List of works - Lewis L Hsu

"Maximum tolerated dose" vs "fixed low-dose" hydroxyurea for treatment of adults with sickle cell anemia

scientific article published on 06 February 2019

A dose-ranging study of ticagrelor in children aged 3-17 years with sickle cell disease: A 2-part phase 2 study

scientific article published on 02 October 2018

Adverse Reactions to Pneumococcal Vaccine in Pediatric and Adolescent Patients with Sickle Cell Disease.

scientific article

Alpha Thalassemia is associated with decreased risk of abnormal transcranial Doppler ultrasonography in children with sickle cell anemia.

scientific article published in August 2003

An Electronic Teaching Module for Improving Knowledge of Self-Management of Vaso-Occlusive Pain Crises in Patients With Sickle Cell Disease: Pilot Questionnaire Study

scientific article published on 20 June 2019

An educational symposium for patients with sickle cell disease and their families: results from surveys of knowledge and factors influencing decisions about hematopoietic stem cell transplant

scientific article published on 30 July 2013

An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease

scientific article published on March 2014

Assessing the appropriateness of medical care

scientific article published on 01 November 1998

Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease.

scientific article published on 21 August 2003

Clinical Manifestations of Sickle Cell Anemia: Infants and Children

Clinical trial implementation and recruitment: Lessons learned from the early closure of a randomized clinical trial ⬇️

scientific article published on December 2, 2011

Community Health Workers as Support for Sickle Cell Care

scientific article published on July 2016

Comparing abstract numerical and visual depictions of risk in survey of parental assessment of risk in sickle cell hydroxyurea treatment.

scientific article published in January 2011

Comparison of mechanisms of anemia in mice with sickle cell disease and beta-thalassemia: peripheral destruction, ineffective erythropoiesis, and phospholipid scramblase-mediated phosphatidylserine exposure

scientific article published in May 2002

Comparison of patients from Nigeria and the USA highlights modifiable risk factors for sickle cell anemia complications

scientific article

Disrupted erythropoietin signalling promotes obesity and alters hypothalamus proopiomelanocortin production.

scientific article published on November 2011

Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia

scientific article published on 01 February 2007

Erythrocytes are the major intravascular storage sites of nitrite in human blood.

scientific article published on 17 March 2005

Establishment of a transgenic sickle-cell mouse model to study the pathophysiology of priapism

scientific article

Ethyl pyruvate decreased early nuclear factor-kappaB levels but worsened survival in lipopolysaccharide-challenged mice.

scientific article published in April 2008

Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: a retrospective cohort study of 137 children with sickle cell anemia

scientific article published on 01 November 2006

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability

scientific article published on April 2007

Hepatomegaly in neuroblastoma stage 4s: criteria for treatment of the vulnerable neonate

scientific article published on 01 December 1996

Hydroxyurea makes inflammation "just right"?

scientific article published on 01 February 2012

IMPROVE trial: a randomized controlled trial of patient-controlled analgesia for sickle cell painful episodes: rationale, design challenges, initial experience, and recommendations for future studies

scientific article published on April 2013

Impact of PCA strategies on pain intensity and functional assessment measures in adults with sickle cell disease during hospitalized vaso-occlusive episodes.

scientific article

Magnetic resonance angiography in children with sickle cell disease and abnormal transcranial Doppler ultrasonography findings enrolled in the STOP study

scientific article

Murine and math models for the level of stable mixed chimerism to cure beta-thalassemia by nonmyeloablative bone marrow transplantation.

scientific article

Neurocognitive functioning and magnetic resonance imaging in children with sickle cell disease.

scientific article published on October 2000

Neurodevelopmental deficits among infants and toddlers with sickle cell disease.

scientific article published in July 2013

Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial

scientific article

Normal saline bolus use in pediatric emergency departments is associated with poorer pain control in children with sickle cell anemia and vaso-occlusive pain.

scientific article published on 29 April 2019

Opioid patient controlled analgesia use during the initial experience with the IMPROVE PCA trial: A phase III analgesic trial for hospitalized sickle cell patients with painful episodes ⬇️

scientific article published on September 22, 2011

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.

scientific article published on 7 September 2017

Oxygen regulates tissue nitrite metabolism

scientific article

Parthenolide has limited effects on nuclear factor-kappa beta increases and worsens survival in lipopolysaccharide-challenged C57BL/6J mice.

scientific article published on March 2006

Pathology of "Berkeley" sickle-cell mice includes gallstones and priapism

scientific article published on 01 April 2006

Peripheral Arterial Tonometry in Assessing Endothelial Dysfunction in Pediatric Sickle Cell Disease

