List of works - Ignazio Castagliuolo

1,6-Dimethyl-4-hydroxy-3-pyridinecarboxylic acid and 4-hydroxy-2-methyl-3-pyridinecarboxylic acid as new possible chelating agents for iron and aluminium

scientific article

A human antibody binds to alpha-galactose receptors and mimics the effects of Clostridium difficile toxin A in rat colon

scientific article published on 01 June 1996

Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC.

scientific article published on 04 February 2016

Adenosine-mediated enteric neuromuscular function is affected during herpes simplex virus type 1 infection of rat enteric nervous system

scientific article

Aggregating phenotype in Lactobacillus crispatus determines intestinal colonization and TLR2 and TLR4 modulation in murine colonic mucosa.

scientific article published on 18 July 2007

Altered ion channel activity in murine colonic smooth muscle myocytes in an experimental colitis model

scientific article published on 01 August 2000

Beneficial effect of auto-aggregating Lactobacillus crispatus on experimentally induced colitis in mice.

scientific article

Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage

scientific article published on 8 May 2015

CD80 down-regulation is associated to aberrant DNA methylation in non-inflammatory colon carcinogenesis

scientific article

Changes in microRNA expression during disease progression in patients with chronic viral hepatitis

scientific article published on 13 January 2015

Characterization of a new CDC73 missense mutation that impairs Parafibromin expression and nucleolar localization

scientific article

Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury

scientific journal article

Clostridium difficile TxAC314 and SLP-36kDa enhance the immune response toward a co-administered antigen

scientific article published on 01 June 2008

Clostridium difficile toxin A carboxyl-terminus peptide lacking ADP-ribosyltransferase activity acts as a mucosal adjuvant.

scientific article

Clostridium difficile-associated diarrhea and colitis: pathogenesis and therapy

scientific article published on 01 July 1993

Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation

scientific article published on October 2010

Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

scientific article published on 26 March 2015

Detection of sites of infection in mice using 99mTc-labeled PN(2)S-PEG conjugated to UBI and 99mTc-UBI: a comparative biodistribution study.

scientific article

Direct evidence of mast cell involvement in Clostridium difficile toxin A-induced enteritis in mice

scientific article published on 01 May 1998

Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors

scientific article

Disinfection of ocular cells and tissues by atmospheric-pressure cold plasma

scientific article

Driving h-osteoblast adhesion and proliferation on titania: peptide hydrogels decorated with growth factors and adhesive conjugates.

scientific article published in June 2014

Electrospun Scaffolds for Osteoblast Cells: Peptide-Induced Concentration-Dependent Improvements of Polycaprolactone

scientific article

Electrospun scaffolds of self-assembling peptides with poly(ethylene oxide) for bone tissue engineering

scientific article published on 21 February 2011

Engineered E. coli delivers therapeutic genes to the colonic mucosa.

scientific article published on July 2005

Epidermal growth factor receptor transactivation mediates substance P-induced mitogenic responses in U-373 MG cells

scientific article published on 01 August 2000

Essential oil of Lindera neesiana fruit: chemical analysis and its potential use in topical applications.

scientific article published on 6 July 2009

Gene therapy of thyroid cancer via retrovirally-driven combined expression of human interleukin-2 and herpes simplex virus thymidine kinase

scientific article published on January 2003

Helium generated cold plasma finely regulates activation of human fibroblast-like primary cells

scientific article

Improvement of Anselme's adhesion model for evaluating human osteoblast response to peptide-grafted titanium surfaces

scientific article published on 22 June 2007

Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats.

scientific article

Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts

scientific article

Inflammatory colonic carcinogenesis: a review on pathogenesis and immunosurveillance mechanisms in ulcerative colitis

scientific article

Innate Immune Environment in Ileal Pouch Mucosa: α5 Defensin Up-regulation as Predictor of Chronic/Relapsing Pouchitis

Intranasal delivery of DNA encoding antigens of Mycobacterium tuberculosis by non-pathogenic invasive Escherichia coli.

