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List of works by Annalisa Astolfi

45th annual meeting of the Italian Cancer Society. Bergamo, 9-12 November 2003.

scientific article

4th Pediatric Allergy and Asthma Meeting (PAAM)

scientific article (publication date: November 2016)

A distinct pediatric-type gastrointestinal stromal tumor in adults: potential role of succinate dehydrogenase subunit A mutations

scientific article published on 01 November 2011

A molecular portrait of gastrointestinal stromal tumors: an integrative analysis of gene expression profiling and high-resolution genomic copy number

scientific article published on 14 June 2010

A multi-DNA preventive vaccine for p53/Neu-driven cancer syndrome

scientific article published in May 2009

A novel specific signature of pediatric MOZ-CBP acute myeloid leukemia

scientific article published on 13 July 2010

Activity of sunitinib in extraskeletal myxoid chondrosarcoma

scientific article published on 02 April 2014

Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment.

scientific article published on 5 September 2016

An anti-apoptotic role for NGF receptors in human rhabdomyosarcoma

scientific article published in September 2001

An exploratory study by DMET array identifies a germline signature associated with imatinib response in gastrointestinal stromal tumor

scientific article published on 20 September 2018

An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer immunological prevention

scientific article published in December 2005

An overview on molecular biology of KIT/PDGFRA wild type (WT) gastrointestinal stromal tumours (GIST).

scientific article published on 05 July 2013

Analysis of all subunits, SDHA, SDHB, SDHC, SDHD, of the succinate dehydrogenase complex in KIT/PDGFRA wild-type GIST.

scientific article published on 24 April 2013

Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery

scientific article published on 27 November 2018

Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy

scientific article

Apc10.1: an ApcMin/+ intestinal cell line with retention of heterozygosity

scientific article published on March 2004

BCOR involvement in cancer

scientific article published on 31 May 2019

CBFA2T3-GLIS2 fusion transcript is a novel common feature in pediatric, cytogenetically normal AML, not restricted to FAB M7 subtype

scientific article published on 13 February 2013

CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis

scientific article

Characterization of pancreatic ductal adenocarcinoma using whole transcriptome sequencing and copy number analysis by single-nucleotide polymorphism array

scientific article published on 22 September 2015

Combined allogeneic tumor cell vaccination and systemic interleukin 12 prevents mammary carcinogenesis in HER-2/neu transgenic mice

scientific article

Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived Xenograft

scientific article published on 19 July 2019

Copy number gain of chromosome 3q is a recurrent event in patients with intraductal papillary mucinous neoplasm (IPMN) associated with disease progression

scientific article published on 22 August 2016

DHH-RHEBL1 fusion transcript: a novel recurrent feature in the new landscape of pediatric CBFA2T3-GLIS2-positive acute myeloid leukemia

scientific article

Development of rhabdomyosarcoma in HER-2/neu transgenic p53 mutant mice

article

Differential expression of neural markers in KIT and PDGFRA wild-type gastrointestinal stromal tumours

scientific article published in December 2011

Differential gene expression in classic giant cell tumours of bone: Tenascin C as biological risk factor for local relapses and metastases.

scientific article published in July 2010

Direct Antiviral Treatments for Hepatitis C Virus Have Off-Target Effects of Oncologic Relevance in Hepatocellular Carcinoma

scientific article published on 19 September 2020

Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia

scientific article published on 07 April 2009

Dystrophin deregulation is associated with tumor progression in KIT/PDGFRA mutant gastrointestinal stromal tumors

scientific article published on 9 August 2014

Effect of a low protein diet on chicken ceca microbiome and productive performances

scientific article published on 01 September 2019

Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP).

