List of works - Éva Frank

A click approach to novel D-ring-substituted 16α-triazolylestrone derivatives and characterization of their antiproliferative properties

scientific article

A facile 'click' approach to novel 15β-triazolyl-5α-androstane derivatives, and an evaluation of their antiproliferative activities in vitro.

scientific article published on 12 January 2012

A facile access to novel steroidal 17-2'-(1',3',4')-oxadiazoles, and an evaluation of their cytotoxic activities in vitro.

scientific article published on 31 January 2014

An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17α-hydroxylase/C₁₇,₂₀-lyase.

scientific article published on 22 October 2013

Anti-Cancer Activity of Novel Dihydrotestosterone-Derived Ring A-Condensed Pyrazoles on Androgen Non-Responsive Prostate Cancer Cell Lines ⬇️

scientific article published on 02 May 2019

Anticancer and multidrug resistance-reversal effects of solanidine analogs synthetized from pregnadienolone acetate

scientific article published on 17 February 2014

Antiproliferative effects of some novel synthetic solanidine analogs on HL-60 human leukemia cells in vitro.

scientific article

Efficient access to novel androsteno-17-(1',3',4')-oxadiazoles and 17β-(1',3',4')-thiadiazoles via N-substituted hydrazone and N,N'-disubstituted hydrazine intermediates, and their pharmacological evaluation in vitro.

scientific article published on 7 May 2015

Efficient approach to androstene-fused arylpyrazolines as potent antiproliferative agents. Experimental and theoretical studies of substituent effects on BF(3)-catalyzed intramolecular [3 + 2] cycloadditions of olefinic phenylhydrazones.

scientific article published in March 2009

Efficient approach to novel 1α-triazolyl-5α-androstane derivatives as potent antiproliferative agents

scientific article published on 6 October 2011

Investigation of pH and substituent effects on the distribution ratio of novel steroidal ring D- and A-fused arylpyrazole regioisomers and evaluation of their cell-growth inhibitory effects in vitro.

scientific article published on 9 August 2017

Lewis acid-induced intramolecular access to novel steroidal ring D-condensed arylpyrazolines exerting in vitro cell-growth-inhibitory effects.

scientific article

Microwave-assisted stereoselective approach to novel steroidal ring D-fused 2-pyrazolines and an evaluation of their cell-growth inhibitory effects in vitro

scientific article published on 3 May 2016

Microwave-assisted synthesis of biologically relevant steroidal 17--pyrazol-5'-ones from a norpregnene precursor by a side-chain elongation/heterocyclization sequence

scientific article published on 08 October 2018

Multicomponent access to androstano-arylpyrimidines under microwave conditions and evaluation of their anti-cancer activity in vitro.

scientific article

Multistep Synthesis and In Vitro Anticancer Evaluation of 2-Pyrazolyl-Estradiol Derivatives, Pyrazolocoumarin-Estradiol Hybrids and Analogous Compounds

scientific article published on 04 September 2020

New steroid-fused P-heterocycles. Part I. Synthesis and conformational study of dioxaphosphorino[16,17-d]estrone derivatives

scientific article published on 15 February 2007

New steroid-fused P-heterocycles. Part II. Synthesis and conformational study of oxazaphosphorino[16,17-e]estrone derivatives

scientific article published on 13 February 2007

Regio- and stereoselective access to novel ring-condensed steroidal isoxazolines

scientific article published on 10 June 2014

Synthesis and in vitro antiproliferative activity of novel androst-5-ene triazolyl and tetrazolyl derivatives.

scientific article published on 9 June 2011

Synthesis and investigation of the anticancer effects of estrone-16-oxime ethers in vitro.

scientific article

Synthesis of novel 17-(4'-formyl)pyrazolylandrosta-5,16-dienes and their derivatives as potent 17α-hydroxylase/C17,20-lyase inhibitors or antiproliferative agents depending on the substitution pattern of the heteroring.

scientific article

Synthesis of sex hormone-derived modified steroids possessing antiproliferative activity ⬇️

scientific article published on March 14, 2013

Synthesis, characterization and biological evaluation of some novel 17-isoxazoles in the estrone series.

scientific article published on 18 May 2012

List of works by Éva Frank

A click approach to novel D-ring-substituted 16α-triazolylestrone derivatives and characterization of their antiproliferative properties

A facile 'click' approach to novel 15β-triazolyl-5α-androstane derivatives, and an evaluation of their antiproliferative activities in vitro.

