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List of works by Luciano Cascione

A Polysome-Based microRNA Screen Identifies miR-24-3p as a Novel Promigratory miRNA in Mesothelioma

scientific article published on 02 August 2018

A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model ⬇️

scientific article published on April 16, 2013

Androgen receptor status is a prognostic marker in non-basal triple negative breast cancers and determines novel therapeutic options

scientific article

BET bromodomain inhibitor birabresib in mantle cell lymphoma: in vivo activity and identification of novel combinations to overcome adaptive resistance

scientific article published on 26 September 2018

Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma

scientific article published on 03 August 2018

Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma.

scientific article published on August 2016

Characterisation of the immune-related transcriptome in resected biliary tract cancers

scientific article published on 5 October 2017

Circulating miRNA markers show promise as new prognosticators for multiple myeloma

scientific article

Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.

scientific article published on 8 March 2016

Copanlisib synergizes with conventional and targeted agents including venetoclax in B- and T-cell lymphoma models

scientific article published on 01 March 2020

Correction to: cuRnet: an R package for graph traversing on GPU

scholarly article by Vincenzo Bonnici published in November 2018

Correction: In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation

scientific article

DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features

scientific article published on 22 January 2015

DNA methylation profiling reveals common signatures of tumorigenesis and defines epigenetic prognostic subtypes of canine Diffuse Large B-cell Lymphoma.

scientific article published on 14 September 2017

Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism

scientific article

Diffuse large B cell lymphoma cell of origin by digital expression profiling in the REAL07 Phase 1-2 study

scientific article published on 24 July 2017

EGFR and MET receptor tyrosine kinase-altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers

scientific article

Elucidating the role of microRNAs in cancer through data mining techniques

scientific article

Genome-wide promoter methylation of hairy cell leukemia

scientific article published on 01 February 2019

HDAC inhibitor AR-42 decreases CD44 expression and sensitizes myeloma cells to lenalidomide

scientific article published on 25 September 2015

IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies

scientific article published on 19 November 2018

In vitro demonstration of synergism with pixantrone combined with targeted agents in lymphomas

scientific article published on 19 December 2018

In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation

scientific article published on 22 April 2013

Integrated microRNA and mRNA signatures associated with survival in triple negative breast cancer

scientific article

Integration of Omics Data to Identify Cancer-Related MicroRNA

scientific article published on 01 January 2019

Let-7c down-regulation in Helicobacter pylori-related gastric carcinogenesis

scientific article published on 17 December 2015

Long Non-Coding RNAs as Molecular Signatures for Canine B-Cell Lymphoma Characterization

scientific article published on 19 September 2019

MIDClass: microarray data classification by association rules and gene expression intervals

scientific article

MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma

scientific article published on 4 November 2017

Metabolic heterogeneity on baseline 18FDG-PET/CT scan is a predictor of outcome in primary mediastinal B-cell lymphoma.

scientific article published on 2 May 2018

MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non–small-cell lung cancer through BIM down-regulation ⬇️

scientific article published on September 24, 2012

MicroRNA 193b-3p as a predictive biomarker of chronic kidney disease in patients undergoing radical nephrectomy for renal cell carcinoma.

scientific article

MicroRNA Profiling of Salivary Duct Carcinoma Versus Her2/Neu Overexpressing Breast Carcinoma Identify miR-10a as a Putative Breast Related Oncogene

scientific article published on 26 September 2018

MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer

scientific article published on April 2014

Mutational landscape of canine B-cell lymphoma profiled at single nucleotide resolution by RNA-seq

scientific article published on 24 April 2019

Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.

scientific article published on 14 August 2017

Outcome of patients older than 80 years with diffuse large B-cell lymphoma (DLBCL) treated with "standard" immunochemotherapy: A large retrospective study from 4 institutions.

scientific article published on 16 June 2017

PQR309 Is a Novel Dual PI3K/mTOR Inhibitor with Preclinical Antitumor Activity in Lymphomas as a Single Agent and in Combination Therapy.

scientific article

Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma.

scientific article published on 27 June 2017

Prognostic Models Integrating Quantitative Parameters from Baseline and Interim Positron Emission Computed Tomography in Patients with Diffuse Large B-Cell Lymphoma: Post-Hoc Analysis from the SAKK38/07 Clinical Trial

scientific article published on 18 September 2020

Programmed cell death 4 (PDCD4) as a novel prognostic marker for papillary thyroid carcinoma

scientific article published on 20 August 2019

Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation

scientific article (publication date: 25 March 2014)

Regulation of acute graft-versus-host disease by microRNA-155.

scientific article

Retracted: Gradual Rarefaction of Hematopoietic Precursors and Atrophy in a Depleted microRNA 29a, b and c Environment

retracted article

Role of ETS1 in the Transcriptional Network of Diffuse Large B Cell Lymphoma of the Activated B Cell-Like Type

scientific article published on 15 July 2020

SAKK38/07 study: integration of baseline metabolic heterogeneity and metabolic tumor volume in DLBCL prognostic model

scientific article published on 01 March 2020

Single and combined BTK and PI3Kδ inhibition with acalabrutinib and ACP-319 in pre-clinical models of aggressive lymphomas

scientific article published on 29 July 2019

TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation ⬇️

scientific article published on 25 February 2015

The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs.

scientific article

The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents

scientific article published on 10 June 2019

The Novel TORC1/2 Kinase Inhibitor PQR620 Has Anti-Tumor Activity in Lymphomas as a Single Agent and in Combination with Venetoclax

scientific article published on 04 June 2019

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

scientific article (publication date: 4 January 2016)

The genetic landscape of dural marginal zone lymphomas

scientific article published on 27 May 2016

The genetics of nodal marginal zone lymphoma

scientific article published on 22 June 2016

The novel atypical retinoid ST5589 down-regulates Aurora Kinase A and has anti-tumour activity in lymphoma pre-clinical models.

scientific article published on 3 August 2015

Toll-like receptor 3 (TLR3) activation induces microRNA-dependent reexpression of functional RARβ and tumor regression

scientific article published on 28 May 2013

Trabectedin is a novel chemotherapy agent for diffuse large B cell lymphoma.

scientific article published on 2 April 2018

Trisomy 12 CLLs progress through NOTCH1 mutations ⬇️

scientific article published on August 20, 2012

Unraveling transformation of follicular lymphoma to diffuse large B-cell lymphoma

scientific article published on 25 February 2019

Whole exome sequencing reveals mutations in FAT1 tumor suppressor gene clinically impacting on peripheral T-cell lymphoma not otherwise specified

scientific article published on 25 April 2019

Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

scientific article published on 12 September 2016

cuRnet: an R package for graph traversing on GPU

scholarly article by Vincenzo Bonnici published in October 2018

miR-15b/16-2 deletion promotes B-cell malignancies

scientific article

miR-EdiTar: a database of predicted A-to-I edited miRNA target sites

scientific article

miR-Synth: a computational resource for the design of multi-site multi-target synthetic miRNAs

scientific article

microRNA classifiers are powerful diagnostic/prognostic tools in ALK-, EGFR-, and KRAS-driven lung cancers

scientific article

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