scientific article

Efficacy of and resistance to anti-IGF-1R therapies in Ewing's sarcoma is dependent on insulin receptor signaling

scientific article published on 31 January 2011

Endothelin-3 production by human rhabdomyosarcoma: a possible new marker with a paracrine role

scientific article published on 24 January 2006

Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial-Mesenchymal Transition-like Process and 22q Loss

article

Exosomes from CD99-deprived Ewing sarcoma cells reverse tumor malignancy by inhibiting cell migration and promoting neural differentiation

scientific article published on 17 June 2019

Expression of HER/erbB family of receptor tyrosine kinases and induction of differentiation by glial growth factor 2 in human rhabdomyosarcoma cells

scientific article published on 01 July 2000

Expression of IGF-1 receptor in KIT/PDGF receptor-α wild-type gastrointestinal stromal tumors with succinate dehydrogenase complex dysfunction

scientific article

F-FDG-PET/CT imaging in cardiac tumors: illustrative clinical cases and review of the literature

scientific article published on 30 August 2018

Gain of FGF4 is a frequent event in KIT/PDGFRA/SDH/RAS-P WT GIST

scientific article published on 16 April 2019

Gene expression analysis of immune-mediated arrest of tumorigenesis in a transgenic mouse model of HER-2/neu-positive basal-like mammary carcinoma

scientific article

Gene expression analysis uncovers similarity and differences among Burkitt lymphoma subtypes.

scientific article published on 18 January 2011

Gene expression profiling in colorectal cancer using microarray technologies: results and perspectives

scientific article published on 09 December 2008

Gene expression profiling of liver metastases from colorectal cancer as potential basis for treatment choice

scientific article published on 30 September 2008

Genetic heterogeneity in cholangiocarcinoma: a major challenge for targeted therapies

scientific article

Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST.

scientific article published on 27 January 2017

Genomic Database Analysis of Uterine Leiomyosarcoma Mutational Profile

scientific article published on 31 July 2020

Genomic Grade Index predicts postoperative clinical outcome of GIST.

scientific article

Genomic complexity and dynamics of clonal evolution in childhood acute myeloid leukemia studied with whole-exome sequencing

scientific article published on 22 July 2016

Good survival outcome of metastatic SDH-deficient gastrointestinal stromal tumors harboring SDHA mutations

scientific article published on 4 September 2014

HER/erbB receptors as therapeutic targets of immunotoxins in human rhabdomyosarcoma cells

scientific article published in July 2002

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

scientific article published on 6 April 2017

Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene

scientific article published on 21 January 2017

IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation.

scientific article

INPP4B overexpression and c-KIT downregulation in human achalasia.

scientific article published on 11 April 2018

Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute

scientific article

Identification of SRF-E2F1 fusion transcript in EWSR-negative myoepithelioma of the soft tissue

scientific article published on 17 May 2017

Identification of a cytogenetic and molecular subgroup of acute myeloid leukemias showing sensitivity to L-Asparaginase

scientific article published on 19 June 2017

Identification of an Actionable Mutation of KIT in a Case of Extraskeletal Myxoid Chondrosarcoma

scientific article published on 23 June 2018

Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma.

scientific article

Identification of new genes related to the myogenic differentiation arrest of human rhabdomyosarcoma cells

scientific article published on August 2001

Identification of the NUP98-PHF23 fusion gene in pediatric cytogenetically normal acute myeloid leukemia by whole-transcriptome sequencing

scientific article published on 12 June 2015

Immune microenvironment profiling of gastrointestinal stromal tumors (GIST) shows gene expression patterns associated to immune checkpoint inhibitors response

scientific article published on 04 June 2019

Immune prevention of mammary carcinogenesis in HER-2/neu transgenic mice: a microarray scenario

scientific article

Immunological prevention of a multigene cancer syndrome

scientific article

Immunoprevention of HER-2/neu transgenic mammary carcinoma through an interleukin 12-engineered allogeneic cell vaccine

scientific article published in June 2004

Immunoprevention of mammary carcinoma in HER-2/neu transgenic mice is IFN-gamma and B cell dependent

scientific article

Impact of Chemotherapy in the Adjuvant Setting of Early Stage Uterine Leiomyosarcoma: A Systematic Review and Updated Meta-Analysis

scientific article published on 14 July 2020

Impact of inflammatory cytokine gene polymorphisms on developing acute graft-versus-host disease in children undergoing allogeneic hematopoietic stem cell transplantation.