A facile access to novel steroidal 17-2'-(1',3',4')-oxadiazoles, and an evaluation of their cytotoxic activities in vitro.

An efficient approach to novel 17-5'-(1',2',4')-oxadiazolyl androstenes via the cyclodehydration of cytotoxic O-steroidacylamidoximes, and an evaluation of their inhibitory action on 17α-hydroxylase/C₁₇,₂₀-lyase.

Anti-Cancer Activity of Novel Dihydrotestosterone-Derived Ring A-Condensed Pyrazoles on Androgen Non-Responsive Prostate Cancer Cell Lines ⬇️

Anticancer and multidrug resistance-reversal effects of solanidine analogs synthetized from pregnadienolone acetate

Antiproliferative effects of some novel synthetic solanidine analogs on HL-60 human leukemia cells in vitro.

Efficient access to novel androsteno-17-(1',3',4')-oxadiazoles and 17β-(1',3',4')-thiadiazoles via N-substituted hydrazone and N,N'-disubstituted hydrazine intermediates, and their pharmacological evaluation in vitro.

Efficient approach to androstene-fused arylpyrazolines as potent antiproliferative agents. Experimental and theoretical studies of substituent effects on BF(3)-catalyzed intramolecular [3 + 2] cycloadditions of olefinic phenylhydrazones.

Efficient approach to novel 1α-triazolyl-5α-androstane derivatives as potent antiproliferative agents

Investigation of pH and substituent effects on the distribution ratio of novel steroidal ring D- and A-fused arylpyrazole regioisomers and evaluation of their cell-growth inhibitory effects in vitro.

Lewis acid-induced intramolecular access to novel steroidal ring D-condensed arylpyrazolines exerting in vitro cell-growth-inhibitory effects.

Microwave-assisted stereoselective approach to novel steroidal ring D-fused 2-pyrazolines and an evaluation of their cell-growth inhibitory effects in vitro

Microwave-assisted synthesis of biologically relevant steroidal 17--pyrazol-5'-ones from a norpregnene precursor by a side-chain elongation/heterocyclization sequence

Multicomponent access to androstano-arylpyrimidines under microwave conditions and evaluation of their anti-cancer activity in vitro.

Multistep Synthesis and In Vitro Anticancer Evaluation of 2-Pyrazolyl-Estradiol Derivatives, Pyrazolocoumarin-Estradiol Hybrids and Analogous Compounds

New steroid-fused P-heterocycles. Part I. Synthesis and conformational study of dioxaphosphorino[16,17-d]estrone derivatives

New steroid-fused P-heterocycles. Part II. Synthesis and conformational study of oxazaphosphorino[16,17-e]estrone derivatives

Regio- and stereoselective access to novel ring-condensed steroidal isoxazolines

Synthesis and in vitro antiproliferative activity of novel androst-5-ene triazolyl and tetrazolyl derivatives.

Synthesis and investigation of the anticancer effects of estrone-16-oxime ethers in vitro.

Synthesis of novel 17-(4'-formyl)pyrazolylandrosta-5,16-dienes and their derivatives as potent 17α-hydroxylase/C17,20-lyase inhibitors or antiproliferative agents depending on the substitution pattern of the heteroring.

Synthesis of sex hormone-derived modified steroids possessing antiproliferative activity ⬇️

Synthesis, characterization and biological evaluation of some novel 17-isoxazoles in the estrone series.