List of works - Michael White

A dual Golgi- and mitochondria-localised Ala25Ser precursor cystatin C: an additional tool for characterising intracellular mis-localisation leading to increased AMD susceptibility

scientific article published on 25 April 2006

A method of ‘speed coefficients’ for biochemical model reduction applied to the NF-κB system ⬇️

scientific article published on February 2015

A stochastic transcriptional switch model for single cell imaging data

scientific article

A systematic survey of the response of a model NF-κB signalling pathway to TNFα stimulation.

scientific article

Automated tracking of gene expression in individual cells and cell compartments.

scientific article

Automatic tracking of biological cells and compartments using particle filters and active contours

article published in 2006

Calcium-dependent regulation of the cell cycle via a novel MAPK--NF-kappaB pathway in Swiss 3T3 cells.

scientific article published on 23 August 2004

Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway.

scientific article

Cell cycle phase regulates glucocorticoid receptor function ⬇️

scientific article

Characterization of the ethanol-inducible alc gene-expression system in Arabidopsis thaliana.

scientific article published in October 2001

Distribution of acridine orange fluorescence in Plasmodium falciparum-infected erythrocytes and its implications for the evaluation of digestive vacuole pH.

scientific article

Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation.

scientific article published on 17 May 2016

Dynamic analysis of STAT6 signalling in living cells.

scientific article published on December 2002

Dynamic analysis of stochastic transcription cycles

scientific article

Dynamic resolution of acrosomal exocytosis in human sperm.

scientific article published on 3 June 2008

Edible Mushroom (Agaricus bisporus) Lectin, Which Reversibly Inhibits Epithelial Cell Proliferation, Blocks Nuclear Localization Sequence-dependent Nuclear Protein Import

scientific article published in Journal of Biological Chemistry

Evidence for an endogenous per1- and ICER-independent seasonal timer in the hamster pituitary gland.

scientific article published in May 2003

Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.

scientific article published on 6 April 2015

Heterogeneous regulation of individual lactotroph cells by photoperiod in the Syrian hamster (Mesocricetus auratus).

scientific article

Human prolactin gene promoter regulation by estrogen: convergence with tumor necrosis factor-alpha signaling.

scientific article published on 15 November 2007

In vivo localisation and stability of human Mcl-1 using green fluorescent protein (GFP) fusion proteins

scientific article published on 01 July 2000

Information management for high content live cell imaging

scientific article

Interactions among oscillatory pathways in NF-kappa B signaling

scientific article

Interactive segmentation of clustered cells via geodesic commute distance and constrained density weighted Nyström method.

scientific article published on December 2010

Measurement of single-cell dynamics.

scientific article

NF-kappaB signalling is inhibited by glucocorticoid receptor and STAT6 via distinct mechanisms

scientific article published on 06 May 2003

No barrier to diffusion between cell soma and neurite membranes in sympathetic neurons for a GPI-anchored glycoprotein.

scientific article published in October 2003

Oscillations in NF-kappaB signaling control the dynamics of gene expression

scientific article

Oscillations in transcription factor dynamics: a new way to control gene expression

scientific article published on 01 December 2004

Oscillatory control of signalling molecules ⬇️

scientific article published on September 17, 2010

P53 apoptosis mediator PERP: localization, function and caspase activation in uveal melanoma

scientific article published in August 2009

PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells.

scientific article

Peristalsis of airway smooth muscle is developmentally regulated and uncoupled from hypoplastic lung growth

scientific article published on 07 April 2006

Peritonitis activates transcription of the human prolactin locus in myeloid cells in a humanized transgenic rat model.

scientific article published on 11 April 2012

Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo

scientific article

Photoperiodic regulation of prolactin gene expression in the Syrian hamster by a pars tuberalis-derived factor.

scientific article

Population robustness arising from cellular heterogeneity

scientific article

Precursor cystatin C in cultured retinal pigment epithelium cells: evidence for processing through the secretory pathway

scientific article published in July 2001

Predicting the points of interaction of small molecules in the NF-κB pathway

scientific article

Pulsatile patterns of pituitary hormone gene expression change during development.

scientific article

Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription

scientific article

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

article

Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

scientific article published on 20 May 2015

Quantitative measurement of single cell dynamics.

scientific article

Real-time imaging of gene promoter activity using an adenoviral reporter construct demonstrates transcriptional dynamics in normal anterior pituitary cells.

scientific article published in July 2003

Real-time visualization of human prolactin alternate promoter usage in vivo using a double-transgenic rat model.

scientific article published on 15 January 2009

Serine 162, an Essential Residue for the Mitochondrial Localization, Stability and Anti-Apoptotic Function of Mcl-1 ⬇️

scientific article published on September 14, 2012

Single live-cell imaging for systems biology.

scientific article published on January 2008

Single-cell time-lapse imaging of the dynamic control of NF-kappaB signalling.

scientific article published in April 2007

Spatial and temporal information coding and noise in the NF-κB system.

scientific article

Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation

scientific article published on 04 October 2016

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

scientific article

Temperature regulates NF-κB dynamics and function through timing of A20 transcription.

scientific article published on 14 May 2018

The digestive food vacuole of the malaria parasite is a dynamic intracellular Ca2+ store.

scientific article

The molecular action of the novel insecticide, Pyridalyl.

scientific article published on 8 April 2011

The pH of the Plasmodium falciparum digestive vacuole: holy grail or dead-end trail?

