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List of works by Nisha Singh

A phase 2a randomised, double-blind, placebo-controlled, parallel-group, add-on clinical trial of ebselen (SPI-1005) as a novel treatment for mania or hypomania

scientific article published on 09 September 2020

A safe lithium mimetic for bipolar disorder

scientific article

Altered plasma glutathione levels in bipolar disorder indicates higher oxidative stress; a possible risk factor for illness onset despite normal brain-derived neurotrophic factor (BDNF) levels.

scientific article published on 27 January 2014

Assessing the feasibility of intranasal radiotracer administration for in brain PET imaging

scientific article published on 30 August 2018

Cloning, expression, purification, crystallization and X-ray analysis of inositol monophosphatase from Mus musculus and Homo sapiens

scientific article

Development of [18F]FAMTO: A novel fluorine-18 labelled positron emission tomography (PET) radiotracer for imaging CYP11B1 and CYP11B2 enzymes in adrenal glands

scientific article published on 09 November 2018

Ebselen has lithium-like effects on central 5-HT2A receptor function.

scientific article published on 27 February 2018

Effect of the Putative Lithium Mimetic Ebselen on Brain Myo-Inositol, Sleep, and Emotional Processing in Humans.

scientific article

Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla

scientific article

Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing

scientific article published on 02 June 2016

GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models

article

High-yielding F radiosynthesis of a novel oxytocin receptor tracer, a probe for nose-to-brain oxytocin uptake in vivo

scholarly article by Rhiannon Beard et al published 17 July 2018 in Chemical Communications

Investigating the effects of ebselen, a potential new lithium mimetic, on glutamate transmission

scientific article published on 13 February 2020

Kinetic modelling of [(11)C]PBR28 for 18 kDa translocator protein PET data: A validation study of vascular modelling in the brain using XBD173 and tissue analysis.

scientific article

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a second messenger in muscarinic receptor-induced contraction of guinea pig trachea.

scientific article

Plasma glutathione suggests oxidative stress is equally present in early- and late-onset bipolar disorder

scientific article published on 30 March 2018

Radiolabeling of [11C]FPS-ZM1, a receptor for advanced glycation end products-targeting positron emission tomography radiotracer, using a [11C]CO2-to-[11C]CO chemical conversion

scientific article published on 26 February 2020

Scaffold hopping with virtual screening from IP3 to a drug-like partial agonist of the inositol trisphosphate receptor.

scientific article