List of works - Michele Longo

A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells.

scientific article published on 30 May 2017

Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications ⬇️

scientific article published on 13 May 2019

Bisphenol-A impairs insulin action and up-regulates inflammatory pathways in human subcutaneous adipocytes and 3T3-L1 cells

scientific article (publication date: 2013)

Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells.

scientific article published on 29 March 2018

Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity.

scientific article published on 24 October 2017

Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells.

scientific article

Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle

scientific article published on 9 October 2015

Hepatocyte nuclear factor (HNF)-4alpha-driven epigenetic silencing of the human PED gene.

scientific article published on 16 April 2010

High-fat diet unveils an enhancer element at the Ped/Pea-15 gene responsible for epigenetic memory in skeletal muscle

scientific article published on 19 June 2018

Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet

scientific article published on 16 March 2016

IL-3 synergises with basophil-derived IL-4 and IL-13 to promote the alternative activation of human monocytes.

scientific article published on 28 April 2015

Low-Dose Bisphenol-A Impairs Adipogenesis and Generates Dysfunctional 3T3-L1 Adipocytes

scientific article

Low-dose Bisphenol-A Promotes Epigenetic Changes at Pparγ Promoter in Adipose Precursor Cells

scientific article published on 13 November 2020

Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells

scientific article published on 18 October 2018

Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo.

scientific article

Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage.

scientific article published on 18 January 2017

Nutritional Factors, DNA Methylation, and Risk of Type 2 Diabetes and Obesity: Perspectives and Challenges

scientific article published on 19 June 2019

PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice.

scientific article

Pathologic endoplasmic reticulum stress induced by glucotoxic insults inhibits adipocyte differentiation and induces an inflammatory phenotype.

scientific article published on 29 February 2016

Peroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1

scientific article

Personalized medicine and type 2 diabetes: lesson from epigenetics.

scientific article published on April 2014

Prep1, A Homeodomain Transcription Factor Involved in Glucose and Lipid Metabolism

scientific article published on 28 June 2018

Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity.

scientific article published on 07 March 2017

The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells.

scientific article published on 15 November 2016

Understanding type 2 diabetes: from genetics to epigenetics

scientific article published on 05 April 2015

miR-214-Dependent Increase of PHLPP2 Levels Mediates the Impairment of Insulin-Stimulated Akt Activation in Mouse Aortic Endothelial Cells Exposed to Methylglyoxal.

scientific article published on 9 February 2018

List of works by Michele Longo

A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells.

Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications ⬇️

Bisphenol-A impairs insulin action and up-regulates inflammatory pathways in human subcutaneous adipocytes and 3T3-L1 cells

Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells.

Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity.

Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells.

Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle

Hepatocyte nuclear factor (HNF)-4alpha-driven epigenetic silencing of the human PED gene.

High-fat diet unveils an enhancer element at the Ped/Pea-15 gene responsible for epigenetic memory in skeletal muscle

Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet

IL-3 synergises with basophil-derived IL-4 and IL-13 to promote the alternative activation of human monocytes.

Low-Dose Bisphenol-A Impairs Adipogenesis and Generates Dysfunctional 3T3-L1 Adipocytes

Low-dose Bisphenol-A Promotes Epigenetic Changes at Pparγ Promoter in Adipose Precursor Cells

Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells

Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo.

Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage.

Nutritional Factors, DNA Methylation, and Risk of Type 2 Diabetes and Obesity: Perspectives and Challenges

PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice.

Pathologic endoplasmic reticulum stress induced by glucotoxic insults inhibits adipocyte differentiation and induces an inflammatory phenotype.

Peroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1

Personalized medicine and type 2 diabetes: lesson from epigenetics.

Prep1, A Homeodomain Transcription Factor Involved in Glucose and Lipid Metabolism

Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity.

The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells.

Understanding type 2 diabetes: from genetics to epigenetics

miR-214-Dependent Increase of PHLPP2 Levels Mediates the Impairment of Insulin-Stimulated Akt Activation in Mouse Aortic Endothelial Cells Exposed to Methylglyoxal.