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List of works by Michela Varra

5-Hydroxymethyl-2'-deoxyuridine residues in the thrombin binding aptamer: investigating anticoagulant activity by making a tiny chemical modification

scientific article published on 11 September 2014

A BUNCH-OLIGONUCLEOTIDE FORMING STABLE MONOMOLECULAR QUADRUPLEX CONTAINING A T-TETRAD

scientific article published on 01 January 2005

A model for triple helix formation on human telomerase reverse transcriptase (hTERT) promoter and stabilization by specific interactions with the water soluble perylene derivative, DAPER.

scientific article published on 21 May 2007

A solid-phase approach to the synthesis of N-1-alkyl analogues of cyclic inosine-diphosphate-ribose (cIDPR)

A straightforward modification in the thrombin binding aptamer improving the stability, affinity to thrombin and nuclease resistance

scientific article published on 08 October 2014

Correction to New Anticancer Agents Mimicking Protein Recognition Motifs

scientific article published on 30 April 2015

Effect of gamma-hydroxypropano deoxyguanosine, the major acrolein-derived adduct, on monomolecular quadruplex structure of telomeric repeat d(TTAGGG)(4).

scientific article published in November 2004

Effects of acrolein on the quadruplex forming d(TTAGGG)4 telomeric repeat sequence

scientific article

Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue

scientific article published on 12 February 2014

Exploring the Photodynamic Properties of Two Antiproliferative Benzodiazopyrrole Derivatives

scientific article published on 13 February 2020

INTERACTION OF DISTAMYCIN A AND NETROPSIN WITH QUADRUPLEX AND DUPLEX STRUCTURES: A COMPARATIVE1H-NMR STUDY

Investigating the role of T7 and T12 residues on the biological properties of thrombin-binding aptamer: enhancement of anticoagulant activity by a single nucleobase modification.

scientific article

New anticancer agents mimicking protein recognition motifs

scientific article published on 19 August 2013

Oligonucleotides Containing an Acridine Group Covalently Bonded to the Nucleotide Flanking the 3′-3′ Phosphodiester Junction for Alternate Strand Triple Helix Formation ⬇️

scientific article published on May 1, 2003

Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue

scientific article published on 01 July 2014

Solid-Phase Synthesis of a New Diphosphate 5-Aminoimidazole-4-carboxamide Riboside (AICAR) Derivative and Studies toward Cyclic AICAR Diphosphate Ribose

scientific article published on 21 September 2011

Structural Studies and Biological Evaluation of T30695 Variants Modified with Single Chiral Glycerol-T Reveal the Importance of LEDGF/p75 for the Aptamer Anti-HIV-Integrase Activities

article

Structural study of four-stranded quadruplex structures containing 2'-deoxy-8-(propyn-1-yl)adenosine

scientific article published in March 2004

Superstructural self-assembly of the G-quadruplex structure formed by the homopurine strand in a DNA tract of human telomerase gene promoter

scientific article published on 2 May 2008

Synthesis and characterization of DNA quadruplexes containing T-tetrads formed by bunch-oligonucleotides

scientific article published on 01 February 2006

Synthesis and characterization of a bunchy oligonucleotide forming a monomolecular parallel quadruplex structure in solution

Synthesis and characterization of monomolecular DNA G-quadruplexes formed by tetra-end-linked oligonucleotides

scientific article published in July 2006

Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine

scientific article

Synthesis of 3′−3′-Linked Pyrimidine Oligonucleotides Containing an Acridine Moiety for Alternate Strand Triple Helix Formation

Synthesis of a Dibromoperylene Phosphoramidite Building Block and Its Incorporation at the 5′ End of a G-Quadruplex Forming Oligonucleotide: Spectroscopic Properties and Structural Studies of the Resulting Dibromoperylene Conjugate

scientific article published on 30 June 2011

Synthesis of a new N-9 ribityl analogue of cyclic inosine diphosphate ribose (cIDPR) as a mimic of cyclic ADP ribose (cADPR).

scientific article

Synthesis of a new ribose modified analogue of cyclic inosine diphosphate ribose

scientific article published in January 2007

Synthesis of new acadesine (AICA-riboside) analogues having acyclic D-ribityl or 4-hydroxybutyl chains in place of the ribose.

scientific article published on 6 August 2013

Synthesis of quadruplex-forming tetra-end-linked oligonucleotides: effects of the linker size on quadruplex topology and stability

scientific article published in June 2009

Synthesis, structural studies and biological properties of new TBA analogues containing an acyclic nucleotide.

scientific article

Targeting G-quadruplex structure in the human c-Kit promoter with short PNA sequences

scientific article

Unusual Chair-Like G-Quadruplex Structures: Heterochiral TBA Analogues Containing Inversion of Polarity Sites

scholarly article in Journal of Chemistry, 2015

Unusual monomolecular DNA quadruplex structures using bunch-oligonucleotides

scientific article published in January 2005

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