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List of works by Kelvin Y Kwan

Activation of CHK1 in Supporting Cells Indirectly Promotes Hair Cell Survival

scientific article

Activation of PI3K signaling prevents aminoglycoside-induced hair cell death in the murine cochlea

scientific article published on 03 May 2016

Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons

Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons

An ion channel essential for sensing chemical damage.

scientific article

C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells

scientific article

Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta

scholarly article

Development of autoimmunity in mice lacking DNA topoisomerase 3beta

scholarly article

GATC motifs may alter the conformation of DNA depending on sequence context and N6-adenine methylation status: possible implications for DNA-protein recognition.

scientific article published in June 1998

Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain

scientific article published on 27 March 2020

Induction of stem-cell-derived functional neurons by NanoScript-based gene repression

scientific article published on 20 August 2015

Infertility and aneuploidy in mice lacking a type IA DNA topoisomerase III beta

scientific journal article

Initiating Differentiation in Immortalized Multipotent Otic Progenitor Cells

scientific article published on 2 January 2016

NEUROG1 Regulates CDK2 to Promote Proliferation in Otic Progenitors.

scientific article published on 11 October 2017

SHIELD: an integrative gene expression database for inner ear research.

scientific article published on 24 July 2015

SNX-1 and RME-8 oppose the assembly of HGRS-1/ESCRT-0 degradative microdomains on endosomes

scientific article published on 04 January 2017

Sensory Neuron-Specific Deletion of TRPA1 Results in Mechanical Cutaneous Sensory Deficits

scientific article published on January 2017

Single-Cell Transcriptome Analysis of Developing and Regenerating Spiral Ganglion Neurons.

scientific article published on 4 August 2016

Single-Cell Transcriptome Analysis of Neural Stem Cells.

scientific article

TRPA1 acts as a cold sensor in vitro and in vivo

scientific article

TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3

scientific article published on December 11, 2011

TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells

scientific journal article

TRPA1 modulates mechanotransduction in cutaneous sensory neurons.

scientific article published on April 2009

The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli

scientific article published on 24 July 2009

Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development

scientific article published on 07 December 2016

Transcriptome-wide comparison of the impact of Atoh1 and miR-183 family on pluripotent stem cells and multipotent otic progenitor cells.

scientific article published on 7 July 2017

Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing

scientific article published on 25 July 2016

Unwinding of the Escherichia coli origin of replication (oriC) can occur in the absence of initiation proteins but is stabilized by DnaA and histone-like proteins IHF or HU.

scientific article published in January 1998

Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA

scientific article published on 16 February 2022