scientific article

Lactobacillus crispatus M247-derived H2O2 acts as a signal transducing molecule activating peroxisome proliferator activated receptor-gamma in the intestinal mucosa.

scientific article

MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells

scientific article published on 22 September 2011

Mechanisms underlying the attachment and spreading of human osteoblasts: from transient interactions to focal adhesions on vitronectin-grafted bioactive surfaces.

scientific article

MiR-155 modulates the inflammatory phenotype of intestinal myofibroblasts by targeting SOCS1 in ulcerative colitis

scientific article published on 22 May 2015

Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance

scientific article published on 19 October 2015

Modulation of retrovirally driven therapeutic genes by mutant TP53 in anaplastic thyroid carcinoma.

scientific article

Mucosal genetic immunization against four adhesins protects against Staphylococcus aureus-induced mastitis in mice.

scientific article published on 15 March 2006

Mucosal immune environment in colonic carcinogenesis: CD80 expression is associated to oxidative DNA damage and TLR4–NFκB signalling

Neuroimmune mechanisms of intestinal responses to stress. Role of corticotropin-releasing factor and neurotensin.

scientific article published in May 1998

Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum.

scientific article published in September 1994

Neuropeptide neurotensin stimulates intestinal wound healing following chronic intestinal inflammation

scientific article

Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin

scientific article published on 01 August 1996

Osteogenic properties of a short BMP-2 chimera peptide.

scientific article published in September 2015

Peroxisome proliferator-activated receptor-γ mediates the anti-inflammatory effect of 3-hydroxy-4-pyridinecarboxylic acid derivatives: synthesis and biological evaluation.

scientific article

Preliminary chemico-biological studies on Ru(III) compounds with S-methyl pyrrolidine/dimethyl dithiocarbamate.

scientific article

Quinazoline-based multi-tyrosine kinase inhibitors: synthesis, modeling, antitumor and antiangiogenic properties.

scientific article published on 6 July 2013

Rectal administration of Lactobacillus casei DG modifies flora composition and Toll-like receptor expression in colonic mucosa of patients with mild ulcerative colitis.

scientific article

Relationship between mucosa-associated microbiota and inflammatory parameters in the ileal pouch after restorative proctocolectomy for ulcerative colitis

scientific article published on 05 May 2011

Relationship between pouch microbiota and pouchitis following restorative proctocolectomy for ulcerative colitis.

scientific article

Relationship between virulence factor genes in bovine Staphylococcus aureus subclinical mastitis isolates and binding to anti-adhesin antibodies

article

Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury.

scientific article

Role of the A(2B) receptor-adenosine deaminase complex in colonic dysmotility associated with bowel inflammation in rats.

scientific article published on March 2014

Ru(III)-based compounds with sulfur donor ligands: synthesis, characterization, electrochemical behaviour and anticancer activity.

scientific article

Self-assembling peptide-enriched electrospun polycaprolactone scaffolds promote the h-osteoblast adhesion and modulate differentiation-associated gene expression

scientific article published on 20 August 2012

Snail1 transcription factor is a critical mediator of hepatic stellate cell activation following hepatic injury.

scientific article published on 18 November 2010

Staphylococcus aureus Efb protein expression in Nicotiana tabacum and immune response to oral administration

scientific article published on 16 November 2012

Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents

scientific article published on 18 March 2013

Synthesis and in vitro and in vivo antitumor activity of 2-phenylpyrroloquinolin-4-ones

scientific article

Synthesis and in vitro evaluation of 3h-pyrrolo[3,2-f]-quinolin-9-one derivatives that show potent and selective anti-leukemic activity

scientific article

Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity.

scientific article published on 16 October 2013

Synthesis of triazenoazaindoles: a new class of triazenes with antitumor activity.

scientific article published on 26 April 2011

Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles

scientific article

Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma

scientific article

TLR2 and TLR4 up-regulation and colonization of the ileal mucosa by Clostridiaceae spp. in chronic/relapsing pouchitis.

scientific article published on 5 May 2011

The Importance of Descriptor-Based Clusterization in QSAR Models Development: Tyrosine Kinases Inhibitors as a Key Study.