scientific article

The prolactin gene: a paradigm of tissue-specific gene regulation with complex temporal transcription dynamics

scientific article

Tight control of hypoxia-inducible factor-α transient dynamics is essential for cell survival in hypoxia

scientific article published on 6 January 2014

Trafficking of osteonectin by retinal pigment epithelial cells: evidence for basolateral secretion.

scientific article published on 14 September 2006

Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells.

scientific article

Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappaB signaling.

scientific article published on 27 October 2005

Unexpected intracellular localization of the AMD-associated cystatin C variant.

scientific article published in November 2004

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

scientific article published on 21 September 2020

p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma.

scientific article

List of works by Michael White

A dual Golgi- and mitochondria-localised Ala25Ser precursor cystatin C: an additional tool for characterising intracellular mis-localisation leading to increased AMD susceptibility

A method of ‘speed coefficients’ for biochemical model reduction applied to the NF-κB system ⬇️

A stochastic transcriptional switch model for single cell imaging data

A systematic survey of the response of a model NF-κB signalling pathway to TNFα stimulation.

Automated tracking of gene expression in individual cells and cell compartments.

Automatic tracking of biological cells and compartments using particle filters and active contours

Calcium-dependent regulation of the cell cycle via a novel MAPK--NF-kappaB pathway in Swiss 3T3 cells.

Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway.

Cell cycle phase regulates glucocorticoid receptor function ⬇️

Characterization of the ethanol-inducible alc gene-expression system in Arabidopsis thaliana.

Distribution of acridine orange fluorescence in Plasmodium falciparum-infected erythrocytes and its implications for the evaluation of digestive vacuole pH.

Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation.

Dynamic analysis of STAT6 signalling in living cells.

Dynamic analysis of stochastic transcription cycles

Dynamic resolution of acrosomal exocytosis in human sperm.

Edible Mushroom (Agaricus bisporus) Lectin, Which Reversibly Inhibits Epithelial Cell Proliferation, Blocks Nuclear Localization Sequence-dependent Nuclear Protein Import

Evidence for an endogenous per1- and ICER-independent seasonal timer in the hamster pituitary gland.

Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.

Heterogeneous regulation of individual lactotroph cells by photoperiod in the Syrian hamster (Mesocricetus auratus).

Human prolactin gene promoter regulation by estrogen: convergence with tumor necrosis factor-alpha signaling.

In vivo localisation and stability of human Mcl-1 using green fluorescent protein (GFP) fusion proteins

Information management for high content live cell imaging

Interactions among oscillatory pathways in NF-kappa B signaling

Interactive segmentation of clustered cells via geodesic commute distance and constrained density weighted Nyström method.

Measurement of single-cell dynamics.

NF-kappaB signalling is inhibited by glucocorticoid receptor and STAT6 via distinct mechanisms

No barrier to diffusion between cell soma and neurite membranes in sympathetic neurons for a GPI-anchored glycoprotein.

Oscillations in NF-kappaB signaling control the dynamics of gene expression

Oscillations in transcription factor dynamics: a new way to control gene expression

Oscillatory control of signalling molecules ⬇️

P53 apoptosis mediator PERP: localization, function and caspase activation in uveal melanoma

PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells.

Peristalsis of airway smooth muscle is developmentally regulated and uncoupled from hypoplastic lung growth

Peritonitis activates transcription of the human prolactin locus in myeloid cells in a humanized transgenic rat model.

Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo

Photoperiodic regulation of prolactin gene expression in the Syrian hamster by a pars tuberalis-derived factor.

Population robustness arising from cellular heterogeneity

Precursor cystatin C in cultured retinal pigment epithelium cells: evidence for processing through the secretory pathway

Predicting the points of interaction of small molecules in the NF-κB pathway

Pulsatile patterns of pituitary hormone gene expression change during development.

Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription

Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation

Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer.

Quantitative measurement of single cell dynamics.

Real-time imaging of gene promoter activity using an adenoviral reporter construct demonstrates transcriptional dynamics in normal anterior pituitary cells.

Real-time visualization of human prolactin alternate promoter usage in vivo using a double-transgenic rat model.

Serine 162, an Essential Residue for the Mitochondrial Localization, Stability and Anti-Apoptotic Function of Mcl-1 ⬇️

Single live-cell imaging for systems biology.

Single-cell time-lapse imaging of the dynamic control of NF-kappaB signalling.

Spatial and temporal information coding and noise in the NF-κB system.

Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation

Systems biologists seek fuller integration of systems biology approaches in new cancer research programs

Temperature regulates NF-κB dynamics and function through timing of A20 transcription.

The digestive food vacuole of the malaria parasite is a dynamic intracellular Ca2+ store.

The molecular action of the novel insecticide, Pyridalyl.

The pH of the Plasmodium falciparum digestive vacuole: holy grail or dead-end trail?

The prolactin gene: a paradigm of tissue-specific gene regulation with complex temporal transcription dynamics

Tight control of hypoxia-inducible factor-α transient dynamics is essential for cell survival in hypoxia

Trafficking of osteonectin by retinal pigment epithelial cells: evidence for basolateral secretion.

Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells.

Tumor necrosis factor-alpha activates the human prolactin gene promoter via nuclear factor-kappaB signaling.

Unexpected intracellular localization of the AMD-associated cystatin C variant.

Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease

p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma.