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List of works by Manfred Auer

A Wide-Field Fluorescence Microscope Extension for Ultrafast Screening of One-Bead One-Compound Libraries Using a Spectral Image Subtraction Approach

scientific article

A direct way of redox sensing

scientific article published on 01 January 2011

A general synthetic route to isomerically pure functionalized rhodamine dyes.

scientific article published on 14 October 2015

A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference

scientific article published on 5 June 2014

A magnetic bead-based ligand binding assay to facilitate human kynurenine 3-monooxygenase drug discovery

scientific article

A novel splice variant of the transcription factor Nrf1 interacts with the TNFalpha promoter and stimulates transcription.

scientific article published on May 1998

A two-channel detection method for autofluorescence correction and efficient on-bead screening of one-bead one-compound combinatorial libraries using the COPAS fluorescence activated bead sorting system.

scientific article

Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection

scientific article

Analysis of Protein−Small Molecule Interactions by Microscale Equilibrium Dialysis and Its Application As a Secondary Confirmation Method for on-Bead Screening

scientific article published on September 13, 2010

Bacterial expression of human kynurenine 3-monooxygenase: solubility, activity, purification

scientific article published on 04 December 2013

Beyond dimerization: a membrane-dependent activation model for interleukin-4 receptor-mediated signalling.

scientific article published on 6 December 2006

Biochemical characterization of binding of multiple HIV-1 Rev monomeric proteins to the Rev responsive element.

scientific article published in October 1993

CSBB-ConeExclusion, adapting structure based solution virtual screening to libraries on solid support.

scientific article

Characterization of human immunodeficiency virus-1 (HIV-1) rev by (time-resolved) fluorescence spectroscopy

scientific article published in December 1994

Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion

scientific article published on 24 February 2022

Complementary Benzophenone Cross-Linking/Mass Spectrometry Photochemistry.

scientific article published on 21 April 2017

Confocal fluorescence detection expanded to UV excitation: the first continuous fluorimetric assay of human steroid sulfatase in nanoliter volume

scientific article published in February 2004

Confocal nanoscanning, bead picking (CONA): PickoScreen microscopes for automated and quantitative screening of one-bead one-compound libraries

scientific article published in September 2009

Crystallization and preliminary X-ray crystallographic study of interleukin-8.

scientific article published in June 1990

Detecting drug-target binding in cells using fluorescence-activated cell sorting coupled with mass spectrometry analysis

scientific article published on 13 September 2017

Diclofenac Identified as a Kynurenine 3-Monooxygenase Binder and Inhibitor by Molecular Similarity Techniques

scientific article published on 02 March 2018

Diphenylhexatriene-phosphatidylcholine fluorescence in POPC vesicles: Comparison of the exponential-series and the maximum-entropy methods

scientific article published on 01 December 1994

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

scientific article

Effects of phosphatidylinositol-3-kinase inhibitors on degranulation and gene induction in allergically triggered mouse mast cells.

scientific article published on April 1997

Evaluation of the metal ion requirement of the human deoxyhypusine hydroxylase from HeLa cells using a novel enzyme assay

scientific article published on 01 February 1996

Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D

scientific article published on 24 January 2020

Facile Synthesis of a Next Generation Safety-Catch Acid-Labile Linker, SCAL-2, Suitable for Solid-Phase Synthesis, On-Support Display and for Post-Synthesis Tagging.

scientific article published on 16 August 2017

Fluorescent Fingerprinting of Molecular Recognition Landscapes J.J.L. thanks Wolfgang Rettig (Humboldt University) for his generosity during the preparation of this manuscript and the Uebbing Foundation for support. M.A. thanks Jan E. de Vries for c

scientific article published in May 2001

Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses

scientific article published on 25 September 2017

HTS: understanding the physiology of life

scientific article published on 01 September 2001

Helix-loop-helix motif in HIV-1 Rev

scientific article published on 01 March 1994

High Level Expression and Structural Characterisation of Herpes Simplex Virus Type I Transcriptional Activator VP16 (α-transInducing Factor)

scientific article published on October 9, 1998

High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.

scientific article published on 17 January 2014

Identification and X-ray co-crystal structure of a small-molecule activator of LFA-1-ICAM-1 binding

scientific article

Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries.

scientific article

Intensity-independent fluorometric detection of cellular nitric oxide release

scientific article published on May 1997

Isolation and structural characterization of different isoforms of the hypusine-containing protein eIF-5A from HeLa cells.

scientific article

MRlogP: Transfer Learning Enables Accurate logP Prediction Using Small Experimental Training Datasets

scientific article published on 15 November 2021

Multi-photon excitation of intrinsic protein fluorescence and its application to pharmaceutical drug screening

scientific article published on 01 April 2005

New fluorogenic substrate for the first continuous steroid sulfatase assay

scientific article published on 01 May 2000

Novel 1:1 labeling and purification process for C-terminal thioester and single cysteine recombinant proteins using generic peptidic toolbox reagents

scientific article

Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing

scientific article published on 29 November 2018

On-bead screens sample narrower affinity ranges of protein-ligand interactions compared to equivalent solution assays.

scientific article

Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback

scientific article

Perturbation of the carboxy terminus of HIV-1 Rev affects multimerization on the Rev responsive element

scientific article published on 01 August 1993

Proximity-dependent initiation of hybridization chain reaction

scientific article published on 12 June 2015

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries

scientific article published on 23 February 2018

Purification, crystallization and preliminary X-ray diffraction analysis of recombinant human neutrophil-activating peptide 2 (rhNAP-2).

scientific article

Quantitative Microdialysis: Experimental Protocol and Software for Small Molecule Protein Affinity Determination and for Exclusion of Compounds with Poor Physicochemical Properties

scientific article published on 30 July 2020

Rapid Synthesis of 2' and 3' Fluorinated Nucleotides and Their Use in 19F-NMR-Spectroscopy of Nucleotide-Binding Enzymes

Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods.

scientific article

Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

scientific article published on 10 August 2018

Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

Seamless Insert-Plasmid Assembly at High Efficiency and Low Cost.

scientific article

Single bead labeling method for combining confocal fluorescence on-bead screening and solution validation of tagged one-bead one-compound libraries

scientific article published in July 2009

Structural Dynamics of HIV-1 Rev and Its Complexes with RRE and 5S RNA

scientific article published on February 17, 1998

Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity

scientific article

Structure of the P-type ATPases

article

Synthesis and Biological Applications of 2',3'-Dideoxynucleoside-5'-O-(α-thio)Triphosphates

Temperature inducible beta-sheet structure in the transactivation domains of retroviral regulatory proteins of the Rev family

scientific article published on 01 November 1999

The amino terminal domain of HIV-1 Rev is required for discrimination of the RRE from nonspecific RNA.

scientific article

The polypeptide chain of eukaryotic initiation factor 5A occurs in two distinct conformations in the absence of the hypusine modification

scientific article published on 01 November 1995

The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei

scientific article

Three-dimensional map of the plasma membrane H+-ATPase in the open conformation.

scientific article

Time-resolved fluorescence anisotropy of HIV-1 protease inhibitor complexes correlates with inhibitory activity

scientific article published on 01 March 1998

Towards mimicking short linear peptide motifs: identification of new mixed α,β-peptidomimetic ligands for SLAM-Associated Protein (SAP) by confocal on-bead screening

scientific article

Transcytosis and Surface Presentation of IL-8 by Venular Endothelial Cells

scientific article published on 01 October 1997

UFSRAT: Ultra-fast Shape Recognition with Atom Types--the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11βHSD1

scientific article

X-ray structure and conformational dynamics of the HIV-1 protease in complex with the inhibitor SDZ283-910: agreement of time-resolved spectroscopy and molecular dynamics simulations

scientific article

mRNA openers and closers: modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure.

scientific article

α-Synuclein-Confocal Nanoscanning (ASYN-CONA), a Bead-Based Assay for Detecting Early-Stage α-Synuclein Aggregation

scientific article published on 18 April 2019