientific article published on 06 February 2014

Airway inflammation induced after allergic poly-sensitization can be prevented by mucosal but not by systemic administration of poly-peptides.

scientific article published on 6 May 2008

Analysis of the Secretome of Apoptotic Peripheral Blood Mononuclear Cells: Impact of Released Proteins and Exosomes for Tissue Regeneration.

scientific article

Anti-acanthamoeba efficacy and toxicity of miltefosine in an organotypic skin equivalent.

scientific article published on 23 June 2009

Autophagic Control of Skin Aging

scientific article published on 30 July 2019

Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo.

scientific article published on 18 December 2016

Autophagy deficient melanocytes display a senescence associated secretory phenotype that includes oxidized lipid mediators

scientific article published on 11 October 2016

Autophagy is induced by UVA and promotes removal of oxidized phospholipids and protein aggregates in epidermal keratinocytes.

scientific article published on 22 January 2013

Bioinformatics approach for choosing the correct reference genes when studying gene expression in human keratinocytes

scientific article published on 15 May 2015

Blocking negative effects of senescence in human skin fibroblasts with a plant extract.

scientific article published on 11 April 2018

Cornification of nail keratinocytes requires autophagy for bulk degradation of intracellular proteins while sparing components of the cytoskeleton

scientific article published on 01 February 2019

Different pro-angiogenic potential of γ-irradiated PBMC-derived secretome and its subfractions

scientific article published in Scientific Reports

Dual role of the antioxidant enzyme peroxiredoxin 6 in skin carcinogenesis

scientific article published on 10 April 2013

Dying blood mononuclear cell secretome exerts antimicrobial activity.

scientific article published on 11 August 2016

Extracellular Vesicles in Human Skin: Cross-Talk from Senescent Fibroblasts to Keratinocytes by miRNAs

scientific article published on 18 June 2019

Flagellin is the principal inducer of the antimicrobial peptide S100A7c (psoriasin) in human epidermal keratinocytes exposed to Escherichia coli

scientific article

Freckles and solar lentigines have different risk factors in Caucasian women

scientific article published on 28 August 2012

Functional MC1R-Gene Variants Are Associated with Increased Risk for Severe Photoaging of Facial Skin

article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2.

scientific article published on 19 January 2017

Hepatocyte Growth Factor Establishes Autocrine and Paracrine Feedback Loops for the Protection of Skin Cells after UV Irradiation

High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan

scientific article published on 19 April 2013

Histamine suppresses epidermal keratinocyte differentiation and impairs skin barrier function in a human skin model

scientific article published on 15 November 2012

Identification of a novel exon encoding the amino-terminus of the predominant caspase-5 variants

scientific article published in 2006

Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.

scientific article

Inactivation of VEGF in mammary gland epithelium severely compromises mammary gland development and function

scientific journal article

Inactivation of autophagy leads to changes in sebaceous gland morphology and function

scientific article published on 20 August 2018

Involvement of cutaneous SR-B1 in skin lipid homeostasis

scientific article published on 13 March 2019

Knockdown of filaggrin impairs diffusion barrier function and increases UV sensitivity in a human skin model

scientific article published on 6 May 2010

MC1R gene polymorphism affects skin color and phenotypic features related to sun sensitivity in a population of French adult women

scientific article published in November 2009

Multi-hit inhibition of circulating and cell-associated components of the toll-like receptor 4 pathway by oxidized phospholipids.

scientific article

NAB2, a corepressor of EGR-1, inhibits vascular endothelial growth factor-mediated gene induction and angiogenic responses of endothelial cells.

scientific article

NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells

scientific article

Nrf2 deficiency causes lipid oxidation, inflammation, and matrix-protease expression in DHA-supplemented and UVA-irradiated skin fibroblasts

scientific article published on 13 May 2015

Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

scientific article published on 06 March 2020

Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein.

scientific article published on 30 September 2003

Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions

scientific article published on 14 September 2006

Peanut lipids display potential adjuvanticity by triggering a pro-inflammatory response in human keratinocytes

scientific article published on 27 May 2018

Photooxidation Generates Biologically Active Phospholipids That Induce Heme Oxygenase-1 in Skin Cells

scientific article published in Journal of Biological Chemistry

Polymorphismes du MC1R et photovieillissement du visage

Retinal pigment epithelium cells produce VEGF in response to oxidized phospholipids through mechanisms involving ATF4 and protein kinase CK2.

scientific article

Retinoic acid increases the expression of p53 and proapoptotic caspases and sensitizes keratinocytes to apoptosis: a possible explanation for tumor preventive action of retinoids

scientific article published in September 2004

SNEV(Prp19/PSO4) deficiency increases PUVA-induced senescence in mouse skin

scientific article published on 14 December 2015

Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype.

scientific article

Sulfate-based lipids: Analysis of healthy human fluids and cell extracts

scientific article published on 22 March 2019

Suppression of autophagy dysregulates the antioxidant response and causes premature senescence of melanocytes

scientific article published on 7 October 2014

Suppression of epithelial autophagy compromises the homeostasis of sweat glands during aging.

scientific article published on 20 March 2018

Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth

scientific article

Targeted deletion of Atg5 reveals differential roles of autophagy in keratin K5-expressing epithelia.

scientific article published on 2 December 2012

The impact of recent advances in lipidomics and redox lipidomics on dermatological research

scientific article published on 18 April 2019

Tyrosinase-Cre-Mediated Deletion of the Autophagy Gene Atg7 Leads to Accumulation of the RPE65 Variant M450 in the Retinal Pigment Epithelium of C57BL/6 Mice

scientific article

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