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List of works by Jianjun Cheng

5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice.

scientific article published on 15 March 2017

A Cell-penetrating Helical Polymer For siRNA Delivery to Mammalian Cells ⬇️

scientific article published on May 29, 2012

Azido-galactose outperforms azido-mannose for metabolic labeling and targeting of hepatocellular carcinoma

scientific article published on 01 August 2019

Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure–Functional Selectivity Relationships (SFSRs) and Therapeutic Potential

article

Cancer cell-targeted cisplatin prodrug delivery <i>in vivo via</i> metabolic labeling and bioorthogonal click reaction

scientific article published on 22 December 2020

Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis

scientific article published in 2021

Chain‐Shattering Polymeric Therapeutics with On‐Demand Drug‐Release Capability ⬇️

scientific article published on 06 May 2013

Design and Discovery of Functionally Selective Serotonin 2C (5-HT2C) Receptor Agonists

scientific article

Design and Synthesis of (2-(5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)cyclopropyl)methanamine as a Selective Serotonin 2C Agonist

scientific article published on June 2015

Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands

scientific article published on 13 April 2020

Dimeric Prodrug Self-Delivery Nanoparticles with Enhanced Drug Loading and Bioreduction Responsiveness for Targeted Cancer Therapy

scientific article published on 09 November 2018

Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications.

scientific article

Drug-Initiated Ring-Opening Polymerization of O-Carboxyanhydrides for the Preparation of Anticancer Drug–Poly(O-carboxyanhydride) Nanoconjugates ⬇️

scientific article published on February 27, 2013

Dynamic Ureas with Fast and pH-Independent Hydrolytic Kinetics.

scientific article published on 6 April 2018

Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models.

scientific article published on 24 December 2015

Haloperidol bound D2 dopamine receptor structure inspired the discovery of subtype selective ligands

scientific article published on 26 February 2020

High Drug Loading and Sub-Quantitative Loading Efficiency of Polymeric Micelles Driven by Donor-Receptor Coordination Interactions.

scientific article published on 13 January 2018

Induction of a higher-ordered architecture in glatiramer acetate improves its biological efficiency in an animal model of multiple sclerosis

scientific article published on 03 August 2020

Light‐Responsive Helical Polypeptides Capable of Reducing Toxicity and Unpacking DNA: Toward Nonviral Gene Delivery ⬇️

scientific article published on July 5, 2013

Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

scientific article published on 23 February 2018

Momilactone and Related Diterpenoids as Potential Agricultural Chemicals.

scientific article

Nanoscale liposomal formulation of a SYK P-site inhibitor against B-precursor leukemia ⬇️

scientific article published on April 8, 2013

Near IR heptamethine cyanine dye-mediated cancer imaging

scientific article

Non‐Viral Gene Delivery via Membrane‐Penetrating, Mannose‐Targeting Supramolecular Self‐Assembled Nanocomplexes ⬇️

scientific article published on February 18, 2013

Novel Liposomal Azido Mannosamine Lipids on Metabolic Cell Labeling and Imaging via Cu-Free Click Chemistry

scientific article published on 16 August 2019

Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents

scientific article published on 10 February 2015

Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties

scientific article published on 19 March 2019

Preclinical efficacy of the camptothecin-polymer conjugate IT-101 in multiple cancer models

scientific article

Proximity-Induced Cooperative Polymerization in "Hinged" Helical Polypeptides

scientific article published on 24 May 2019

Reactive and Bioactive Cationic α‐Helical Polypeptide Template for Nonviral Gene Delivery ⬇️

scientific article published on December 7, 2011

Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery ⬇️

scientific article published on December 31, 2012

Revisiting the Helical Cooperativity of Synthetic Polypeptides in Solution.

scientific article

Size-Dependent Tumor Penetration and in Vivo Efficacy of Monodisperse Drug–Silica Nanoconjugates ⬇️

scientific article published on February 12, 2013

Supramolecular Assembly of Comb-like Macromolecules Induced by Chemical Reactions that Modulate the Macromolecular Interactions In Situ.

scientific article published on 4 August 2017

Synthesis of Water-Soluble Poly(α-hydroxy acids) from Living Ring-Opening Polymerization of O-Benzyl-l-serine Carboxyanhydrides ⬇️

scientific article published on April 17, 2012

The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands

scientific article published on 23 May 2022

Tumor Immunotherapy Using A2A Adenosine Receptor Antagonists

scientific article published on 08 September 2020

Water-Soluble Polypeptides with Elongated, Charged Side Chains Adopt Ultrastable Helical Conformations ⬇️

scientific article published on September 13, 2011

We Need 2C but Not 2B: Developing Serotonin 2C (5-HT2C) Receptor Agonists for the Treatment of CNS Disorders.

scientific article published on 28 October 2015

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