Peripheral arterial tonometry in assessing endothelial dysfunction in pediatric sickle cell disease

scientific article published in November 2009

Physician-diagnosed asthma and acute chest syndrome: associations with NOS polymorphisms.

scientific article published on April 2007

Platelets decline during Vaso-occlusive crisis as a predictor of acute chest syndrome in sickle cell disease

scientific article published on 9 October 2015

Poor school and cognitive functioning with silent cerebral infarcts and sickle cell disease.

scientific article published in April 2001

Post-Translational Inactivation of Endothelial Nitric Oxide Synthase in the Transgenic Sickle Cell Mouse Penis ⬇️

scientific article published on December 8, 2010

Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography

scientific article published in July 1998

Prevention of stroke by transfusions in children with sickle cell anemia

scientific article published on 01 November 1998

Program expansion of a day hospital dedicated to manage sickle cell pain.

scientific article published on 11 October 2017

Pulmonary hypertension of sickle cell disease beyond classification constraints

scientific article published on 30 April 2014

RBC Adhesion to Cremaster Endothelum in Mice with Abnormal Hemoglobin is Increased by Topical Endotoxin ⬇️

scientific article published on June 30, 1998

Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use.

scientific article published on 2 March 2015

Refining the value of secretory phospholipase A2 as a predictor of acute chest syndrome in sickle cell disease: results of a feasibility study (PROACTIVE)

scientific article

Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke

scientific article published on March 2002

Risk-resistance adaptation model for caregivers and their children with sickle cell syndromes

scientific article published in January 2000

SB203580, a p38 inhibitor, improved cardiac function but worsened lung injury and survival during Escherichia coli pneumonia in mice.

scientific article

Self-Reported Physical Activity and Exercise Patterns in Children With Sickle Cell Disease

scientific article published on 22 May 2017

Sickle Cell Disease-Genetics, Pathophysiology, Clinical Presentation and Treatment

scientific article published on 07 May 2019

Sickle erythrocyte adherence to endothelium at low shear: role of shear stress in propagation of vaso-occlusion.

scientific article published in July 2002

Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress

scientific article

Social information processing and magnetic resonance imaging in children with sickle cell disease.

scientific article published on July 2001

Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia ⬇️

scientific article published on January 1, 2001

Stroke prevention trial in sickle cell anemia.

scientific article published on February 1998

Subacute Hemolysis in Sickle Cell Mice Causes Priapism Secondary to NO Imbalance and PDE5 Dysregulation

scientific article

The sickle cell disease implementation consortium: Translating evidence-based guidelines into practice for sickle cell disease.

scientific article published on 17 October 2018

Timely Care for Sickle Cell

scientific article published on 13 January 2017

Transgenic HbS mouse neutrophils in increased susceptibility to acute lung injury: implications for sickle acute chest syndrome

scientific article published on 01 July 1999

List of works by Lewis L Hsu

"Maximum tolerated dose" vs "fixed low-dose" hydroxyurea for treatment of adults with sickle cell anemia

A dose-ranging study of ticagrelor in children aged 3-17 years with sickle cell disease: A 2-part phase 2 study

Adverse Reactions to Pneumococcal Vaccine in Pediatric and Adolescent Patients with Sickle Cell Disease.

Alpha Thalassemia is associated with decreased risk of abnormal transcranial Doppler ultrasonography in children with sickle cell anemia.

An Electronic Teaching Module for Improving Knowledge of Self-Management of Vaso-Occlusive Pain Crises in Patients With Sickle Cell Disease: Pilot Questionnaire Study

An educational symposium for patients with sickle cell disease and their families: results from surveys of knowledge and factors influencing decisions about hematopoietic stem cell transplant

An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease

Assessing the appropriateness of medical care

Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease.

Clinical Manifestations of Sickle Cell Anemia: Infants and Children

Clinical trial implementation and recruitment: Lessons learned from the early closure of a randomized clinical trial ⬇️

Community Health Workers as Support for Sickle Cell Care

Comparing abstract numerical and visual depictions of risk in survey of parental assessment of risk in sickle cell hydroxyurea treatment.

Comparison of mechanisms of anemia in mice with sickle cell disease and beta-thalassemia: peripheral destruction, ineffective erythropoiesis, and phospholipid scramblase-mediated phosphatidylserine exposure

Comparison of patients from Nigeria and the USA highlights modifiable risk factors for sickle cell anemia complications

Disrupted erythropoietin signalling promotes obesity and alters hypothalamus proopiomelanocortin production.