scientific article published on 20 April 2015

Impressive long-term disease stabilization by nilotinib in two pretreated patients with KIT/PDGFRA wild-type metastatic gastrointestinal stromal tumours.

scientific article

Inhibition of Methyltransferase DOT1L Sensitizes to Sorafenib Treatment AML Cells Irrespective of MLL-Rearrangements: A Novel Therapeutic Strategy for Pediatric AML

scientific article published on 20 July 2020

Inhibition of connective tissue growth factor (CTGF/CCN2) expression decreases the survival and myogenic differentiation of human rhabdomyosarcoma cells

scientific article published on March 2004

Insulin-like Growth Factor (IGF) system and gastrointestinal stromal tumours (GIST): present and future.

scientific article published on 16 October 2013

Insulin-like growth factor 1 receptor expression in wild-type GISTs: a potential novel therapeutic target.

scientific article published in December 2009

Integrated Molecular Characterization of Gastrointestinal Stromal Tumors (GIST) Harboring the Rare D842V Mutation in PDGFRA Gene

scientific article published on 4 March 2018

Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).

scientific article

Integrating miRNA and gene expression profiling analysis revealed regulatory networks in gastrointestinal stromal tumors.

scientific article published on 14 September 2016

Liquid biopsy in gastrointestinal stromal tumors: a novel approach

scientific article published on 14 August 2014

MYCN is a novel oncogenic target in pediatric T-cell acute lymphoblastic leukemia

scientific article published on January 2014

Management of patients with gastrointestinal stromal tumor in clinical practice in Italy: a critical "event tree model" analysis of decision-making processes and outcomes

scientific article published in March 2010

Mechanisms of resistance to a PI3K inhibitor in gastrointestinal stromal tumors: an omic approach to identify novel druggable targets

scientific article published on 05 July 2019

Microarray gene expression analysis of porcine skeletal muscle sampled at several post mortem time points.

scientific article published on 17 February 2011

Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) beyond KIT/PDGFRα genotype evaluated by next generation sequencing (NGS)

scientific article published on 2 November 2015

Molecular modelling evaluation of exon 18 His845_Asn848delinsPro PDGFRα mutation in a metastatic GIST patient responding to imatinib

scientific article published on 18 February 2019

Mutational burden of resectable pancreatic cancer, as determined by whole transcriptome and whole exome sequencing, predicts a poor prognosis.

scientific article published on 29 March 2018

N-3 PUFAs modulate global gene expression profile in cultured rat cardiomyocytes. Implications in cardiac hypertrophy and heart failure

article

NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas

scientific article published on 14 May 2019

Novel clinically relevant genes in GIST--letter

article

Novel intra-genic large deletions of CTNNB1 gene identified in WT desmoid-type fibromatosis

article

Nuclear phospholipase C beta1 (PLCbeta1) affects CD24 expression in murine erythroleukemia cells

scientific journal article

Opposing control of rhabdomyosarcoma growth and differentiation by myogenin and interleukin 4.

scientific article published in April 2009

Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1.

scientific article published on 17 February 2018

PDL1 expression is an independent prognostic factor in localized GIST.

scientific article published on 3 February 2015

Pediatric early T-cell precursor leukemia with NF1 deletion and high-sensitivity in vitro to tipifarnib.

scientific article published on 29 April 2010

Perfluoroalkyl substances in human milk: a first survey in Italy

article

Personalization of regorafenib treatment in metastatic gastrointestinal stromal tumours in real-life clinical practice

scientific article published on 19 December 2017

Personalized Medicine in Gastrointestinal Stromal Tumor (GIST): Clinical Implications of the Somatic and Germline DNA Analysis

scientific article

Phytosterol supplementation reduces metabolic activity and slows cell growth in cultured rat cardiomyocytes

scientific article published on 20 April 2011

Polymorphisms in DNA repair genes in gastrointestinal stromal tumours: susceptibility and correlation with tumour characteristics and clinical outcome.