scientific article published on 2 August 2011

Toll like receptor-2 regulates production of glial-derived neurotrophic factors in murine intestinal smooth muscle cells

scientific article

Transcriptionally targeted retroviral vector for combined suicide and immunomodulating gene therapy of thyroid cancer

scientific article published in November 2002

Triterpene glycosides with in vitro anti-inflammatory activity from Cyclamen repandum tubers

scientific article

UVB photolysis of hydrocortisone 21-acetate.

scientific article

Using the TOPS-MODE approach to fit multi-target QSAR models for tyrosine kinases inhibitors

scientific article published on 11 March 2011

List of works by Ignazio Castagliuolo

1,6-Dimethyl-4-hydroxy-3-pyridinecarboxylic acid and 4-hydroxy-2-methyl-3-pyridinecarboxylic acid as new possible chelating agents for iron and aluminium

A human antibody binds to alpha-galactose receptors and mimics the effects of Clostridium difficile toxin A in rat colon

Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC.

Adenosine-mediated enteric neuromuscular function is affected during herpes simplex virus type 1 infection of rat enteric nervous system

Aggregating phenotype in Lactobacillus crispatus determines intestinal colonization and TLR2 and TLR4 modulation in murine colonic mucosa.

Altered ion channel activity in murine colonic smooth muscle myocytes in an experimental colitis model

Beneficial effect of auto-aggregating Lactobacillus crispatus on experimentally induced colitis in mice.

Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage

CD80 down-regulation is associated to aberrant DNA methylation in non-inflammatory colon carcinogenesis

Changes in microRNA expression during disease progression in patients with chronic viral hepatitis

Characterization of a new CDC73 missense mutation that impairs Parafibromin expression and nucleolar localization

Cingulin is dispensable for epithelial barrier function and tight junction structure, and plays a role in the control of claudin-2 expression and response to duodenal mucosa injury

Clostridium difficile TxAC314 and SLP-36kDa enhance the immune response toward a co-administered antigen

Clostridium difficile toxin A carboxyl-terminus peptide lacking ADP-ribosyltransferase activity acts as a mucosal adjuvant.

Clostridium difficile-associated diarrhea and colitis: pathogenesis and therapy

Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation

Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

Detection of sites of infection in mice using 99mTc-labeled PN(2)S-PEG conjugated to UBI and 99mTc-UBI: a comparative biodistribution study.

Direct evidence of mast cell involvement in Clostridium difficile toxin A-induced enteritis in mice

Discovery of biarylaminoquinazolines as novel tubulin polymerization inhibitors

Disinfection of ocular cells and tissues by atmospheric-pressure cold plasma

Driving h-osteoblast adhesion and proliferation on titania: peptide hydrogels decorated with growth factors and adhesive conjugates.

Electrospun Scaffolds for Osteoblast Cells: Peptide-Induced Concentration-Dependent Improvements of Polycaprolactone

Electrospun scaffolds of self-assembling peptides with poly(ethylene oxide) for bone tissue engineering

Engineered E. coli delivers therapeutic genes to the colonic mucosa.

Epidermal growth factor receptor transactivation mediates substance P-induced mitogenic responses in U-373 MG cells

Essential oil of Lindera neesiana fruit: chemical analysis and its potential use in topical applications.

Gene therapy of thyroid cancer via retrovirally-driven combined expression of human interleukin-2 and herpes simplex virus thymidine kinase

Helium generated cold plasma finely regulates activation of human fibroblast-like primary cells

Improvement of Anselme's adhesion model for evaluating human osteoblast response to peptide-grafted titanium surfaces

Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats.

Induction of erythroid differentiation and increased globin mRNA production with furocoumarins and their photoproducts

Inflammatory colonic carcinogenesis: a review on pathogenesis and immunosurveillance mechanisms in ulcerative colitis

Innate Immune Environment in Ileal Pouch Mucosa: α5 Defensin Up-regulation as Predictor of Chronic/Relapsing Pouchitis

Intranasal delivery of DNA encoding antigens of Mycobacterium tuberculosis by non-pathogenic invasive Escherichia coli.