Effect of myeloablative bone marrow transplantation on growth in children with sickle cell anaemia: results of the multicenter study of haematopoietic cell transplantation for sickle cell anaemia

Erythrocytes are the major intravascular storage sites of nitrite in human blood.

Establishment of a transgenic sickle-cell mouse model to study the pathophysiology of priapism

Ethyl pyruvate decreased early nuclear factor-kappaB levels but worsened survival in lipopolysaccharide-challenged mice.

Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: a retrospective cohort study of 137 children with sickle cell anemia

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability

Hepatomegaly in neuroblastoma stage 4s: criteria for treatment of the vulnerable neonate

Hydroxyurea makes inflammation "just right"?

IMPROVE trial: a randomized controlled trial of patient-controlled analgesia for sickle cell painful episodes: rationale, design challenges, initial experience, and recommendations for future studies

Impact of PCA strategies on pain intensity and functional assessment measures in adults with sickle cell disease during hospitalized vaso-occlusive episodes.

Magnetic resonance angiography in children with sickle cell disease and abnormal transcranial Doppler ultrasonography findings enrolled in the STOP study

Murine and math models for the level of stable mixed chimerism to cure beta-thalassemia by nonmyeloablative bone marrow transplantation.

Neurocognitive functioning and magnetic resonance imaging in children with sickle cell disease.

Neurodevelopmental deficits among infants and toddlers with sickle cell disease.

Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial

Normal saline bolus use in pediatric emergency departments is associated with poorer pain control in children with sickle cell anemia and vaso-occlusive pain.

Opioid patient controlled analgesia use during the initial experience with the IMPROVE PCA trial: A phase III analgesic trial for hospitalized sickle cell patients with painful episodes ⬇️

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.

Oxygen regulates tissue nitrite metabolism

Parthenolide has limited effects on nuclear factor-kappa beta increases and worsens survival in lipopolysaccharide-challenged C57BL/6J mice.

Pathology of "Berkeley" sickle-cell mice includes gallstones and priapism

Peripheral Arterial Tonometry in Assessing Endothelial Dysfunction in Pediatric Sickle Cell Disease

Peripheral arterial tonometry in assessing endothelial dysfunction in pediatric sickle cell disease

Physician-diagnosed asthma and acute chest syndrome: associations with NOS polymorphisms.

Platelets decline during Vaso-occlusive crisis as a predictor of acute chest syndrome in sickle cell disease

Poor school and cognitive functioning with silent cerebral infarcts and sickle cell disease.

Post-Translational Inactivation of Endothelial Nitric Oxide Synthase in the Transgenic Sickle Cell Mouse Penis ⬇️

Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography

Prevention of stroke by transfusions in children with sickle cell anemia

Program expansion of a day hospital dedicated to manage sickle cell pain.

Pulmonary hypertension of sickle cell disease beyond classification constraints

RBC Adhesion to Cremaster Endothelum in Mice with Abnormal Hemoglobin is Increased by Topical Endotoxin ⬇️

Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use.

Refining the value of secretory phospholipase A2 as a predictor of acute chest syndrome in sickle cell disease: results of a feasibility study (PROACTIVE)

Risk of recurrent stroke in children with sickle cell disease receiving blood transfusion therapy for at least five years after initial stroke

Risk-resistance adaptation model for caregivers and their children with sickle cell syndromes

SB203580, a p38 inhibitor, improved cardiac function but worsened lung injury and survival during Escherichia coli pneumonia in mice.

Self-Reported Physical Activity and Exercise Patterns in Children With Sickle Cell Disease

Sickle Cell Disease-Genetics, Pathophysiology, Clinical Presentation and Treatment

Sickle erythrocyte adherence to endothelium at low shear: role of shear stress in propagation of vaso-occlusion.

Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress

Social information processing and magnetic resonance imaging in children with sickle cell disease.

Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia ⬇️

Stroke prevention trial in sickle cell anemia.

Subacute Hemolysis in Sickle Cell Mice Causes Priapism Secondary to NO Imbalance and PDE5 Dysregulation

The sickle cell disease implementation consortium: Translating evidence-based guidelines into practice for sickle cell disease.

Timely Care for Sickle Cell

Transgenic HbS mouse neutrophils in increased susceptibility to acute lung injury: implications for sickle acute chest syndrome

Treatment of intermediate-grade and high-grade non-Hodgkin's lymphoma