scientific article published on 27 July 2016

Pooled genome-wide analysis to identify novel risk loci for pediatric allergic asthma

scientific article

Prevention of HER-2/neu transgenic mammary carcinoma by tamoxifen plus interleukin 12.

scientific article published in June 2003

Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin.

scientific article published on 15 May 2012

Progress in genomic technology: a new challenge for the palliative medicine?

scientific article published on 01 November 2010

Proteomic and PROTEOMEX profiling of mammary cancer progression in a HER-2/neu oncogene-driven animal model system.

scientific article published on November 2010

Radiotherapy in the management of gist: state of the art and new potential scenarios

scientific article published on 10 January 2017

SDHA loss-of-function mutations in KIT-PDGFRA wild-type gastrointestinal stromal tumors identified by massively parallel sequencing

scientific article

SDHC methylation in gastrointestinal stromal tumors (GIST): a case report

scientific article published on 28 September 2015

Skeletal Muscle Gene Expression in Long-Term Endurance and Resistance Trained Elderly

scientific article published on 02 June 2020

Successful multidisciplinary clinical approach and molecular characterization by whole transcriptome sequencing of a cardiac myxofibrosarcoma: A case report

scientific article published on 01 October 2019

Synergistic Cytotoxic Effect of L-Asparaginase Combined with Decitabine as a Demethylating Agent in Pediatric T-ALL, with Specific Epigenetic Signature.

scientific article published on 27 November 2016

TIS21/BTG2/PC3 and cyclin D1 are key determinants of nuclear diacylglycerol kinase-zeta-dependent cell cycle arrest

scientific article published on 20 January 2009

Targeted Deep Sequencing Uncovers Cryptic KIT Mutations in KIT/PDGFRA/SDH/RAS-P Wild-Type GIST

scientific article published on 22 April 2020

The Emerging Role of the FGF/FGFR Pathway in Gastrointestinal Stromal Tumor

scientific article published on 07 May 2020

The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs).

scientific article

The expression of ccn3(nov) gene in musculoskeletal tumors

scientific article published on March 2002

The metastatic ability of Ewing's sarcoma cells is modulated by stem cell factor and by its receptor c-kit

scientific article published in December 2000

The molecular mechanisms responsible for resistance to ET-743 (Trabectidin; Yondelis) in the Ewing's sarcoma cell line, TC-71.

scientific article published on December 2005

The progressive fragmentation of the KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GIST)

scientific article

Therapy of lung metastases through combined vaccination with carcinoma cells engineered to release IL-13 and IFN-gamma

scientific article

Transient abnormal myelopoiesis in a phenotypically normal newborn with polyclonal trisomy 21

scientific article published on 26 April 2014

Trisomy 11 with MLL-PTD in a case of infant AML M0

scientific article published on 26 July 2007

Whole Exome Sequencing Uncovers Germline Variants of Cancer-Related Genes in Sporadic Pheochromocytoma

article

Whole exome sequencing (WES) on formalin-fixed, paraffin-embedded (FFPE) tumor tissue in gastrointestinal stromal tumors (GIST).

scientific article published on 3 November 2015

Whole transcriptome sequencing identifies BCOR internal tandem duplication as a common feature of clear cell sarcoma of the kidney

scientific article published on 22 October 2015

Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del(5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts

scientific article published on 27 March 2014

miRNA profiling in gastrointestinal stromal tumors: implication as diagnostic and prognostic markers

scientific article published on 08 October 2015

miRNA–221 and miRNA–483–3p Dysregulation in Esophageal Adenocarcinoma

scientific article published in 2024

p185(neu) protein is required for tumor and anchorage-independent growth, not for cell proliferation of transgenic mammary carcinoma

scientific article published in 2000

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