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List of works by Paolo Vigneri

A population-based study of chronic myeloid leukemia patients treated with imatinib in first line

scientific article

Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment

scientific article published on 02 July 2019

Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery

scientific article published on 18 August 2021

Altered expression of c-IAP1, survivin, and Smac contributes to chemotherapy resistance in thyroid cancer cells.

scientific article published on April 2006

An optimized workflow to evaluate estrogen receptor gene mutations in small amounts of cell-free DNA

article

BCR-ABL nuclear entrapment kills human CML cells: ex vivo study on 35 patients with the combination of imatinib mesylate and leptomycin B.

scientific article published on 25 October 2005

BCR-ABL residues interacting with ponatinib are critical to preserve the tumorigenic potential of the oncoprotein

scientific article published on 02 December 2013

BRIT1/MCPH1 expression in chronic myeloid leukemia and its regulation of the G2/M checkpoint.

scientific article published on 16 September 2011

Biological effects of insulin and its analogs on cancer cells with different insulin family receptor expression

scientific article published on November 2014

Biomarkers and prognostic factors for malignant pleural mesothelioma

scientific article

Cancer Stem Cells and Chemosensitivity ⬇️

scientific article published on May 27, 2011

Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib

scientific article

Chk1 Inhibition Restores Inotuzumab Ozogamicin Citotoxicity in CD22-Positive Cells Expressing Mutant p53

scientific article published on 18 February 2019

Clinical Implications of Discordant Early Molecular Responses in CML Patients Treated with Imatinib. ⬇️

scientific article published on 6 May 2019

Clinical relevance of the association of interferon alfa to imatinib in chronic myeloid leukemia therapy ⬇️

scientific article published on May 26, 2012

Concomitant and feasible treatment with dasatinib and the anti-EGFR antibody cetuximab plus radiotherapy in a CML patient with multiple squamous neoplasias.

scientific article published in January 2010

Current management of CML patients: Summary of the Italian Consensus Meeting held in Rome, April 11-12, 2013.

scientific article published on 17 December 2013

DDR1 regulates thyroid cancer cell differentiation via IGF-2/IR-A autocrine signaling loop

scientific article published on 01 January 2019

Dasatinib is safe and effective in unselected chronic myeloid leukaemia elderly patients resistant/intolerant to imatinib

scientific article published on 25 June 2011

Detection of an activating mutation of the thyrotropin receptor in a case of an autonomously hyperfunctioning thyroid insular carcinoma

scientific article published on 01 March 1997

Diagnosis of blastic phase of chronic myeloid leukemia

scientific article published on 21 March 2012

Discoidin domain receptor 1 modulates insulin receptor signaling and biological responses in breast cancer cells

scientific article published on 19 May 2017

False positive 131I total body scan due to bilateral polycystic renal disease ⬇️

scientific article published on 01 June 1997

Flow Cytometric Immunobead Assay for Detection of BCR-ABL1 Fusion Proteins in Chronic Myleoid Leukemia: Comparison with FISH and PCR Techniques

scientific article published on 25 June 2015

Frontline Dasatinib Treatment in a "Real-Life" Cohort of Patients Older than 65 Years with Chronic Myeloid Leukemia

scientific article published on September 2016

Ground glass opacities management in the lung cancer screening era.

scientific article

Hammersmith score application identifies chronic myeloid leukemia patients with poor prognosis before treatment with second-generation tyrosine kinase inhibitors

scientific article published on 01 June 2011

High BCR-ABL/GUSIS Levels at Diagnosis of Chronic Phase CML Are Associated with Unfavorable Responses to Standard-Dose Imatinib

scientific article published on 19 September 2017

Hyperdiploidy associated with a high BCR-ABL transcript level may identify patients at risk of progression in chronic myeloid leukemia

scientific article published on 05 October 2011

IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation.

scientific article published on 20 January 2014

IRF5 promotes the proliferation of human thyroid cancer cells.

scientific article

Imatinib and polypharmacy in very old patients with chronic myeloid leukemia: effects on response rate, toxicity and outcome

scientific article published on 27 August 2016

Imatinib discontinuation: realistic for patients with chronic myeloid leukaemia achieving complete molecular remission? ⬇️

scientific article published on 01 February 2011

Imatinib mesylate in chronic myeloid leukemia: frontline treatment and long-term outcomes.

scientific article published on 6 February 2016

Impact of BCR-ABL mutations on response to dasatinib after imatinib failure in elderly patients with chronic-phase chronic myeloid leukemia

scientific article published on 10 October 2012

Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.

scientific article

Infliximab therapy in hematologic malignancies: handle with care.

scientific article published in August 2012

Insular Carcinoma

scientific article published on 01 December 1997

Insulin Receptor Isoforms in Cancer ⬇️

scientific article published on 16 November 2018

Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL.

scientific article

Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release

scientific article

Long-Term Molecular Remission Achieved by Antibody Anti-CD22 and Ponatinib in a Patient Affected by Ph'+ Acute Lymphoblastic Leukemia Relapsed after Second Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report

scientific article published on 29 October 2018

Mechanistic Translation of Melanoma Genetic Landscape in Enriched Pathways and Oncogenic Protein-Protein Interactions

scientific article published on 01 May 2022

Mesenchymal Stem Cells (MSC) Regulate Activation of Granulocyte-Like Myeloid Derived Suppressor Cells (G-MDSC) in Chronic Myeloid Leukemia Patients

scientific article

Modelling of the ABL and ARG proteins predicts two functionally critical regions that are natively unfolded

scientific article

Molecular Alterations in Thyroid Cancer: From Bench to Clinical Practice

scientific article published on 13 September 2019

Myeloid derived suppressor cells (MDSCs) are increased and exert immunosuppressive activity together with polymorphonuclear leukocytes (PMNs) in chronic myeloid leukemia patients.

scientific article

New Insights in Thyroid Cancer and p53 Family Proteins.

scientific article

Non ABL-directed inhibitors as alternative treatment strategies for chronic myeloid leukemia

scientific article

Nuclear entrapment of BCR-ABL by combining imatinib mesylate with leptomycin B does not eliminate CD34+ chronic myeloid leukaemia cells.

scientific article published on 8 January 2009

Personalized strategies for CML patients considering discontinuation of tyrosine kinase inhibitors treatment.

scientific article

Predictive and Prognostic Value of Early Disease Progression by PET Evaluation in Advanced Non-Small Cell Lung Cancer.

scientific article published on 11 November 2016

Roles of Interferon Regulatory Factors in Chronic Myeloid Leukemia

scientific article published on 04 January 2016

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

scientific article published on 13 April 2009

Targeting autophagy potentiates tyrosine kinaseinhibitor–induced cell death in Philadelphia chromosome–positivecells, including primary CML stem cells.

scientific article

The BCR-ABL1 transcript type influences response and outcome in Philadelphia chromosome-positive chronic myeloid leukemia patients treated frontline with imatinib

scientific article published on 2 May 2017

The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy

scientific article

The PU.1 transcription factor induces cyclin D2 expression in U937 cells

scientific article published on 19 October 2006

Towards a need to a “biological Sokal risk” in the era of tyrosine kinase inhibitors in choosing front-line therapy in chronic myeloid leukemia ⬇️

scientific article published on April 12, 2012

Unsuccessful dasatinib therapy in a refractory patient with chronic lymphocytic leukemia.

scientific article published on 3 August 2010

Utility of flow cytometry as a screening tool for transplant donors for chronic lymphocytic leukemia

scientific article published on 07 May 2010

V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells.

scientific article published on 12 February 2010

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