Lactobacillus crispatus M247-derived H2O2 acts as a signal transducing molecule activating peroxisome proliferator activated receptor-gamma in the intestinal mucosa.

MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells

Mechanisms underlying the attachment and spreading of human osteoblasts: from transient interactions to focal adhesions on vitronectin-grafted bioactive surfaces.

MiR-155 modulates the inflammatory phenotype of intestinal myofibroblasts by targeting SOCS1 in ulcerative colitis

Mismatch repair gene defects in sporadic colorectal cancer enhance immune surveillance

Modulation of retrovirally driven therapeutic genes by mutant TP53 in anaplastic thyroid carcinoma.

Mucosal genetic immunization against four adhesins protects against Staphylococcus aureus-induced mastitis in mice.

Mucosal immune environment in colonic carcinogenesis: CD80 expression is associated to oxidative DNA damage and TLR4–NFκB signalling

Neuroimmune mechanisms of intestinal responses to stress. Role of corticotropin-releasing factor and neurotensin.

Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio cholerae enterotoxin in rat ileum.

Neuropeptide neurotensin stimulates intestinal wound healing following chronic intestinal inflammation

Nitric oxide inhibits rat intestinal secretion by Clostridium difficile toxin A but not Vibrio cholerae enterotoxin

Osteogenic properties of a short BMP-2 chimera peptide.

Peroxisome proliferator-activated receptor-γ mediates the anti-inflammatory effect of 3-hydroxy-4-pyridinecarboxylic acid derivatives: synthesis and biological evaluation.

Preliminary chemico-biological studies on Ru(III) compounds with S-methyl pyrrolidine/dimethyl dithiocarbamate.

Quinazoline-based multi-tyrosine kinase inhibitors: synthesis, modeling, antitumor and antiangiogenic properties.

Rectal administration of Lactobacillus casei DG modifies flora composition and Toll-like receptor expression in colonic mucosa of patients with mild ulcerative colitis.

Relationship between mucosa-associated microbiota and inflammatory parameters in the ileal pouch after restorative proctocolectomy for ulcerative colitis

Relationship between pouch microbiota and pouchitis following restorative proctocolectomy for ulcerative colitis.

Relationship between virulence factor genes in bovine Staphylococcus aureus subclinical mastitis isolates and binding to anti-adhesin antibodies

Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury.

Role of the A(2B) receptor-adenosine deaminase complex in colonic dysmotility associated with bowel inflammation in rats.

Ru(III)-based compounds with sulfur donor ligands: synthesis, characterization, electrochemical behaviour and anticancer activity.

Self-assembling peptide-enriched electrospun polycaprolactone scaffolds promote the h-osteoblast adhesion and modulate differentiation-associated gene expression

Snail1 transcription factor is a critical mediator of hepatic stellate cell activation following hepatic injury.

Staphylococcus aureus Efb protein expression in Nicotiana tabacum and immune response to oral administration

Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents

Synthesis and in vitro and in vivo antitumor activity of 2-phenylpyrroloquinolin-4-ones

Synthesis and in vitro evaluation of 3h-pyrrolo[3,2-f]-quinolin-9-one derivatives that show potent and selective anti-leukemic activity

Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity.

Synthesis of triazenoazaindoles: a new class of triazenes with antitumor activity.

Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles

Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma

TLR2 and TLR4 up-regulation and colonization of the ileal mucosa by Clostridiaceae spp. in chronic/relapsing pouchitis.

The Importance of Descriptor-Based Clusterization in QSAR Models Development: Tyrosine Kinases Inhibitors as a Key Study.

Toll like receptor-2 regulates production of glial-derived neurotrophic factors in murine intestinal smooth muscle cells

Transcriptionally targeted retroviral vector for combined suicide and immunomodulating gene therapy of thyroid cancer

Triterpene glycosides with in vitro anti-inflammatory activity from Cyclamen repandum tubers

UVB photolysis of hydrocortisone 21-acetate.

Using the TOPS-MODE approach to fit multi-target QSAR models for tyrosine kinases inhibitors