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List of works by Craig A Harrison

2-Phenyl and 2-heterocyclic-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridines as inhibitors of TGF-β1 and activin A signalling.

scientific article published on 30 December 2010

A Novel, More Efficient Approach to Generate Bioactive Inhibins

scientific article published on 07 April 2016

A common biosynthetic pathway governs the dimerization and secretion of inhibin and related transforming growth factor beta (TGFbeta) ligands

scientific article published on 3 February 2009

Aberrant GDF9 expression and activation are associated with common human ovarian disorders.

scientific article

Activation of latent human GDF9 by a single residue change (Gly 391 Arg) in the mature domain

scientific article published on 10 January 2012

Activin Signaling Regulates Sertoli Cell Differentiation and Function ⬇️

scientific article published on November 1, 2012

Activin-A binds follistatin and type II receptors through overlapping binding sites: generation of mutants with isolated binding activities

scientific article published on 9 March 2006

Activins and inhibins and their signaling.

scientific article published in December 2004

BMP15 Mutations Associated With Primary Ovarian Insufficiency Reduce Expression, Activity, or Synergy With GDF9.

scientific article published in March 2017

Biological activity and in vivo half-life of pro-activin A in male rats.

scientific article published on 11 December 2015

Characterization of a mutant recombinant S100 protein using electrospray ionization mass spectrometry

scientific article published on 01 January 1997

Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

scientific article

Development of novel activin-targeted therapeutics

scientific article

Differential Effects of IL6 and Activin A in the Development of Cancer-Associated Cachexia.

scientific article published on 21 June 2016

Elevated expression of activins promotes muscle wasting and cachexia.

scientific article published on 30 December 2013

Expression of nodal signalling components in cycling human endometrium and in endometrial cancer

scientific article published on 29 October 2009

Extra-ovarian expression and activity of growth differentiation factor 9.

scientific article

Feedback regulation by inhibins A and B of the pituitary secretion of follicle-stimulating hormone

scientific article published on January 2011

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin ⬇️

scientific article published on June 18, 2012

Functional analysis of the human inhibin alpha subunit variant A257T and its potential role in premature ovarian failure.

scientific article

Generation of a specific activin antagonist by modification of the activin A propeptide.

scientific article published on 12 July 2011

Germline mutations of inhibins in early-onset ovarian epithelial tumors

scientific article

Growth differentiation factor 9:bone morphogenetic protein 15 (GDF9:BMP15) synergism and protein heterodimerization.

scientific article published on 6 May 2013

Hormonal regulation of sertoli cell micro-RNAs at spermiation

scientific article published on 15 February 2011

HtrA3 Is Downregulated in Cancer Cell Lines and Significantly Reduced in Primary Serous and Granulosa Cell Ovarian Tumors.

scientific article published on February 2013

Identification of distinct inhibin and transforming growth factor beta-binding sites on betaglycan: functional separation of betaglycan co-receptor actions.

scientific article published on 18 April 2006

Identification of protein binding partners of ALK-5 kinase inhibitors

scientific article

Immunodetection of the murine chemotactic protein CP-10 in bleomycin-induced pulmonary injury.

scientific article

Induction of the S100 chemotactic protein, CP-10, in murine microvascular endothelial cells by proinflammatory stimuli

scientific article published on 01 December 1997

Inhibin B is a more potent suppressor of rat follicle-stimulating hormone release than inhibin a in vitro and in vivo.

scientific article

Inhibin Biosynthesis and Activity Are Limited by a Prodomain-Derived Peptide

scientific article published on 11 May 2015

Inhibin binding sites and proteins in pituitary, gonadal, adrenal and bone cells.

scientific article

Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy

scientific article published on 01 July 2018

Interleukin 11 and activin A synergise to regulate progesterone-induced but not cAMP-induced decidualization.

scientific article published on 13 January 2010

Lentiviral transduction of rat Sertoli cells as a means to modify gene expression.

scientific article

Loss of betaglycan contributes to the malignant properties of human granulosa tumor cells.

scientific article

Molecular characterization of latent GDF8 reveals mechanisms of activation.

scientific article published on 18 January 2018

Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling

scientific article published on 14 June 2017

Mutational analysis of betaglycan/TGF-betaRIII in premature ovarian failure

scientific article published on 02 November 2006

New insights into the mechanisms of activin action and inhibition ⬇️

scientific article published on 08 July 2011

Oxidation regulates the inflammatory properties of the murine S100 protein S100A8

scientific article published on 01 March 1999

Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands

scientific article published on 24 August 2011

Retinoic acid promotes Sertoli cell differentiation and antagonises activin-induced proliferation.

scientific article published on 2 July 2013

Selection of internal control genes for analysis of gene expression in normal and diseased human dermal fibroblasts using quantitative real-time PCR.

scientific article published in June 2016

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice.

scientific article published on July 2016

Species differences in the expression and activity of bone morphogenetic protein 15.

scientific article

Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease

scientific article

Structural basis for potency differences between GDF8 and GDF11.

scientific article

The Synthesis and Secretion of Inhibins

scientific article published on January 1, 2011

The TGF-β Signalling Network in Muscle Development, Adaptation and Disease.

scientific article published on January 2016

The activin A antagonist follistatin inhibits asthmatic airway remodelling

scientific article

The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.

scientific article published on 20 February 2017

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass.

scientific article published on 21 October 2013

Two distinct regions of latency-associated peptide coordinate stability of the latent transforming growth factor-beta1 complex

scientific article

Use of detergent-based buffers allows detection of precursor inhibin forms in an immunoassay format.

scientific article published on 30 July 2013

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