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Authors whose works are in public domain in at least one jurisdiction

List of works by Barry C Finzel

A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides

scientific article

A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 A Streptomyces rubiginosus structures with xylitol and D-xylose

scientific article

An independent crystallographic refinement of porcine phospholipase A2 at 2.4 A resolution

scientific article

Anomalous temperature factor behavior and crystal lattice mobility in cytochrome C'

scientific article

Anthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand binding

scientific article

Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis

scientific article

Cation binding to the integrin CD11b I domain and activation model assessment

scientific article

Caught before Released: Structural Mapping of the Reaction Trajectory for the Sofosbuvir Activating Enzyme, Human Histidine Triad Nucleotide Binding Protein 1 (hHint1).

scientific article

Conserved core substructures in the overlay of protein-ligand complexes.

scientific article

Crystal structure of yeast cytochrome c peroxidase refined at 1.7-A resolution

scientific article

Crystallization of the NAD-dependent malic enzyme from the parasitic nematode Ascaris suum

scientific article published on 01 July 1992

Crystallographic refinement of bovine pro-phospholipase A2 at 1.6 Å resolution ⬇️

scientific article published on October 1, 1991

Design, Synthesis, and Characterization of Sulfamide and Sulfamate Nucleotidomimetic Inhibitors of hHint1.

scientific article published on 15 June 2016

Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring ⬇️

scientific article published on April 10, 2012

Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.

scientific article published on 24 June 2015

Fragment-based identification of an inducible binding site on cell surface receptor CD44 for the design of protein-carbohydrate interaction inhibitors

scientific article

High-resolution crystal structures of alternate forms of the human CD44 hyaluronan-binding domain reveal a site for protein interaction.

scientific article

Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain.

scientific article published on 21 July 2017

Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice

scientific article published on 25 September 2019

Inhibition of Mycobacterium tuberculosis Transaminase BioA by Aryl Hydrazines and Hydrazides

scientific article

Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid.

scientific article published in May 2005

Kinetic and structural characterization of caspase-3 and caspase-8 inhibition by a novel class of irreversible inhibitors

scientific article

LORE: exploiting database of known structures.

scientific article published in January 1997

Lattice mobility and anomalous temperature factor behaviour in cytochrome c'

scientific article published on 01 June 1985

Ligand-induced expansion of the S1' site in the anthrax toxin lethal factor

scientific article

Mechanism-based Inactivation by Aromatization of the Transaminase BioA Involved in Biotin Biosynthesis in Mycobaterium tuberculosis

scientific article

Multiple conformations of amino acid residues in ribonuclease A

scientific article published on 01 December 1986

N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-D-aspartate receptor antagonists for the treatment of pain

scientific article published on 31 May 2007

Probing the S2' Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates

scientific article

Proteases of enhanced stability: characterization of a thermostable variant of subtilisin

scientific article published on 01 December 1986

Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation

scientific article published on 16 May 2017

Rational protein engineering in action: the first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus

scientific article

Recombinant human cytomegalovirus protease with a C-terminal (His)6 extension: purification, autocatalytic release of the mature enzyme, and biochemical characterization.

scientific article published in December 1998

Searching for likeness in a database of macromolecular complexes

scientific article published on 9 October 2013

Soybean trypsin inhibitor. An IL-1-like protein?

scientific article published on 01 June 1989

Structural Characterization of the Human Cytosolic Malate Dehydrogenase I

scientific article published on 28 December 2021

Structural characterization of human histidine triad nucleotide-binding protein 2, a member of the histidine triad superfamily

scientific article

Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity.

scientific article published on October 1998

Structure and Functional Characterization of Human Histidine Triad Nucleotide-Binding Protein 1 Mutations Associated with Inherited Axonal Neuropathy with Neuromyotonia

scientific article published on 19 May 2018

Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.

scientific article published on 22 June 2017

Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors.

scientific article published on November 1996

Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis

scientific article

Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.

scientific article

The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450

scientific article published in 1985

The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case

scientific article published on 01 November 1988

The structure of the TOG-like domain ofDrosophila melanogasterMast/Orbit

scientific article

The structure of the carboxyltransferase component of acetyl-coA carboxylase reveals a zinc-binding motif unique to the bacterial enzyme.

scientific article published in February 2006

Use of differential scanning fluorimetry to optimize the purification and crystallization of PLP-dependent enzymes ⬇️

scientific article published on April 21, 2012

Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors

scientific article

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